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2594篇 您的检索式:作者名="Yu X C"
    题名 作者 年代 出处 被引量
1通过单细胞测序发现结肠癌双系起源的新型癌基因——SLC12A5显示文摘单细胞测序是一种为划定遗传关系和个性化癌症管理确认重要驱动基因的功能强大的工具。本研究运用单细胞测序分析1例结肠癌。群体遗传学分析确定了肿瘤群体中两个独立的克隆。作为早期致癌事件的大部分肿瘤克隆包含APC和TP 53基因突变,然而少数克隆却包含CDC27和PABPC1基因的优势突变。 APC和TP53基因突变在少数克隆中的缺失说明这两个克隆来自两个细胞起源。对于另外21例整个组织外显子测序并检查其体细胞突变的等位基因频谱,揭示了结肠癌克隆起源具有异质性。该研究确定SLC12A5基因的突变,显示其在单细胞水平的高频突变,然而群体水平上却呈低频突变。 SLC12A5突变的功能特征揭示其在结肠癌中潜在的致癌作用。该研究提供了结肠癌单细胞水平上第一个广谱外显子组的证据,支持结肠癌双系克隆起源以及人群中的低频突变可能发挥的重要促癌作用。Yu C Yu J Yao X 张俊 许春伟 张博 2014临床与实验病理学杂志2014,30,12:4
2Standard CMOS implementation of a novel, fully differential optoelectronic integrated receiver 显示文摘YU C L MAO L H XIAO X D 2009J of Optoelectronics Laser2009,20,4:1
3Probing of photocatalytic surface sites on SO2-4/TiO2 solid acids by in situ FT-IR spectroscopy and pyridine adsorption显示文摘 YU I C LIU P 2006Journal of Photochemistry and Photobiology A:Chemistry2006,179,:1
4Uniform Metal Nanotube Arrays by Multistep Template Replication and Electrodeposition显示文摘 Yu Y X Wang R M 2004Adv Mater2004,16,17:1
5Study of double layer rare earth metal conversion coating on aluminum alloy LY12显示文摘Yu X Cao C Yao Z 2001Corrosion Science2001,43,7:1
6Simultaneous determination of six phenolic constituents of danshen in human serum using liquid chromatography/tandem mass spectrometry 显示文摘Li X Yu C Cai Y Liu G 2005J Chromatography B2005,820,1:1
7Nitrobenzene hydrogenation with carbon nanotube-supported platinum catalyst under mild conditions 显示文摘LI C H YU Z X YAO K F 2005J Mole Catal A: Chem2005,226,1:1
8Factors affecting Agrobactcrium-mediated transformation and regeneration of sweet orange and citrange 显示文摘Yu C H Huang S Chen C X Deng Z A Ling P and Gmitter F O J 2002Plant Cell Tissue and Organ Culture2002,71,:1
9Digital coherent receiver for phase-modulated radio-over-fiber optical links显示文摘ZIBAR D YU X PEUCHERET C 2009IEEE Photonics Technology Letters2009,21,3:1
10显示文摘Cui Y B Liu C H Hu S Yu X 2011Solar Energy Materials & Solar Cells2011,95,4:1
11Sensitive and rapid detection of the new Delhi metallo-beta- lactamase gene by loop-mediated isothermal amplification 显示文摘Liu W Zou D Li Y Wang X He X Wei X Shao C Li X Shang W Yu K Liu D Li Y Guo J Yin Z Yuan J 2012J Clin Microbiol2012,50,5:1
12Determining socioeconomicdrivers of urban forest fragmentation with historical remote sens-ing images显示文摘Gong C F Yu S X Joesting H 2013Landscape and Urban Planning2013,117,9:1
13Effects of inoculation of PAH-degrading bacteria and arbuscular mycorrhizal fungi on responses Df ryegrass to phenanthrene and pyrene 显示文摘WU F Y YU X Z WU S C 2014International Journal of Phytoremediation2014,16,2:1
14A real time video fire flame and smoke detection algorithm 显示文摘Yu C Mei Z Zhang X 2013Procedia Engineering2013,62,:1
15Synthesis and character- ization of low crystalline waterborne polyurethane for potential application in water - based ink binder显示文摘Fang C Q Zhou X Yu Q 2014Progress in Organic Coatings2014,77,1:1
16Expression pattern genomic struc- ture, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata显示文摘XU W R YU Y H ZHOU Q DING J H DAI L M XIE X Q XU Y ZHANG C H WANG Y J 2011Journal of Experimen- tal Botany2011,62,8:1
17The Effects of Firm-initiated Clawback Provisions on Earnings Quality and Au- ditor Behavior显示文摘Chan L H Chen K C W Chen T Y Yu Y X 2012Journal of Accounting and Economics2012,,54:1
18The TIL commissioning and performance显示文摘X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang 2008Journal of Physics: Conference Series2008,,3:1
19Developmental, cytological and transcriptional analysis of autotetraploid Arabidopsis 显示文摘Li X D Yu E R Fan C C 2012Planta2012,236,2:1
20Mierostructure and Properties of TiAISiN Coatings Prepared by Hybrid PVD Technology 显示文摘Yu D H Wang C Y Cheng X L 2009Thin Solid Films2009,517,:1
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