Systematic review of health-related quality of life after esophagectomy for esophageal cancer

查看全文 作　　者：Marco [1]Scarpa;Stefano [1]Valente;Rita [1]Alfieri;Matteo [1]Cagol;Giorgio [1]Diamantis;Ermanno [2]Ancona;Carlo [1]Castoro

机构地区：[1]Oncological Surgery Unit,Veneto Institute of Oncology;[2]Department of Gastroint estinal and Surgical Sciences,University of Padova

出　　处：《World Journal of Gastroenterology》索引2011年第17卷第42期,共15页

摘　　要：This study is aimed to assess the long-term health-related quality of life(HRQL) of patients after esopha-gectomy for esophageal cancer in comparison with es-tablished norms,and to evaluate changes in HRQL during the different stages of follow-up after esopha-geal resection. A systematic review was performed bysearching medical databases(Medline,Embase andthe Cochrane Library) for potentially relevant studiesthat appeared between January 1975 and March 2011.Studies were included if they addressed the questionof HRQL after esophageal resection for esophage alcancer. Two researchers independently performed the study selection,data extraction and analysis processes.Twenty-one observational studies were included witha total of 1282(12-355) patients. Five studies were performed with short form-36(SF-36) and 16 with European Organization for Research and Treatment of Cancer(EORTC) QLQ C30(14 of them also utilized the disease-specific OES18 or its previous version OES24) .The analysis of long-term generic HRQL with SF-36showed pooled scores for physical,role and socialfunction after esophagectomy similar to United Statesnorms,but lower pooled scores for physical function,vitality and general health perception. The analysis of HRQL conducted using the Global EORTC C30 globalscale during a 6-mo follow-up showed that global scaleand physical function were better at the baseline. The symptom scales indicated worsened fatigue,dyspneaand diarrhea 6 mo after esophagectomy. In contrast,however,emotional function had significantly improved after 6 mo. In conclusion,short- and long-term HRQLis deeply affected after esophagectomy for cancer. The impairment of physical function may be a long-termconsequence of esophagectomy involving either the respiratory system or the alimentary tract. The short-and long-term improvement in the emotional function of patients who have undergone successful operationsmay be attributed to the impression that they have survived a near-death experience. 关键词：呼吸系统食管癌生活质量健康 MEDLINE 生理功能全球范围数据提取

相关文献

参考文献（69）
引证文献（16）
耦合文献（0）

参考文献(69)

引证文献(16)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Systematic review of health-related quality of life after esophagectomy for esophageal cancer

参考文献(69)

引证文献(16)

用户提示