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| 1 | Mathematic principles of interrupted-sampling repeater jamming (ISRJ)显示文摘Coherent jamming is one of the important trends in modern radar electronic war- fare. High-speed sampling of wideband radio frequency (RF) signals and high iso- lation of two receive-transmit antennas are key technologies for the realization of coherent jamming. However, these technologies present significant challenges to engineering application. In this paper, a novel repeater jamming based on inter- rupted sampling technique is presented. For a jammer with a receive-transmit time-sharing antenna, a radar signal is sampled with a low rate by the jammer. Then, a train of false targets will be achieved after the jamming signal feed the matched filter of a pulse compression radar. For the case of the linear frequency modulated (LFM) pulse compression radars, mathematic principles of the interrupted-sam- pling repeater jamming is developed, and then the efficiency of the jamming is de- scribed and stated as expressions of key parameters which are also beneficial to the jamming design for other coherent radars. | WANG XueSong LIU JianCheng ZHANG WenMing FU QiXiang LIU Zhong XIE XiaoXia | 2007 | Science in China(Series F)2007，50，1： | 53 |
| 2 | New vacuum solar telescope and observations with high resolution显示文摘The New Vacuum Solar Telescope(NVST) is a one meter vacuum solar telescope that aims to observe fine structures on the Sun. The main goals of NVST are high resolution imaging and spectral observations, including measurements of the solar magnetic field. NVST is the primary ground-based facility used by the Chinese solar research community in this solar cycle. It is located by Fuxian Lake in southwest China, where the seeing is good enough to perform high resolution observations. We first introduce the general conditions at the Fuxian Solar Observatory and the primary science cases of NVST. Then, the basic structures of this telescope and instruments are described in detail. Finally, some typical high resolution data of the solar photosphere and chromosphere are also shown. | Zhong Liu Jun Xu Bo-Zhong Gu Sen Wang Jian-Qi You Long-Xiang Shen Ru-Wei Lu Zhen-Yu Jin Lin-Fei Chen Ke Lou Zhi Li Guang-Qian Liu Zhi Xu Chang-Hui Rao Qi-Qian Hu Ru-Feng Li Hao-Wen Fu Feng Wang Men-Xian Bao Ming-Chan Wu Bo-Rong Zhang | 2014 | Research in Astronomy and Astrophysics2014，14，6： | 37 |
| 3 | Prevention of postoperative intracranial infection in patients with cerebrospinal fluid rhinorrhea显示文摘背景 Intracranial 感染是学习试图与脑髓的液体 rhinorrhea 在病人识别手术后的 intracranial 感染的风险因素并且为 167 个病人全部的 prevention.Methods A 建议建议的 neurosurgery.This 的普通手术后的复杂并发症( 113 男性和 54 男性, 34.4 年的平均年龄)与四年级生操作的脑髓的液体 rhinorrhea ,作者是回顾地,收集的 reviewed.The 数据包括了病原学,以前的历史。 | YANG Zhi-jun ZHONG Hong-liang WANG Zhen-min ZHAO Fu LIU Pi-nan | 2011 | Chinese Medical Journal2011，，24： | 34 |
| 4 | The Role of Fibrocyte in the Pathogenesis of Silicosis显示文摘Exposure to free silica induces silicosis and myofibroblasts are regarded as primary effector cells.Fibrocytes can differentiate into myofibroblast.Therefore,the present study was designed to investigate whether | LI Juan YAO Wu HOU Jian Yong ZHANG Lin BAO Lei CHEN Hui Ting WANG Di YUE Zhong Zheng LI Yi Ping ZHANG Miao YU Xing Hao ZHANG Jian Hui QU Ya Qian HAO Chang Fu | 2018 | Biomedical and Environmental Sciences2018，31，4： | 20 |
| 5 | Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients显示文摘 | ZHENG Ying CAI Guang-yan CHEN Xiang-mei FU Ping CHEN Jiang-hua DING Xiao-qiang YU Xue-qing LIN Hong-li LIU Jian XIE Ru-juan WANG Li-ning NI Zhao-hui LIU Fu-you YIN Ai-ping XING Chang-ying WANG Li SHI Wei LIU Jian-she HE Ya-ni DING Guo-hua LI Wen-ge WU Guang-li MIAO Li-ning CHEN Nan SU Zhen MEI Chang-lin ZHAO Jiu-yang GU Yong BAI Yun-kai LUO Hui-min LIN Shan CHEN Meng-hua GONG Li YANG Yi-bin YANG Xiao-ping LI Ying WAN Jian-xin WANG Nian-song LI Hai-ying XI Chun-sheng HAO Li XU Yan FANG Jing-ai LIU Bi-cheng LI Rong-shan WANG Rong ZHANG Jing-hong WANG Jian-qin LOU Tan-qi SHAO Feng-min MEI Feng LIU Zhi-hong YUAN Wei-jie SUN Shi-ren ZHANG Ling ZHOU Chun-hua CHEN Qin-kai JIA Shun-lian GONG Zhi-feng GUAN Guang-ju XIA Tian ZHONG Liang-bao | 2013 | Chinese Medical Journal2013，，12： | 16 |
| 6 | Rapid growth cost in “all-fish” growth hormone gene transgenic carp:Reduced critical swimming speed显示文摘Evidence has accumulated that there is a trade-off between benefits and costs associated with rapid growth. A trade-off between growth rates and critical swimming speed (Ucrit) had been also reported to be common in teleost fish. We hypothesize that growth acceleration in the F3 generation of 'all-fish' growth hormone gene (GH) transgenic common carp (Cyprinus carpio L.) would reduce the swimming abilities. Growth and swimming performance between transgenic fish and non-transgenic controls were compared. The results showed that transgenic fish had a mean body weight 1.4―1.9-fold heavier,and a mean specific growth rate (SGR) value 6%―10% higher than the controls. Transgenic fish,however,had a mean absolute Ucrit (cm/s) value 22% or mean relative Ucrit (BL/s) value 24% lower than the controls. It suggested that fast-growing 'all-fish' GH-transgenic carp were inferior swimmers. It is also supported that there was a trade-off between growth rates and swimming performance,i.e. faster-growing individuals had lower critical swimming speed. | LI DeLiang FU CuiZhang HU Wei ZHONG Shan WANG YaPing ZHU ZuoYan | 2007 | Chinese Science Bulletin2007，52，11： | 14 |
| 7 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 8 | The first observation and data reduction of the Multi-wavelength Spectrometer on the New Vacuum Solar Telescope显示文摘The Multi-wavelength Spectrometer is a medium-dispersion(R^130 000)grating spectrometer installed on the New Vacuum Solar Telescope at the Fuxian Solar Observatory,Yunnan Astronomical Observatory,Chinese Academy of Sciences.It is designed to accurately observe the velocity and magnetic fields of the Sun.The present configuration of this spectrometer allows us to simultaneously observe three different solar spectral lines.This work is dedicated to showing the first observations carried out in both the Hαand Ca II 8542 A lines.We give a detailed description of the data reduction process,focusing on the retrieval of a flat field from the high-resolution spectral data.Two different methods are also performed and compared to eliminate the residual fringe in the reduced data.The real spectral resolution and instrumental profile are analyzed based on the final results,which indicate that this spectrometer presently satisfies the expected performance and it is ready for further scientific observations. | Rui Wang Zhi Xu Zhen-Yu Jin Zhi Li Yu Fu Zhong Liu | 2013 | Research in Astronomy and Astrophysics2013，13，10： | 13 |
| 9 | Long-term Efficacy of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: A 5-year Follow-up Study in China显示文摘 | Lu-Lu Jiang Jin-Long Liu Xiao-Li Fu Wen-Biao Xian Jing Gu Yan-Mei Liu Jing Ye Jie Chen Hao Qian Shao-Hua Xu Zhong Pei Ling Chen | 2015 | Chinese Medical Journal2015，，18： | 13 |
| 10 | Optimal design of anchor cables for slope reinforcement based on stress and displacement fields显示文摘How to determine reasonable position and length of anchor cable is a frequently encountered but not well addressed problem in slope reinforcement projects. In this paper, the variable-modulus elastoplastic strength reduction method(SRM) is used to obtain the stress field, displacement field, and factor of safety of slope. Slope reinforcement using anchor cables is modeled by surface loading, i.e. different distributions of surface loading represent various reinforcement schemes. Optimal reinforcement scheme of anchor cables can be determined based on slope stress and displacement fields. By comparing the factor of safety and stress field before and after slope reinforcement, it is found that better reinforcement results can be achieved if strong reinforcement is applied upon the regions with high stress and large displacement. This method can well optimize the arrangement of anchor cables. In addition,several cases are employed to verify the proposed method. | Guanghua Yang Zhihui Zhong Yucheng Zhang Xudong Fu | 2015 | Journal of Rock Mechanics and Geotechnical Engineering2015，7，4： | 12 |
| 11 | Effect of high glucose levels on the calcification of vascular smooth muscle cells by inducing osteoblastic differentiation and intracellular calcium deposition via BMP-2/Cbfα-1 pathway显示文摘In this paper,we investigate the effect and the possible mechanism of high glucose levels on the calcification of human aortic smooth muscle cells (HASMCs).HASMCs were divided into four groups: normal glucose group (NG),osmolality control group (OC),high glucose group (HG,HASMCs culture medium containing 30 mmol/L glucose),and high glucose plus recombinant human Noggin protein (bone morphogenetic protein-2 (BMP-2) antagonist) group (HN).The mRNA levels and the protein expressions of BMP-2 and core binding factor alpha-1 (Cbfα-1) were measured by real-time quantitative polymerase chain reaction (PCR) and Western blot.After induced by 10 mmol/L β-glycerol phosphoric acid,cells were harvested for assessments of alkaline phosphatase (ALP) activities at Days 1,2,and 3,and intracellular calcium contents at Days 7 and 14,respectively.High glucose levels increased the mRNA levels and the protein expressions of BMP-2 and Cbfα-1 (P<0.05).The expression of Cbfα-1 was partially blocked by Noggin protein (P<0.05),while BMP-2 was not (P>0.05).After being induced by β-glycerol phosphoric acid,high glucose levels increased the ALP activity [(48.63±1.03) vs.(41.42±2.28) U/mg protein,Day 3;P<0.05] and the intracellular calcium content [(2.76±0.09) vs.(1.75±0.07) μmol/mg protein,Day 14;P<0.05] in a time-dependent manner when compared with the NG group,while the ALP activity could not be blocked by Noggin protein [(48.63±1.03) vs.(47.37±0.97) U/mg protein,Day 3;P>0.05].These results show that high glucose levels can evoke the calcification of HASMCs by inducing osteoblastic trans-differentiation and intracellular calcium deposition via the BMP-2/Cbfα-1 pathway,which can be partially blocked by Noggin protein. | Fang LIU Hui ZHONG Jing-yuan LIANG Ping FU Zhi-juan LUO Li ZHOU Rong GOU Jun HUANG | 2010 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2010，11，12： | 12 |
| 12 | Improving grain yield, nitrogen use efficiency and radiation use efficiency by dense planting, with delayed and reduced nitrogen application, in double cropping rice in South China显示文摘Improving both grain yield and resource use efficiencies simultaneously is a major challenge in rice production.However,few studies have focused on integrating dense planting with delayed and reduced nitrogen application to enhance grain yield,nitrogen use efficiency (NUE) and radiation use efficiency (RUE) in rice (Oryza sativa L.) in the double rice cropping system in South China.A high-yielding indica hybrid rice cultivar (Yliangyou 143) was grown in field experiments in Guangxi,South China,with three cultivation managements:farmers’practice (FP),dense planting with equal N input and delayed N application (DPEN) and dense planting with reduced N input and delayed N application (DPRN).The grain yields of DPRN reached 10.6 and 9.78 t ha^(–1) in the early and late cropping seasons,respectively,which were significantly higher than the corresponding yields of FP by 23.9–29.9%.The grain yields in DPEN and DPRN were comparable.NUE in DPRN reached 65.2–72.9 kg kg^(–1),which was 61.2–74.1% higher than that in FP and 24.6–30.2% higher than that in DPEN.RUE in DPRN achieved 1.60–1.80 g MJ^(–1),which was 28.6–37.9% higher than that in FP.The productive tiller percentage in DPRN was 7.9–36.2% higher than that in DPEN.Increases in crop growth rate,leaf area duration,N uptake from panicle initiation to heading and enhancement of the apparent transformation ratio of dry weight from stems and leaf sheaths to panicles all contributed to higher grain yield and higher resource use efficiencies in DPRN.Correlation analysis revealed that the agronomic and physiological traits mentioned above were significantly and positively correlated with grain yield.Comparison trials carried out in Guangdong in 2018 and 2019 also showed that DPRN performed better than DPEN.We conclude that DPRN is a feasible approach for simultaneously increasing grain yield,NUE and RUE in the double rice cropping system in South China. | FU You-qiang ZHONG Xu-hua ZENG Jia-huan LIANG Kai-ming PAN Jun-feng XIN Ying-feng LIU Yan-zhuo HU Xiang-yu PENG Bi-lin CHEN Rong-bing HU Rui HUANG Nong-rong | 2021 | Journal of Integrative Agriculture2021，20，2： | 12 |
| 13 | Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota显示文摘Morinda officinalis oligosaccharides(MOO) are an oral drug approved in China for the treatment of depression in China. However, MOO is hardly absorbed so that their anti-depressant mechanism has not been elucidated. Here, we show that oral MOO acted on tryptophan → 5-hydroxytryptophan(5-HTP) → serotonin(5-HT) metabolic pathway in the gut microbiota. MOO could increase tryptophan hydroxylase levels in the gut microbiota which accelerated 5-HTP production from tryptophan;meanwhile, MOO inhibited 5-hydroxytryptophan decarboxylase activity, thus reduced 5-HT generation,and accumulated 5-HTP. The raised 5-HTP from the gut microbiota was absorbed to the blood, and then passed across the blood-brain barrier to improve 5-HT levels in the brain. Additionally, pentasaccharide,as one of the main components in MOO, exerted the significant anti-depressant effect through a mechanism identical to that of MOO. This study reveals for the first time that MOO can alleviate depression via increasing 5-HTP in the gut microbiota. | Zheng-Wei Zhang Chun-Sheng Gao Heng Zhang Jian Yang Ya-Ping Wang Li-Bin Pan Hang Yu Chi-Yu He Hai-Bin Luo Zhen-Xiong Zhao Xin-Bo Zhou Yu-Li Wang Jie Fu Pei Han Yu-Hui Dong Gang Wang Song Li Yan Wang Jian-Dong Jiang Wu Zhong | 2022 | Acta Pharmaceutica Sinica B2022，12，8： | 12 |
| 14 | An experimental and thermodynamic equilibrium investigation of the Pb,Zn,Cr,Cu,Mn and Ni partitioning during sewage sludge incineration显示文摘The effects of different chlorides and operational conditions on the distribution and speciation of six heavy metals(Pb, Zn, Cr, Cu, Mn and Ni) during sludge incineration were investigated using a simulated laboratory tubular-furnace reactor. A thermodynamic equilibrium investigation using the Fact Sage software was performed to compare the experimental results. The results indicate that the volatility of the target metals was enhanced as the chlorine concentration increased. Inorganic-Cl influenced the volatilization of heavy metals in the order of Pb > Zn > Cr > Cu > Mn > Ni. However, the effects of organic-Cl on the volatility of Mn, Pb and Cu were greater than the effects on Zn, Cr and Ni.With increasing combustion temperature, the presence of organic-Cl(PVC) and inorganic-Cl(NaCl) improved the transfer of Pb and Zn from bottom ash to fly ash or fuse gas. However,the presence of chloride had no obvious influence on Mn, Cu and Ni. Increased retention time could increase the volatilization rate of heavy metals; however, this effect was insignificant. During the incineration process, Pb readily formed Pb SiO4 and remained in the bottom ash. Different Pb compounds, primarily the volatile PbCl2, were found in the gas phase after the addition of NaCl; the dominant Pb compounds in the gas phase after the addition of PVC were PbCl2, Pb(ClO4)2and Pb Cl2O4. | Jingyong Liu Jiewen Fu Xun'an Ning Shuiyu Sun Yujie Wang Wuming Xie Shaosong Huang Sheng Zhong | 2015 | Journal of Environmental Sciences2015，27，9： | 11 |
| 15 | Artificial intelligence in drug design显示文摘Thanks to the fast improvement of the computing power and the rapid development of the computational chemistry and biology,the computer-aided drug design techniques have been successfully applied in almost every stage of the drug discovery and development pipeline to speed up the process of research and reduce the cost and risk related to preclinical and clinical trials.Owing to the development of machine learning theory and the accumulation of pharmacological data, the artificial intelligence(AI) technology, as a powerful data mining tool, has cut a figure in various fields of the drug design, such as virtual screening,activity scoring, quantitative structure-activity relationship(QSAR) analysis, de novo drug design, and in silico evaluation of absorption, distribution, metabolism, excretion and toxicity(ADME/T) properties. Although it is still challenging to provide a physical explanation of the AI-based models, it indeed has been acting as a great power to help manipulating the drug discovery through the versatile frameworks. Recently, due to the strong generalization ability and powerful feature extraction capability,deep learning methods have been employed in predicting the molecular properties as well as generating the desired molecules,which will further promote the application of AI technologies in the field of drug design. | Feisheng Zhong Jing Xing Xutong Li Xiaohong Liu Zunyun Fu Zhaoping Xiong Dong Lu Xiaolong Wu Jihui Zhao Xiaoqin Tan Fei Li Xiaomin Luo Zhaojun Li Kaixian Chen Mingyue Zheng Hualiang Jiang | 2018 | Science China(Life Sciences)2018，61，10： | 10 |
| 16 | Decolorization on Indigo Dyeing Wastewater by Laccase from Coriolus versicolor显示文摘[Object]The study aimed to discuss the decolorization on indigo dyeing wastewater by laccase from Coriolus versicolor.[Method]Firstly,the effects of temperature,pH,indigo concentration,HBT concentration,laccase dosage on the decolorization of indigo dyeing wastewater by laccase /HBT,and then the synergism of laccase and acid cellulase was analyzed.[Result]Using ABTS as the substrate,the kinetic parameters,K m and V max,were 0.318 mmol/L and 0.035 5 mmol/(L·min) respectively.The decolorization rate of indigo reached 96.5% when the laccase acted on indigo for 40 min with HBT as an introducer at temperature 50 ℃,pH =4.5,indigo concentration 100 mg /L,HBT concentration 0.1% and laccase dosage 100 IU /L.Due to the synergism of laccase and acid cellulase during the bio-finishing of blue jeans,the backstaining degree of blue jeans reduced by 85% when the amount of laccase added was 15 000 IU /kg.Menawhile,the synergism of the laccase and acid cellulase decreased indigo concentration in wastewater by 83.8%.[Conclusion] The laccase from Coriolus versicolor had a good prospect in the bio-finishing of blue jeans and the decolorization of indigo dyeing wastewater. | Enli Gao Weijia Zhong Xiaolan Fu Fushan Chen Zhigang Ye | 2013 | Meteorological and Environmental Research2013，4，1： | 10 |
| 17 | Epidemiological Analysis on Reported Hepatitis C Cases in China from 2012 to 2016显示文摘Viralhepatitisisanimportantchallengeto publichealthworldwide.AshepatitisBiswell controlledduetovaccination,thediseaseburden causedbythespreadofhepatitisChasbecome increasinglyprominent.HepatitisCisaninfectious diseasethatismainlyblood-borne.Therateof chronicity ranges from 55%to 85%after people are infected with the hepatitis C virus (HCV)[1-2]. Twenty yearsafterinfectioninthegeneralpopulation,the incidence of cirrhosis ranges from 5%to 15%[3]. | HEI Fa Xin YE Shao Dong DING Guo Wei PANG Lin WANG Xiao Chun LIU Zhong Fu | 2018 | Biomedical and Environmental Sciences2018，31，10： | 10 |
| 18 | Land-surface processes and summer-cloud-precipitation characteristics in the Tibetan Plateau and their effects on downstream weather:a review and perspective显示文摘Correct understanding of the land-surface processes and cloud-precipitation processes in the Tibetan Plateau(TP)is an important prerequisite for the study and forecast of the downstream activities of weather systems and one of the key points for understanding the global atmospheric movement.In order to show the achievements that have been made,this paper reviews the progress on the observations for the atmospheric boundary layer,land-surface heat fluxes,cloud-precipitation distributions and vertical structures by using ground-and space-based multiplatform,multisensor instruments and the effect of the cloud system in the TP on the downstream weather.The results show that the form drag related to the topography,land-atmosphere momentum and scalar fluxes is an important part of the parameterization process.The sensible heat flux decreased especially in the central and northern TP caused by the decrease in wind speeds and the differences in the ground-air temperatures.Observations show that the cloud and precipitation over the TP have a strong diurnal variation.Studies also show the compressed-air column in the troposphere by the higher-altitude terrain of the TP makes particles inside clouds vary at a shorter distance in the vertical direction than those in the non-plateau area so that precipitation intensity over the TP is usually small with short duration,and the vertical structure of the convective precipitation over the TP is obviously different from that in other regions.In addition,the influence of the TP on severe weather downstream is preliminarily understood from the mechanism.It is necessary to use model simulations and observation techniques to reveal the difference between cloud precipitation in the TP and non-plateau areas in order to understand the cloud microphysical parameters over the TP and the processes of the land boundary layer affecting cloud,precipitation and weather in the downstream regions. | Yunfei Fu Yaoming Ma Lei Zhong Yuanjian Yang Xueliang Guo Chenghai Wang Xiaofeng Xu Kun Yang Xiangde Xu Liping Liu Guangzhou Fan Yueqing Li Donghai Wang | 2020 | National Science Review2020，7，3： | 10 |
| 19 | Carcinogenic potential of duodenal reflux juice from patients with long-standing postgastrectomy显示文摘AIM To determine, whether study on thecarcinogenic potential of reflux juice frompatients with remote gastrectomy could clarifythe inherent relationship between duodenalreflux and gastric stump cancer.METHODS A total of 37 reflux juice samples(13 Billroth T, 24 Billroth Ⅱ ) were employed inthe present study. A two- stage transformationassay using BALB/c 3T3 cells was carried out totest the initiating or promoting activity of thesesamples.RESULTS Two of 18 (11.1%) reflux samplesexerted initiating activities, whereas 9/19(47.4%) samples enhanced the MNNG-initiafingcell transformation, suggesting the duodenalreflux juice might more frequently possess thetumor-promoter activity (P = 0. 029). In addition,there was no difference in initiating activities ofthe samples irrespective of surgical procedures(P=0.488), while Billroth Ⅱ samples exhibitedstronger tumor-promoter activity than Billroth Ⅰsamples (P = 0.027). Furthermore, the promoteractivities were well correlated with thehistological changes of the stomas (rs = 0.625,P = 0.004), but neither their cytotoxicities norinitiating activities had this correlation( Probabilities were 0.523 and 0.085,respectively).CONCLUSION The duodenal reflux juice frompatients with remote postgastrectomy did havecarcinogenic potential, and suggested thattumor-promoting activity should principallyaccount for the high incidence of gastric cancerin gastrectomy patients. In contrast, it isdifficult to explain the high stump-cancerincidence with the 'N-nitroso compounds'theory-a popular theory for the intact stomachcarcinogenesis, and it seemed to be justified tofocus chemoprevention of this cancer on thetumor-promoting potential of reflux juice. | Zhe Fu Ma~1 Zhong Yu Wang~1 Jun Ran Zhang~2 Peng Gong~1 Hai Long Chen~1 ~1Departrnent of General Surgery,First Hospital,Dalian Medical University,Dalian 116011,China ~2Department of Radiation Oncology,Massachusetts General Hospital and Harvard Medical School,Charlestown,MA 02129,USADr.Zhe Fu Ma graduated from Shanxi Medical College in 1993,nowPh.D.,M.D.in Department of Surgery,Dalian Medical University,majoring gastroenteric cancer,having 4 papers published.Correspondence to:Dr.Zhe Fu Ma.Department of General Surgery,First Hospital,Dalian Medical University,Dalian 116011,China Tel.0086-411-4720334 | 2001 | World Journal of Gastroenterology2001，7，3： | 9 |
| 20 | Optically pumped terahertz sources显示文摘High-power terahertz(THz) generation in the frequency range of 0.1-10 THz has been a fast-developing research area ever since the beginning of the THz boom two decades ago, enabling new technological breakthroughs in spectroscopy, communication, imaging,etc. By using optical(laser) pumping methods with near-or mid-infrared(IR) lasers, flexible and practical THz sources covering the whole THz range can be realized to overcome the shortage of electronic THz sources and now they are playing important roles in THz science and technology. This paper overviews various optically pumped THz sources, including femtosecond laser based ultrafast broadband THz generation, monochromatic widely tunable THz generation, single-mode on-chip THz source from photomixing, and the traditional powerful THz gas lasers. Full descriptions from basic principles to the latest progress are presented and their advantages and disadvantages are discussed as well. It is expected that this review gives a comprehensive reference to researchers in this area and additionally helps newcomers to quickly gain understanding of optically pumped THz sources. | ZHONG Kai SHI Wei XU DeGang LIU PengXiang WANG YuYe MEI JiaLin YAN Chao FU ShiJie YAO JianQuan | 2017 | Science China(Technological Sciences)2017，60，12： | 9 |
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