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| 1 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 2 | Ecological and environmental explanation of microbiotic crusts on sand dune scales in the Gurbantonggut Desert, Xinjiang显示文摘Results obtained from the field investigation and the analysis in laboratory show that many species of microbiotic crusts of lichens, mosses and algae develop extensively in the Gurbantonggut Desert, Xinjiang. The formation, species and distribution are closely related to the environmental conditions at the different positions of sand dunes. The animalcule crusts develop mainly on the mobile or semi-mobile sand surface of dune tops, the alga crusts develop mainly at the upper to middle parts of dune slopes, the lichen crusts develop at middle and lower parts of dune slopes, and the moss crusts are mainly distributed at the lower part of dune slopes and the interdune lowlands. The species, thickness and developing degree of microbiotic crusts increase from the upper part to the middle and lower parts of dune slopes and the interdune lowlands, and an obvious contrast between the microbiotic crusts and the different species of plant communities forms. The development and differentiation of microbiotic crusts at the different positions of dunes are the ecological appearance and the natural selection of synthetic adaptability of the different microbiotic crust species to the local environmental conditions, and are closely related to the ecological conditions, such as the physiochemical properties of soils and stability of topsoil texture. | CHEN Yaning LI Weihong ZHOU Zhibing LIU Jiazhen | 2005 | Progress in Natural Science:Materials International2005，15，12： | 5 |
| 3 | Using zebrafish as the model organism to understand organ regeneration显示文摘The limited regenerative capacity of several organs, such as central nervous system(CNS), heart and limb in mammals makes related major diseases quite difficult to recover. Therefore, dissection of the cellular and molecular mechanisms underlying organ regeneration is of great scientific and clinical interests. Tremendous progression has already been made after extensive investigations using several model organisms for decades. Unfortunately, distance to the final achievement of the goal still remains. Recently, zebrafish became a popular model organism for the deep understanding of regeneration based on its powerful regenerative capacity, in particular the organs that are limitedly regenerated in mammals. Additionally, zebrafish are endowed with other advantages good for the study of organ regeneration. This review summarizes the recent progress in the study of zebrafish organ regeneration, in particular regeneration of fin, heart, CNS, and liver as the representatives. We also discuss reasons of the reduced regenerative capacity in higher vertebrate, the roles of inflammation during regeneration, and the difference between organogenesis and regeneration. | SHI WenChao FANG ZhiBing LI Li LUO LingFei | 2015 | Science China(Life Sciences)2015，58，4： | 5 |
| 4 | A Teosinte-derived Allele of a MYB Transcription Repressor Confers Multiple Disease Resistance in Maize.显示文摘Natural alleles controlling multiple disease resistances (MDR) are valuable for crop breeding. However, only one MDR gene have been cloned in maize, and molecular mechanisms of MDR are not clear. By map-based cloning, we have cloned a teosinte-derived allele of a resistance gene, Mexicana lesion mimic 1 (ZmMM1), which has a lesion mimic phenotype and confers resistance to northern leaf blight (NLB), gray leaf spot (GLS) and southern corn rust (SCR). Strong MDR conferred by the teosinte allele is linked with the polymorphisms in the 3' untranslated region of the ZmMM1 gene that cause increased accumulation of ZmMM1 protein. ZmMM1 acts as a transcription repressor and negatively regulates transcription of specific target genes including ZmMM1-target gene 3 (ZmMT3), which functions as a negative regulator of plant immunity and associated cell death. The successful isolation of the ZmMM1 resistance gene will help not only in developing broad-spectrum and durable disease resistance but also in understanding the molecular mechanisms underlying MDR. | Hongze Wang Jiabao Hou Pei Ye Long Hu Junshi Huang Zhikang Dai Bao Zhang Sha Dai Jiamin Que Haoxuan Min Gengshen Chen Yanbo Wang Min Jiang Yan Liang Lin Li Xuecai Zhang Zhibing Lai | 2021 | Molecular Plant2021，14，11： | 4 |
| 5 | Towards an optimization design of seepage control:A case study in dam engineering显示文摘High dams generally suffer from higher seepage risks in their foundations, and seepage control is an important technology for limiting the amount of leakage and improving the stability of the foundations. In this study, a procedure was proposed for optimization design of seepage control system in large-scale hydropower projects, which relies on sufficient characterization of site conditions and proper quantification of the performance of the seepage control system. The proposed procedure was applied to the design of seepage control system in the Mengdigou Hydropower Station consisting of a double-curvature arch dam201 m in height. An optimized layout of the seepage control system, including the extended length of grout curtain, the rows of grouting holes and the spacing of drainage holes, was suggested. The proposed procedure provides a guide with lower risk and higher confidence for performance assessment and optimization design of seepage control systems in high dam engineering. | LI Xing CHEN YiFeng HU Ran YANG ZhiBing | 2017 | Science China(Technological Sciences)2017，60，12： | 3 |
| 6 | Anti-disturbance attitude control of combined spacecraft with enhanced control allocation scheme显示文摘In this paper, we propose a novel anti-disturbance attitude control law for combined spacecraft with an improved closed-loop control allocation scheme. More specifically, a saturated approach is adopted to guarantee the global asymptotic stability under control input saturation.To enhance the robustness of the system, a nonlinear disturbance observer is constructed to compensate the disturbances caused by inertial parameter uncertainty and unmodeled dynamics. Next,the quadratic programming algorithm is used to obtain an optimal open-loop control allocation scheme, where both energy consumption and actuator saturation have been considered in the allocation of the virtual control command. Then, a modified closed-loop control allocation scheme is proposed to reduce the allocation error under the actuator uncertainty. Finally, stability analysis of the closed-loop system with the proposed allocation scheme is provided. Simulation results confirm the effectiveness of the proposed control scheme. | Jianzhong QIAO Zhibing LIU Wenshuo LI | 2018 | Chinese Journal of Aeronautics2018，31，8： | 3 |
| 7 | Space qualification mechanical tests of HTS filters for satellite application显示文摘High performance high-temperature superconducting (HTS) filters have been designed and constructed for satellite application. The filters are actually a superconducting integration of an 8-pole band-pass filter with an adjustable band-stop filter onto a single piece of LaAlO3 substrate (with dimension of 0.5×45×20 mm3). Typical results of the filters, i.e., Filters A (made by YBCO) & B (made by TBCCO) will be reported. The measured responses of Filter A showed excellent specifications, e.g., an insertion loss less than 0.1 dB, a return loss better than -22.5 dB in pass-band, band-edge steepness greater than 12 dB/MHz and out-of-band rejection at a certain band deeper than -110 dB. To satisfy the requirement of rocket launch and space operation, three filters of the above design have undergone mechanical environmental simulation tests for space qualification. Detailed analysis of the response curves of Filter B measured before and after the tests showed that no noticeable change in the per-formance can be found. All the filters passed the rigorous ground simulation tests, which is the first time in China for HTS devices and provided a solid foundation for satellite applications of high-temperature superconductors in the near future. | HUANG JianDong SUN Liang LI ShunZhou MENG QingDuan ZHANG Qiang LI Fei ZHANG XueQiang LI ChunGuang HE AiSheng LI Hong GU ChangZhi LUO Qiang SUN QinFen WANG XiaoLin SUN YiFan WANG ZhiBing WANG YunFei LUO Sheng HE YuSheng | 2007 | Chinese Science Bulletin2007，52，13： | 3 |
| 8 | Microwave triggered multifunctional nanoplatform for targeted photothermal-chemotherapy in castration-resistant prostate cancer显示文摘Lacking a precise targeting strategy,castration-resistant prostate cancer(CRPC)is still hard to be treat effectively.Exploring treatment options that can accurately target CPRC is an important issue with urgent need.In this study,a novel nanotechnologybased strategy had been developed for the precise target treatment of CRPC.By combining microwaves and photothermal therapy(PTT),this nanoplatform,cmHSP70-PL-AuNC-DOX,targets tumor tissues with outstanding precision and achieves better anti-tumor activity by simultaneously eliciting photothermal and chemotherapeutic effects.From nanotechnology,cmHSP70-modified and thermo-sensitive liposome-coated AuNC-DOX were prepared and used for CRPC-targeted photothermal ablation and chemotherapy.Doxorubicin(DOX)was selected as the chemotherapeutic agent for cytotoxicity.In terms of the curative scheme,prostate tissues were firstly pre-treated with microwaves to induce the expression of heat shock protein 70(HSP70)and its migration to the cell membrane,which was then targeted by HSP70 antibody(cmHSP70)coated on the nanoparticles to achieve accurate drug delivery.The nanoplatform then achieved precise ablation and controlled release of DOX under external near-infrared(NIR)irradiation.Through the implementation,the targeting,cell killing,and safety of this therapeutical strategy had been verified in vivo and in vitro.This work establishes an accurate,controllable,efficient,non-invasive,and safe treatment platform for targeting CRPC,provides a rational design for CRPC’s PTT,and offers new prospects for nanomedicines with great precision. | Pengyuan Liu Yajun Wu Xiaogang Xu Xudong Fan Chuan Sun Xiaojie Chen Jindan Xia Shiting Bai Li Qu Huasong Lu Jing Wu Jun Chen Ji-Gang Piao Zhibing Wu | 2023 | Nano Research2023，16，7： | 2 |
| 9 | A Hg(Ⅱ)-specific probe for imaging application in living systems and quantitative analysis in environmental/food samples显示文摘Mercury ions are highly toxic and can accumulate along food chains in water,soil,crops and animals.Effective detection of mercury ions in various media is of great significance for maintaining the ecological environment and protecting people's health.In this work,a mercury ions specific fluorescent probe was developed by a simple one-step reaction of commercial substrates of 4-chloro-7-nitro-2,1,3-benzoxadiazole and 1-(2-aminoethyl)-4-methylpiperazine.Investigation on sensing behavior showed that this probe had high sensitivity and selectivity towards mercury ions.Furthermore,this probe could be used as a tool to track the level of mercury ions in living system.In living cells,the probe with green emission emitted a bright red fluorescence when it was bound to mercury ions.In Arabidopsis thaliana,similar red emission could be detected from the root tip and stalk when A.thaliana was grown in culture medium containing mercury ions.The imaging in zebrafish showed that mercury ions were mainly concentrated in the stomach and head of zebrafish.Especially,this probe could be applied in quantitative analysis of mercury ions in tap water,green tea,sea shrimp and soil.This work provided a practical tool for the detection of mercury ions in living systems and quantitative analysis in real samples. | Guangjin Li Jiali Wang Dongyang Li Shenghua Liu Jun Yin Zhibing Lai Guangfu Yang | 2021 | Chinese Chemical Letters2021，32，4： | 2 |
| 10 | Mesoscale fabrication of a complex surface for integral impeller blades显示文摘 | Xibin WANG Tianfeng ZHOU Lijing XIE Li JIAO Zhibing LIU Zhiqiang LIANG Pei YAN | 2017 | Frontiers of Mechanical Engineering2017，12，1： | 2 |
| 11 | Double-lipase Catalyzed Synthesis of Kojic Dipalmitate in Organic Solvents显示文摘 | WANG Zhiyuan LUO Wen FU Junying LI Zhibing WANG Zhongming LU Pengmei | 2017 | Chemical Research in Chinese Universities2017，33，6： | 2 |
| 12 | Microinterface intensification in hydrogenation and air oxidation processes显示文摘Hydrogenations and air oxidations usually have low apparent reaction rate,generally controlled by mass transfer rate,and widely exist in the modern chemical manufacturing process.The key to increase the mass transfer rate is the reduction of the liquid film resistance 1/kLa.In this work,the original concept of microinterface intensification for mass transfer and then for these reactions has been proposed.We derived the regulation model and set up the mathematical calculation method of micron-scale gas-liquid interface structure on mass transfer and reaction,designed the mechanical energy exchange device that can produce gas-liquid microinterface system on a large scale,and established the OMIS system which is able on line to measure the diameter and distribution of millions of microbubbles,interface area a and mass transfer film thicknessδM,as well as developed a series of microinterface intensified reactor systems(MIRs)for the applications of hydrogenation and air oxidation processes.It is believed that this research will provide an up-to-date development for the intensification of hydrogenation and air oxidation reactions. | Hongliang Qian Hongzhou Tian Guoqiang Yang Gaodong Yang Lei Li Feng Zhang Zheng Zhou Weihua Huang Yufu Chen Zhibing Zhang | 2022 | Chinese Journal of Chemical Engineering2022，，10： | 2 |
| 13 | Thermal simulation experiment on the hydrocarbon regeneration of marine carbonate source rock显示文摘Hydrocarbon regeneration of marine carbonate source rock was simulated with thermal experiments in a laboratory. The results reveal that hydrocarbon regeneration does not simply continue the primary hydrocarbon generation process, and that, for marine carbonate source rock, discontinuous hydrocarbon generation differs greatly from the continuous generation. Several different features of hydrocarbon regeneration were observed in the experiments. First, the liquid hydrocarbon generation peak was always observed no matter what the initial maturity of the sample was. Moreover, the maturity and the liquid hydrocarbon yield corresponding to the peak varied with the sample’s initial maturity. Second, the hydrocarbon regeneration started earlier than the continuous one. In the experiments, the hydrocarbon could be re-generated when the sample maturity did not rise to any great extent. Third, the accumulative hydrocarbon-generating quantity during discontinuous generation was always more than that during continuous generation. And the hydrocarbon-generating quantity varied with the discontinuous generation history. Chemical kinetic analysis suggests that discontinuous hydrocarbon generation should not only be explained by the parallel reaction mechanism but also by the consecutive reaction mechanism which has been ignored in the traditional chemical kinetic model for continuous hydrocarbon generation. | LI HuiLi JIN ZhiJun HE ZhiLiang QIN JianZhong SHAO ZhiBing | 2007 | Chinese Science Bulletin2007，52，14： | 2 |
| 14 | The deposition of Au–Pt core–shell nanoparticles on reduced graphene oxide and their catalytic activity显示文摘 | Xiu Cui Shengnan Wu Scott Jungwirth Zhibing Chen Zhenghua Wang Lun Wang Yongxin Li | 2013 | Nanotechnology2013，，29： | 1 |
| 15 | Pervaporation of acetic acid/water mixures through carbon molecular sieve-filled PDMS membranes显示文摘 | Li Lei Xiao Zeyi Zhang Zhibing etal | 2004 | Chem Eng J2004，97，： | 1 |
| 16 | Pervaporation of acetic acid/water mixtures through carbon molecular sieve-filled PDMS membranes显示文摘 | Li Lei Xiao Zeyi Zhang Zhibing | 2004 | Chemical Engineering Journal2004，97，1： | 1 |
| 17 | Short-time behavior of the kinetic spherical model with long-ranged interactions显示文摘 | Yuan Chen Shuohong Guo Zhibing Li Aijun Ye | 2000 | The European Physical Journal B2000，，1： | 1 |
| 18 | Pervaporation of acetic acid water mixtures throughcarbon molecular sievefilled PDMS membranes显示文摘 | Li Lei Xiao Zeyi Zhang Zhibing | 2004 | Chem Eng J2004，97，： | 1 |
| 19 | 查看详情显示文摘 | Li Zhibing Xu Ningsheng Kreuzer H J | | 0，，： | 1 |
| 20 | Approach for vibration measurement based on laser frequency splitting technology 显示文摘 | ZHANG Yi DENG Zhibing LI Yan | 2000 | Measurement Science and Technology2000，11，11： | 1 |
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