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Effect of controlled low central venous pressure on renal function in major liver resection

查看全文 作  者:Yuyong Liu Mingxue Cai Shan'e Duan Xuemei Peng Yong Lai Yalan [1]Li 高影响力作者 机构地区:[1]Department of Anesthesia, The First Affiliated Hospital, Jinan University, Guangzhou 510630, China高影响力机构 出  处:《The Chinese-German Journal of Clinical Oncology》索引2008年第7卷第1期,共3页高影响力期刊 摘  要:Objective: To investigate the effects of low central venous pressure (LVCP) on blood loss and evaluate its influ- ence on renal function in patients undergoing hepatectomy. Methods: Forty-six patients, ASA classification I–III, undergoing liver resection were randomized into LCVP group (n = 23) and control group (n = 23). In LCVP group, CVP was maintained at 2–4 mmHg and MBP above 60 mmHg during hepatectomy, while in control group hepatectomy was performed routinely without lowering CVP. Volume of blood loss during hepatectomy, volume of blood transfusion, and changes of renal functions were compared between the two groups. Results: There were no significant differences in demographics, ASA score, type of hepatectomy, duration of inflow occlusion, operation time, weight of resected liver tissues, and renal functions between the two groups. LCVP group had a significantly lower volume of total intraoperative blood loss (P < 0.01) and RBC transfusion (P < 0.05). Conclusion: Lowering the CVP to less than 5 mmHg is a simple and effective technique to reduce blood loss and blood infusion during liver resection, and has no detrimental effects on renal functions. 关 键 词:控制性低中心静脉压 肝切除术 患者 肾功能
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