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Uterine receptivity and the plasma membrane transformation

查看全文 作  者:Christopher R [1]MURPHY 高影响力作者 机构地区:[1]Department of Anatomy and Histology The University of Sydney, NSW 2006. Australia高影响力机构 出  处:《Cell Research》索引2004年第14卷第4期,共9页高影响力期刊 摘  要:This review begins with a brief commentary on the diversity of placentation mechanisms, and then goes on to examine the extensive alterations which occur in the plasma membrane of uterine epithelial cells during early pregnancy across species. Ultrastructural, biochemical and more general morphological data reveal that strikingly common phenomena occur in this plasma membrane during early pregnancy despite the diversity of placental types-from epitheliochorial to hemochorial, which ultimately form in different species. To encapsulate the concept that common morphological and molecular alterations occur across species, that they are found basolaterally as well as apically, and that moreover they are an ongoing process during much of early pregnancy, not just an event at the time attachment,brane during early pregnancy are key to uterine receptivity. 关 键 词:原生质膜转换 妊娠 子宫 胎盘形成
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