Hepatocellular carcinoma in cirrhotic patients with portal hypertension:Is liver resection always contraindicated?

查看全文 作　　者：Andrea [1]Ruzzenente;Alessandro [1]Valdegamberi;Tommaso [1]Campagnaro;Simone [1]Conci;Silvia [1]Pachera;Calogero [1]Iacono;Alfredo [1]Guglielmi

机构地区：[1]Department of Surgery,Division of General Surgery'A',GB Rossi Hospital,University of Verona

出　　处：《World Journal of Gastroenterology》索引2011年第17卷第46期,共6页

摘　　要：AIM:To analyze the outcome of hepatocellular car-cinoma(HCC)resection in cirrhosis patients,related to presence of portal hypertension(PH)and extent of hepatectomy.METHODS:A retrospective analysis of 135 patients with HCC on a background of cirrhosis was submitted to curative liver resection.RESULTS:PH was present in 44(32.5%)patients.Overall mortality and morbidity were 2.2% and 33.7%,respectively.Median survival time in patients with or without PH was 31.6 and 65.1 mo,respectively(P=0.047);in the subgroup with Child-Pugh class A cirrhosis,median survival was 65.1 mo and 60.5 mo,respectively(P=0.257).Survival for patients submitted to limited liver resection was not significantly different in presence or absence of PH.Conversely,median survival for patients after resection of 2 or more segments with or without PH was 64.4 mo and 163.9 mo,respectively(P=0.035).CONCLUSION:PH is not an absolute contraindication to liver resection in Child-Pugh class A cirrhotic patients,but resection of 2 or more segments should not be recommended in patients with PH. 关键词：肝硬化肝切除患者肝癌禁忌高压平均存活时间 PH值

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Hepatocellular carcinoma in cirrhotic patients with portal hypertension:Is liver resection always contraindicated?

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