Effect of NCPB and VSPL on pain and quality of life in chronic pancreatitis patients

查看全文 作　　者：Andrzej [1]Basinski;Tomasz [2]Stefaniak;Ad [3]Vingerhoets;Wojciech [2]Makarewicz;Lukasz [2]Kaska;Aleksander [2]Stanek;Andrzej [2]J.Lachinski;Zbigniew [2]Sledzinski

机构地区：[1]Department of Emergency MedicineMedical University of Gdansk,Poland;[2]Department of GeneralEndocrine and Transplant Surgery,Medical University of Gdansk,Poland;[3]Department of Psychology and Healthand Research Institute for Psychology and Health,Tilburg University,the Netherlands

出　　处：《World Journal of Gastroenterology》索引2005年第11卷第32期,共5页

摘　　要：AIM: To compare the effects of neurolytic celiac plexus block (NCPB) and videothoracoscopic splanchnicectomy (VSPL) on pain and quality of life of chronic pancreatitis (CP) patients.METHODS: Forty-eight small duct CP patients were treated invasively with NCPB (n = 30) or VSPL (n = 18) in two non-randomized, prospective, case-controlled protocols due to chronic pain syndrome, and compared to a control group who were treated conservatively (n = 32). Visual analog scales were used to assess pain and opioid consumption rate was evaluated. In addition, the quality of life was measured using QLQ C-30 for NCPB and FACIT for VSPL.Although both questionnaires covered similar problems,they could not be compared directly one with another.Therefore, the studies were compared by meta-analysis methodology.RESULTS: Both procedures resulted in a significant positive effect on pain of CP patients. Opioids were withdrawn totally in 47.0% of NCPB and 36.4% of VSPL patients,and reduced in 53.0% and 45.4% of the respective patient groups. No reduction in opioid usage was observed in the control group. In addition, fatigue and emotional well-being showed improvements. Finally, NCPB demonstrated stronger positive effects on social support, which might possibly be attributed to earlier presentation of patients treated with NCPB.CONCLUSION: Both invasive pain treatment methods are effective in CP patients with chronic pain. 关键词：慢性胰腺炎 NCPB VSPL 内脏神经切除术生活质量疼痛

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Effect of NCPB and VSPL on pain and quality of life in chronic pancreatitis patients

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