Ethanol injection is highly effective for hepatocellular carcinoma smaller than 2cm

查看全文 作　　者：Maurizio [1]Pompili;Erica [1]Nicolardi;Valeria [1]Abbate;Luca [1]Miele;Laura [1]Riccardi;Marcello [2]Covino;Nicoletta De [1]Matthaeis;Antonio [1]Grieco;Raffaele [1]Landolfi;Gian Ludovico [1]Rapaccini

机构地区：[1]Department of Internal Medicine,Università Cattolica del Sacro Cuore;[2]Department of Emergency,Università Cattolica del Sacro Cuore

出　　处：《World Journal of Gastroenterology》索引2011年第17卷第26期,共7页

摘　　要：AIM:To analyze the long-term prognosis in a cohort of western cirrhotic patients with single hepatocellular carcinoma treated with ethanol injection.METHODS:One-hundred forty-eight patients with solitary hepatocellular carcinoma were enrolled.The tumor diameter was lower than 2 cm in 47 patients but larger in the remaining 101 patients.The impact of some pretreatment clinical and laboratory parameters and of tumor recurrence on patients' survival was assessed.RESULTS:Among the pre-treatment parameters,only a tumor diameter of less than 2 cm was an independent prognostic factor of survival.The occurrence of new nodules in other liver segments and the neoplastic portal invasion were linked to a poorer prognosis at univariate analysis.Patients with a single hepatocellular carcinoma smaller than 2 cm showed a better 5-year cumulativesurvival(73.0% vs 47.9%)(P = 0.009),3-year local recurrence rate(29.1% vs 51.5%)(P = 0.011),and 5-year distant intrahepatic recurrence rate(52.9% vs 62.8%)(P = 0.054) compared to patients with a larger tumor.CONCLUSION:The 5-year survival rate of patients with single hepatocellular carcinoma < 2 cm undergoing ethanol injection is excellent and comparable to that achieved using radiofrequency ablation. 关键词：注射治疗无水乙醇肝癌单因素分析射频消融生存率复发率患者

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Ethanol injection is highly effective for hepatocellular carcinoma smaller than 2cm

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