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| 1 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020，26，32： | 3 |
| 2 | 韩国社会工作教育中的文化能力问题显示文摘近年来,在多元文化主义背景的影响下,社会工作的文化能力培养已成为韩国社会工作发展的当务之急。检视了韩国不同文化族群的分布,提出培养文化共融能力的理论框架,并讨论了文化能力培养在韩国社会工作发展中的有效性,以及如何在韩国社会工作教育中真正落实文化能力培养,并对社会工作的文化能力教育中潜在的影响和要点进行了讨论。 | Jun Sung Hong Charu Stokes Soo-Jung Byoun Sharlene B C L Furuto Young Sook Kim 张宇 宋洁 | 2014 | 社会工作与管理2014，14，A04： | 3 |
| 3 | Foos Statistically lossless image compression for CR and DR显示文摘 | YOUNG S S WHITING B R | 1999 | SPIE1999，3658，： | 2 |
| 4 | Electrodeposition of p-i-n type CuInSe2 multilayers for photovoltaic applications显示文摘 | Chaure N B Young J Samantilleke A P | 2004 | Solar Energy Materials & Solar Cells2004，81，1： | 2 |
| 5 | Thin film transistor and diode addressed AMLCDs on polymer substrates显示文摘 | Young N D Bunn B M Wilks R W | 1997 | Journal of the Society for Information Display1997，5，3： | 2 |
| 6 | Sciberian Crootstock delays bloom of peach显示文摘 | YOUNG E OLCOTT-REID B | 1979 | Amer Soc Hort Sci1979，104，2： | 2 |
| 7 | The characteristics of a hydroxyapatite-chitosan-PMMA bone cement显示文摘 | SEOK B K YOUNG J K TAEK L Y | 2004 | Biomaterials2004，25，26： | 1 |
| 8 | Micro--injection Molding with the Infrared Assisted Mold Heating System显示文摘 | Yu M C Young W B Hsu P M | 2007 | Material Science and Engineering A2007，，： | 1 |
| 9 | Evaluating the Integration of Technology and Second Language Learning显示文摘 | Adair-Hauck B willingharn-McLain L Youngs B E | 2000 | CALICO Journal2000，，17： | 1 |
| 10 | Syntheses and properties of low-level melamine modified urea-melamine formaldehyde resin显示文摘 | Young No B Kim M G | 2004 | Journal of Applied Polymer Science2004，93，6： | 1 |
| 11 | Aberrant expression of cyclin A and cyclin B1 proteins in oral carcinoma显示文摘 | Kushner J Bradley G Young B | 1999 | JOral Pathol Med1999，28，2： | 1 |
| 12 | Evolution of colorectal cancer:change of pace and change of direction 显示文摘 | Jass J R Young J Leggett B A | 2002 | J Gastroenterol Hepatol2002，17，： | 1 |
| 13 | Ni-and Zn-promotion of γ-Al2O3 for the hydrolysis of COS under mild conditions显示文摘 | JOHN W WILIAMS B P YOUNG N | 2001 | Catalysis Communications2001，，2： | 1 |
| 14 | The course of geriatric depression with' reversible dementia':a controlled study显示文摘 | ALEXOPOULOS G MEYERS B S YOUNG R C | 1993 | Am J Psychiatry1993，150，11： | 1 |
| 15 | Compression tests of channelswith inclined simple edge stiffeners 显示文摘 | Young B Hancock G J | 2003 | Journal ofStructural Engineering ASCE2003，129，10： | 1 |
| 16 | Virally stimulated plasmacytoid dendritic cells pro-duce chemokines and induce migration of T and NKcells显示文摘 | MEGJUGORAC N YOUNG H A’AMRUTE S B etal | 2004 | J Leukoc Biol2004，75，50： | 1 |
| 17 | Syntheses and properties of low-level melamine-modified urea-melamine-formaldehyde resins 显示文摘 | YOUNG NO B KIM M G | 2004 | Journal of Applied Polymer Science2004，93，6： | 1 |
| 18 | Exogenous glucagon effects on health and reproductive performance of lactating dairy cows with mild fatty fiver显示文摘 | Bobe G Ametaj B N Young J W | 2007 | Anim Reprod Sci2007，102，3： | 1 |
| 19 | Evolutionary Dynamics of Staphylococcus Aureus During Progression from Carriage to Disease 显示文摘 | YOUNG B C T GOLUCHIK E M BATTY | 2012 | Proc Natl hcad Sci USA2012，109，12： | 1 |
| 20 | Inequities in Hospital Care, the Massachusetts Experience显示文摘 | Young G J Cohen B B | 1991 | Inquiry1991，，28： | 1 |
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