维普中文期刊产品整合服务

Regulatory Effects of Xylooligosaccharides on Intestinal Microbial Flora Proliferation and Defecation of BALB/c Mice

查看全文 作　　者：Tao [1]WEI;Hongtao [2]SHANG;Zhaolan [1]GAO;Li [1]WANG;Siyu [1]LI;Xue [1]HUANG;Mengrui [1]ZHENG 高影响力作者 机构地区：[1]College of Applied Arts and Science of Beijing Union University;[2]Medical Engineering Department of General Hospital under Beijing Area Command高影响力机构 出　　处：《Agricultural Biotechnology》索引2013年第2卷第3期,共3页高影响力期刊 基　　金：Supported by Funding Project for Academic Human Resources Development in Institutions of Higher Learning Under the Jurisdiction of Beijing Municipality(PHR201008293) 摘　　要：[Objective] This study aimed to investigate the regulatory effects of xylooligosaccharides on intestinal microbial flora proliferation and defecation of BALB/c mice.[Method] In the intestinal microbial flora proliferation regulation experiment, microflora quantities of Bifidobacterium, Lactobacillus, Enterobacter and Enterococci in excrements of BALB/c mice were determined after continuous administration of high-dose[1.0 g/(kg·bw)] and low-dose[0.5 g/(kg·bw)] xylooligosaccharides for 14 d.In the defecation regulation experiment, constipation model of BALB/c mice was established with compound diphenoxylate after continuous administration of high-dose and low-dose xylooligosaccharides for 21 d, to determine the first defecation time of black excrement, weight of black excrements within 6 h and rate of intestinal propulsion of constipation mice.[Result] Compared with the control group, after continuous administration of xylooligosaccharides for 14 d, microflora quantities of Lactobacillus and Bifidobacterium in excrements of BALB/c mice in low-dose and high-dose groups both increased significantly (P<0.05).After continuous administration of xylooligosaccharides, microflora quantities of Enterococci and Lactobacillus in control group were significantly raised (P<0.05 and P<0.01, respectively) compared with those before administration; microflora quantities of Enterococci in high-dose and low-dose groups were significantly reduced (P<0.05), while microflora quantities of Lactobacillus and Bifidobacterium and the B/E value increased significantly (P<0.05, P<0.01 and P<0.01, respectively).After continuous administration of xylooligosaccharides for 21 d, compared with the model group, the first defecation time of black excrement in high-dose and low-dose groups was significantly shortened (P<0.05), the total weight of black excrements within 6 h increased significantly (P<0.05) and the rate of intestinal propulsion was significantly enhanced (P<0.01).[Conclusion] Low-dose (0.5 g/Kg.bw) and high-dose (1 g/Kg.bw) xylooligosaccharides can improve the proliferation of intestinal microbial flora and prevent mice from constipation. 关 键 词：肠道微生物菌群 低聚木糖 调节作用 小鼠 排便 增殖 粪肠球菌 乳酸杆菌
相关文献

参考文献(7)

耦合文献(61)

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费