Monitoring somatosensory evoked potentials in spinal cord ischemia-reperfusion injury

查看全文 作　　者：Yiming [1]Ji;Bin [1]Meng;Chenxi [1]Yuan;Huilin [1]Yang;Jun [1]Zou

机构地区：[1]Department of Orthopedic Surgery,the First Affiliated Hospital of Soochow University

出　　处：《Neural Regeneration Research》索引2013年第8卷第33期,共8页

基　　金：supported by the National Natural Science Foundation of China,No.81101370,81101399,81272018;the Natural Science Foundation of Jiangsu Province in China,No.BK2011303;Jiangsu Province Science and Technology Support Program(Social Development)in China,No.BE2011672;University Natural Science Research Foundation of Jiangsu Province for Higher Education,No.12KJB320008;College Graduate Research and Innovation Plan of Jiangsu Province in China,No.CXZZ11_0126 摘　　要：It remains unclear whether spinal cord ischemia-reperfusion injury caused by ischemia and other non-mechanical factors can be monitored by somatosensory evoked potentials.Therefore,we monitored spinal cord ischemia-reperfusion injury in rabbits using somatosensory evoked potential detection technology.The results showed that the somatosensory evoked potential latency was significantly prolonged and the amplitude significantly reduced until it disappeared during the period of spinal cord ischemia.After reperfusion for 30–180 minutes,the amplitude and latency began to gradually recover;at 360 minutes of reperfusion,the latency showed no significant difference compared with the pre-ischemic value,while the somatosensory evoked potential amplitude increased,and severe hindlimb motor dysfunctions were detected.Experimental findings suggest that changes in somatosensory evoked potential latency can reflect the degree of spinal cord ischemic injury,while the amplitude variations are indicators of the late spinal cord reperfusion injury,which provide evidence for the assessment of limb motor function and avoid iatrogenic spinal cord injury. 关键词：缺血再灌注损伤体感诱发电位脊髓损伤技术监测电位检测振幅和机械因素功能障碍

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Monitoring somatosensory evoked potentials in spinal cord ischemia-reperfusion injury

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