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Anethum graveolens Linn.(dill) extract enhances the mounting frequency and level of testicular tyrosine protein phosphorylation in rats

查看全文 作　　者：Sitthichai [1,2]IAMSAARD;Thawatchai [2]PRABSATTROO;Wannisa [1]SUKHORUM;Supaporn [2,3]MUCHIMAPURA;Panee [2]SRISAARD;Nongnut [1,2]UABUNDIT;Wipawee [2,3]THUKHAMMEE;Jintanaporn [2,3]WATTANATHORN 高影响力作者 机构地区：[1]Department of Anatomy,Faculty of Medicine,Khon Kaen University;[2]Integrative Complementary Alternative Medicine Research and Development Group,Faculty of Medicine,Khon Kaen University;[3]Department of Physiology,Faculty of Medicine,Khon Kaen University高影响力机构 出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》索引2013年第14卷第3期,共6页高影响力期刊 基　　金：Project (No.53-03-2-00-008) supported by the Office of Research Administration,Khon Kaen University,Thailand 摘　　要：Objective:To investigate the effect of Anethum graveolens(AG) extracts on the mounting frequency,histology of testis and epididymis,and sperm physiology.Methods:Male rats induced by cold immobilization before treating with vehicle or AG extracts [50,150,and 450 mg/kg body weight(BW)] via gastric tube for consecutive 1,7,and 14 d were examined for mounting frequency,testicular phosphorylation level by immunoblotting,sperm concentration,sperm acrosome reaction,and histological structures of testis and epididymis,respectively.Results:AG(50 mg/kg BW) significantly increased the mounting frequency on Days 1 and 7 compared to the control group.Additionally,rat testis treated with 50 mg/kg BW AG showed high levels of phosphorylated proteins as compared with the control group.In histological analyses,AG extract did not affect the sperm concentration,acrosome reaction,and histological structures of testis and epididymis.Conclusions:AG extract enhances the aphrodisiac activity and is not harmful to sperm and male reproductive organs. 关 键 词：外科学 临床 泌尿科学 男子性机性障碍
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