Tuberculosis Control Priorities Defined by Using Cost-Effectiveness and Burden of Disease

查看全文 作　　者：[1]XuQ;[2]WuZL;等 机构地区：[1]DepartmentofEpidemiology,InstituteofBasicMedicalSciences,ChineseAcademyofMedicalSciences,ShoolofBasicMedicine,PekingUnionMedicalCollege,Beijing100005,China;[2]DepartmentofEpidemiology,InstituteofBasicMed 出　　处：《Biomedical and Environmental Sciences》索引2002年第15卷第2期,共5页 摘　　要：Objective To define TB control priorities using cost-effectiveness and burden of disease.Methods An assumed cohort of 2 000 cases was set up based on age-specific incidence of 794 newly registered smear-positive cases in Beijing in1994.Prognostic trees and model diagrams of infectivity with natural history and DOTS intervention were constructed based on the epidemiological parameters.Results DOTS reduced 89.19% of YLL,78.90% of YLD,and 99.98% of infectivity BOD.One DALY could be saved with 45.70% Yuan by DOTS with 3% discount.Sensitivity analysis showed that discount had effect on CER.Weight of age was insensitive to CER.The higher the DOTS coured rate,the more the cost-effectiveness.Conclusions DOTS is a good cost-effectiveness TB control strategy.Cost-effectiveness and burden of disease can be used to define TB control priorities. 关 键 词：结核 治疗费用 成本效益分析