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| 1 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 2 | The value of pulse cyclophosphamide in ANCA-associated vasculitis:meta-analysis and critical review显示文摘 | de Groot K Adu D Savage CO | 2001 | Nephrol Dial Transplant2001，16，10： | 1 |
| 3 | Nucleation and growth of mullite whiskers from lanthanum-doped aluminosilicate melts显示文摘 | Regiani I Magalh(a)es W L E De Souza D P F Paiva-Santos CO De Souza M F | | 0，，01： | 1 |
| 4 | In situ analyses ofgenome instability in breast cancer显示文摘 | Chin K de Solorzano CO Knowles D | 2004 | Nat Genet2004，36，9： | 1 |
| 5 | Binding of perfluVorinated fatty acids to serum proteins 显示文摘 | Jones P D Hu W De Co^n W | 2003 | Environmental Toxicology and Chemistry2003，22，1： | 1 |
| 6 | The value of pulse cyclophosphamide in ANCA-associated vasculitis: meta-analysis and critical review 显示文摘 | de Groot K Adu D Savage CO | 2001 | Nephrol Dial Transplant2001，16，10： | 1 |
| 7 | 绿色葱葱显示文摘四月,在渐吹渐暖的春风里,春天以它惯有的姿态与步伐曼妙开来:樱花粉了、迎春黄了,桃花红了……在春天的信笺里,也写满了盎然的绿意。喜欢繁花如抱的春野,更喜欢东风吹拂枝上的新绿。因为,那生生不息的绿意是生命蜕变的力量。绿色常在,便有风轻云淡的境界,安宁静谧的祥和。生活在钢筋水泥的都市,空气中雾霾弥漫,寸土寸金绿地难觅,快节奏的生活让我们远离自然。见惯了城市的喧嚣与奢华,你是否在寻找那片郁郁葱葱的绿色? | Dco Chez Moi Bordallo and Van Verre Charles Viancin Costa Nova Cozy Living Eline Rousseau Isabel Vissouze Joseph Joseph Johan Weernink Linum Loop Design Maison de Vacances Nick Fraser Piyush Suri Rosemarie Schulz Tissage Art de Lys Wildlife Garden AB 伏平 范嘉苑 | 2016 | 现代装饰(家居)2016，0，4： | 0 |
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