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	题名	作者	年代	出处	被引量
1	Metastatic pattern in esophageal and gastric cancer:Influenced by site and histology显示文摘BACKGROUND Detailed information on metastatic patterns in of patients with esophageal and gastric cancer is limited.Early recognition of metastases is important to avoid futile locoregional treatments.Furthermore,knowledge on metastatic patterns is necessary for further development of personalized treatment modalities.AIM To gain insight into the metastatic pattern of gastroesophageal cancer.METHODS A nationwide retrospective autopsy study of 3876 patients with adenocarcinoma(AC)or squamous cell carcinoma(SCC)of the esophagus or stomach between 1990 and 2017 was performed.Only patient with metastases were included for analysis.The metastatic pattern was analyzed according to the primary tumor location and histological subtype.RESULTS Metastatic disease was found in 268 esophageal and 331 gastric cancer patients.In esophageal cancer,the most common metastatic locations were liver(56%),distant lymph nodes(53%)and lung(50%).Esophageal AC showed more frequently metastases to the peritoneum and bone compared with esophageal SCC.In gastric cancer,the most common metastatic locations were distant lymph nodes(56%),liver(53%)and peritoneum(51%).Intestinal-type AC of the stomach showed metastases to the liver more frequently,whereas metastases to the bone,female reproductive organs and colorectum were observed more frequently in diffuse-type gastric AC.CONCLUSION This study showed differences in metastatic patterns of patients with esophageal and gastric cancer according to the primary tumor location and histological subtype.	Moniek HP Verstegen Mitchell Harker Carlijn van de Water Jolanda van Dieren Niek Hugen Iris D Nagtegaal Camiel Rosman Rachel S van der Post	2020	World Journal of Gastroenterology2020，26，39：	9
2	Effect of regular physical activity on defecation pattern in middle-aged patients complaining of chronic constipation 显示文摘	De Schreyer AM Kelemans YC Peters HP	2005	Scand J Gastroenterology2005，40，4：	1
3	Pulmonary mucorrnycosis:radiologic findings in 32 cases显示文摘	McAdams HP Rosado de Christenson M Strollo DC	1997	AJR Am J Roentgenol1997，168，：	1
4	Patients with usual vulvar intraepithelial neoplasia-related vulvar cancer have an increased risk of cervical abnormalities显示文摘	de Bie RP van de Nieuwenhof HP Bekkers RL	2009	Br J Cancer2009，101，1：	1
5	Molec-ular methods for the identification of Aspergillus species显示文摘	Hinrikson HP Hurst SF de Aguirre L	2005	Med Mycol2005，43，1：	1
6	Benign hyperplastic nodules that originate in the peripheral zone of the prostate gland显示文摘	Oyen RH Van de voorde QM Van Poppel HP	1993	Radiology1993，189，：	1
7	Transrectal ultrasound imaging of the prostate:review and perspectives of recent developments显示文摘	Sedelaar JPM De la Rosette JJMCH Beerlage HP	1999	Prostate Cancer & Prostatic Diseases1999，2，5：	1
8	The role of inflammationin the development of chronic lung disease in neonates 显示文摘	De Dooy JJ Mahieu LM Van Bever HP	2001	Eur JPediatr2001，160，45：	1
9	Oral or IV prednisolone in the treatment of COPD exacerbations:a randomized,controlled,double-blind study显示文摘	de Jong YP Uil SM Grotjohan HP		0，，06：	1
10	Rituximab in minimal change nephropathy and focal segmental glomemlosclerosis:report of four cases and review of the literature显示文摘	Peters HP van de Kar NC Wetzels JF		0，，10：	1
11	Rituximab in minimal change nephropathy and focal segmental glomerulosclerosis : Report of four cases and review of the literature显示文摘	Peters HP van de Kar NC Wetzds JF	2008	Neth J Med2008，66，10：	1
12	Pathogenesis of rotavirusinduced bile duct obstruction (a model for human biliary atresia) in normal Balb/c and CB17 scid mice with severe combined immunodeficiency (SCID) 显示文摘	Qiao HP de Vincentes A Alashari M	1999	Pediatr Res1999，45，：	1
13	The arrangements of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus显示文摘	Staunton DE Dustin ML Erickson HP	1990	Cell1990，61，：	1
14	The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma显示文摘	Derksen PW de Gorter DJ Meijer HP	2003	Leukemia2003，17，4：	1
15	POU5F1 (OCT3/4)identifies cells with pluripotent potential in human germ cell tumors显示文摘	Looijenga LH Stoop H De Leeuw HP	2003	Cancer Res2003，63，9：	1
16	From the archives of the AFIP: localized fibrous tum~3r of the pleura 显示文摘	Rosado- de - Christenson ML Abbott GF McAdams HP	2003	Radographics2003，23，3：	1
17	Potential benefits and hazards of physical activity and exer- cise on the gastrointestinal tract 显示文摘	Peters HP De Vries WR Vanberge- Henegouwen GP	2001	Gut2001，48，3：	1
18	Using a reduced spot size for intensity modulated proton therapy potentially improves sali- vary gland-sparing in oropharyngeal cancer显示文摘	van de Water TA Lomax AJ Bijl HP	2012	Int J Radiat Oncol Biol Phys2012，82，：	1
19	Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs显示文摘	de Vos AF van Meurs M Brok HP	2002	J Immunol2002，169，10：	1
20	Assessment of human exposure to fumonisin Bl显示文摘	de Nijs M van Egmond HP Nauta M	1998	J Food Prot1998，61，：	1

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