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Impact of obesity on the surgical outcome following repeat hepatic resection in Japanese patients with recurrent hepatocellular carcinoma

查看全文 作　　者：Tohru [1]Utsunomiya;Masahiro [1]Okamoto;Toshihumi [1]Kameyama;Ayumi [1]Matsuyama;Manabu [1]Yamamoto;Megumu [2]Fujiwara;Masaki [3]Mori;Shiomi [4]Aimitsu;Teruyoshi [1]Ishida 高影响力作者 机构地区：[1]Department of Surgery, Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital, Hiroshima, Japan;[2]Department of Pathology, Hiroshima RedCross Hospital and Atomic Bomb Survivors Hospital, Hiroshima730-8619, Japan;[3]Department of Radiology, Hiroshima Red CrossHospital and Atomic Bomb Survivors Hospital, Hiroshima730-8619, Japan;[4]Department of Internal Medicine of the Liver,Hiroshima Red Cross Hospital and Atomic Bomb SurvivorsHospital, Hiroshima 730-8619, Japan高影响力机构 出　　处：《World Journal of Gastroenterology》索引2008年第14卷第10期,共6页高影响力期刊 摘　　要：AIM: To evaluate the impact of obesity on the posto- perative outcome after hepatic resection in patients with hepatocellular carcinoma (HCC). METHODS: Data from 328 consecutive patients with primary HCC and 60 patients with recurrent HCC were studied. We compared the surgical outcomes between the non-obese group (body mass index: BMI < 25 kg/m2) and the obese group (BMI ≥ 25 kg/m2). RESULTS: Following curative hepatectomy in patients with primary HCC, the incidence of postoperative complications and the long-term prognosis in the non- obese group (n = 240) were comparable to those in the obese group (n = 88). Among patients with recurrent HCC, the incidence of postoperative complications after repeat hepatectomy was not significantly different between the non-obese group (n = 44) and the obese group (n = 16). However, patients in the obese group showed a significantly poorer long-term prognosis than those in the non-obese group (P < 0.05, five-yearsurvival rate; 51.9% and 92.0%, respectively). CONCLUSION: Obesity alone may not have an adverse effect on the surgical outcomes of patients with primary HCC. However, greater caution seems to be required when planning a repeat hepatectomy for obese patients with recurrent HCC. 关 键 词：肝细胞癌 肝切除术 体重指数 预后
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