|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Harness the power of endogenous neural stem cells by biomaterials to treat spinal cord injury显示文摘Spinal cord injury(SCI)is a devastating medical condition without a cure.Reestablishment of neuronal connections after spinal cord injury is the'holy grail'of SCI research.However,grafting exogenous cells,including neural stem cells and a variety of adult somatic cells,has had very limited success[1].Two back-to-back papers published in | DE FILIPPIS Lidia SüDHOF Thomas C. PANG ZhiPing P. | 2015 | Science China(Life Sciences)2015，58，11： | 4 |
| 2 | Syntaxin-1蛋白的多重功能(英文)显示文摘Syntaxin-1是特异性地分布在神经细胞突触前质膜上的蛋白。它早期被作为分子量为35 kD的synaptotagmin-1结合蛋白,但很快就被认识到是细胞质膜融合的关键蛋白。Syntaxin-1通过与SNAP25和Synaptobrevin/VAMP蛋白聚合,进而形成被认为是神经突触囊泡融合必要因子的SNARE核心复合体。作为一个多结构域的蛋白,syntaxin-1与多个突触蛋白相互作用,其作用远超出了仅作为SNARE核心复合体中一个蛋白质成员的作用。本文着重介绍了有关syntaxin-1与其它SNARE组份蛋白、munc18蛋白和钙离子通道的相互作用及其功能的最新研究进展。全面揭示syntaxin-1作为SNARE核心复合体成员的功能以及超越这一功能的作用,还有待于对其结构以及与其它突触蛋白相互作用特性的进一步深刻理解。 | 孙坚原 Thomas C Südhof | 2011 | 生物物理学报2011，27，10： | 2 |
| 3 | Binding of F-spondin to amyloid-beta precursor protein:a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage显示文摘 | Ho A Südhof TC | 2004 | Proc Natl Acad Sci USA2004，101，8： | 1 |
| 4 | Essential Roles in Synaptic Plasticity for SynaptogyrinⅠand SynaptophysinⅠ显示文摘 | Janz R Südhof T C Hammer R E | 1999 | Neuron1999，24，3： | 1 |
| 5 | Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles 显示文摘 | Augustin I Rosenmund C Südhof TC | 1999 | Nature1999，400，： | 1 |
| 6 | RIBEYE, a component of synaptic ribbon: a protein's journey through evolution provides insight into synaptic ribbon function显示文摘 | Schmitz F Konigstorfer A S u dhof TC | 2000 | Neuron2000，28，： | 1 |
| 7 | gCap39, a calcium ion- and polyphosphoinositide-regulated actin capping protein 显示文摘 | YU F X JOHNSTON P A SI]DHOF T C | 1990 | Science1990，250，4986： | 1 |
| 8 | RIM1alpha and interactingproteins involved in presynaptic plasticity mediate prepulse inhibi-tion and additional behaviors linked to schizophrenia显示文摘 | Blundell J Kaeser PS Südhof TC | 2010 | J Neuros-ci2010，30，15： | 1 |
| 9 | Membrane fusion and exocytosis显示文摘 | Jahn R Südhof T C | | 0，，： | 1 |
| 10 | Synaptotagmin: a calcium sensor on the synaptic vesicle surface 显示文摘 | Petrenko AG Südhof TC | 1992 | Science1992，256，： | 1 |
| 11 | Rah3 and synaptotagmin:the yin and yang of synaptic membrane fusion 显示文摘 | Südhof TC | 1998 | Annu Rev Neurosci1998，21，： | 1 |
| 12 | Synptotagmins:why so many?显示文摘 | Südhof TC | 2002 | J Biol Chem2002，227，10： | 1 |
| 13 | The synaptic vesicle cycle revisited显示文摘 | Südhof TC | | 0，，02： | 1 |
| 14 | The synaptic vesicle cycle:a cascade of protein-protein interactions显示文摘 | Südhof TC | | 0，，6533： | 1 |
| 15 | Synaptic vesicle traffic:rush hour in the nerve terminal显示文摘 | Jahn R Südhof TC | | 0，，01： | 1 |
| 16 | Deconstructing complexin function in activating and clamping Ca2+-triggered exocytosis by comparing knockout and knockdown phenotypes 显示文摘 | Yang X Cao P SO dhof T C | 2013 | PNAS2013，110，20： | 1 |
| 17 | α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation显示文摘 | Burré J Sharma M Südhof TC | 2014 | Proc Natl Acad Sci USA2014，111，40： | 1 |
| 18 | C-terminal complexin sequence is selectively required for clamping and priming but not for Ca^2+ triggering of synaptic exocytosis 显示文摘 | Kaeser-Woo Y J Yang X Sv dhof T C | 2012 | J Neurosci2012，32，8： | 1 |
| 19 | α-Synuclein assembles into higherorder multimers upon membrane binding to promote SNARE complex formation显示文摘 | BurréJ Sharma M Südhof TC | 2014 | Proc Natl Acad Sci USA2014，111，： | 1 |
| 20 | Understanding Synapses: Past, Present, and Future显示文摘 | Thomas C. Südhof Robert C. Malenka | 2008 | Neuron2008，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员