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| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis显示文摘The heat shock transcription factors (HSFs) are the major heat shock factors regulating the heat stress response. They participate in regulating the expression of heat shock proteins (HSPs), which are critical in the protection against stress damage and many other important biological processes. Study of the HSF gene family is important for understanding the mechanism by which plants respond to stress. The completed genome sequences of rice (Oryza sativa) and Arabidopsis (Arabidopsis thaliana) constitute a valuable resource for comparative genomic analysis, as they are representatives of the two major evolutionary lineages within the angiosperms: the monocotyledons and the dicotyledons. The identification of phylogenetic relationships among HSF proteins in these species is a fundamental step to unravel the functionality of new and yet uncharacterized genes belonging to this family.In this study, the full complement of HSF genes in rice and Arabidopsis has probably been identified through the genome-wide scan. Phylogenetic analyses resulted in the identification of three major clusters of orthologous genes that contain members belonging to both species, which must have been represented in their common ancestor before the taxonomic splitting of the angiosperms. Further analysis of the phylogenetic tree reveals a possible dicot specific gene group. We also identified nine pairs of paralogs, as evidence for studies on the evolution history of rice HSF family and rice genome evolution. Expression data analysis indicates that HSF proteins are widely expressed in plants. These results provide a solid base for future functional genomic studies of the HSF gene family in rice and Arabidopsis. | Jingkang Guo Jian Wu Qian Ji Chao Wang Lei Luo Yi Yuan Yonghua Wang Jian Wang | 2008 | Journal of Genetics and Genomics2008，35，2： | 52 |
| 3 | Impacts and Utilization of Electric Vehicles Integration Into Power Systems显示文摘 | HUZechun SONG Yonghua XU Zhiwei LUO Zhuowei ZHAN Kaiqiao JIA Long | 2012 | 中国电机工程学报2012，32，4： | 49 |
| 4 | Mineralogical and geochemical features of sulfide chimneys from the 49°39′E hydrothermal field on the Southwest Indian Ridge and their geological inferences显示文摘During January–May in 2007,the Chinese research cruise DY115-19 discovered an active hydrothermal field at 49°39′E/37°47′S on the ultraslow spreading Southwest Indian Ridge (SWIR).This was also the first active hydrothermal field found along an ultraslow-spreading ridge.We analyzed mineralogical,textural and geochemical compositions of the sulfide chimneys obtained from the 49°39′E field.Chimney samples show a concentric mineral zone around the fluid channel.The mineral assemblages of the interiors consist mainly of chalcopyrite,with pyrite and sphalerite as minor constitunets.In the intermediate portion,pyrite becomes the dominant mineral,with chalcopyrite and sphalerite as minor constitunets.For the outer wall,the majority of minerals are pyrite and sphalerite,with few chalcopyrite.Towards the outer margin of the chimney wall,the mineral grains become small and irregular in shape gradually,while minerals within interstices are abundant.These features are similar to those chimney edifices found on the East Pacific Rise and Mid-Atlantic Ridge.The average contents of Cu,Fe and Zn in our chimney samples were 2.83 wt%,45.6 wt% and 3.28 wt%,respectively.The average Au and Ag contents were up to 2.0 ppm and 70.2 ppm respectively,higher than the massive sulfides from most hydrothermal fields along mid-ocean ridge.The rare earth elements geochemistry of the sulfide chimneys show a pattern distinctive from the sulfides recovered from typical hydrothermal fields along sedimentstarved mid-ocean ridge,with the enrichment of light rare earth elements but the weak,mostly negative,Eu anomaly.This is attributed to the distinct mineralization environment or fluid compositions in this area. | TAO ChunHui LI HuaiMing HUANG Wei HAN XiQiu WU GuangHai SU Xin ZHOU Ning LIN Jian HE YongHua ZHOU JianPing | 2011 | Chinese Science Bulletin2011，56，26： | 34 |
| 5 | Photovoltaic and Solar Power Forecasting for Smart Grid Energy Management显示文摘Due to the challenge of climate and energy crisis,renewable energy generation including solar generation has experienced significant growth.Increasingly high penetration level of photovoltaic(PV)generation arises in smart grid.Solar power is intermittent and variable,as the solar source at the ground level is highly dependent on cloud cover variability,atmospheric aerosol levels,and other atmosphere parameters.The inherent variability of large-scale solar generation introduces significant challenges to smart grid energy management.Accurate forecasting of solar power/irradiance is critical to secure economic operation of the smart grid.This paper provides a comprehensive review of the theoretical forecasting methodologies for both solar resource and PV power.Applications of solar forecasting in energy management of smart grid are also investigated in detail. | Can Wan Jian Zhao Yonghua Song Zhao Xu Jin Lin Zechun Hu | 2015 | CSEE Journal of Power and Energy Systems2015，1，4： | 29 |
| 6 | Genetic correction of p-thalassemia patient-specific iPS cells and its use in improving hemoglobin production in irradiated SCID mice显示文摘 | Yixuan Wang Chen-Guang Zheng Yonghua Jiang Jiqin Zhang Jiayu Chen Chao Yao Qingguo Zhao Sheng Liu Ke Chen Juan Du Ze Yang Shaorong Gao | 2012 | Cell Research2012，22，4： | 27 |
| 7 | Records of the East Asian winter monsoon from the mud area on the inner shelf of the East China Sea since the mid-Holocene显示文摘AMS14C dating and analysis of grain size,major elements and clay minerals were applied to Core MZ01 from the mud area on the inner shelf of the East China Sea.Based on the environmentally sensitive grain size,clay mineral and major element assemblages,the history of the East Asia winter monsoon since the mid-Holocene could be reconstructed.These three proxies,mean grain size(>9.71μm),chemical index of alteration(CIA)and ratio of smectite to kaolinite in particular,show similar fluctuation patterns. Furthermore,10 extreme values corresponding to the contemporary cooling events could be recognized since the mid-Holocene;these extreme values are likely to have been caused by the strengthening of the East Asia winter monsoon.The cooling events correlated well with the results of theδ18O curves of the Dunde ice core and GISP2,which therefore revealed a regional response to global climate change.Four stages of the East Asia winter monsoon were identified,i.e.8300-6300 a BP,strong and unstable;6300-3800 a BP,strong but stable;3800-1400 a BP,weak and unstable;after 1400 a BP,weak but stable. | LIU ShengFa SHI XueFa LIU YanGuang QIAO ShuQing YANG Gang FANG XiSheng WU YongHua LI ChaoXin LI XiaoYan ZHU AiMei GAO JingJing | 2010 | Chinese Science Bulletin2010，55，21： | 25 |
| 8 | Seafloor hydrothermal activity and polymetallic sulfide exploration on the southwest Indian ridge显示文摘Polymetallic sulfides have attracted more attentions,which are regarded as one of the potential seabed mineral resources for their high grade of precious metal elements such as Cu,Zn,Pb,Au,and Ag.Since2007,there are four China dayang cruises(CDCs)with eight legs totally,which have been carried out to investigate polymetallic sulfides on the southwest Indian ridge(SWIR),and eight hydrothermal vents have been found.In2011,the China Ocean Mineral Resources Research and Development Association(COMRA)and International Seabed Authority(ISA)signed a 15-year contract for exploration for polymetallic sulfides located on the SWIR between 46°S and 53°S.The area allocated to the COMRA is approximately 10,000 km2.In this paper,we review the recent research advances about hydrothermal activity of the SWIR by the CDCs.As for the sulfides exploration in the future,some aspects should be emphasized,such as the controlling factors of sulfide mineralization on the SWIR,prospecting methods of inactive and buried sulfide deposits,sulfides resources assessment method,and the nearbottom sulfides exploration technology systems. | Chunhui Tao Huaiming Li Xiaobing Jin Jianping Zhou Tao Wu Yonghua He Xianming Deng Chunhua Gu Guoyin Zhang Weiyong Liu | 2014 | Chinese Science Bulletin2014，59，19： | 25 |
| 9 | An Internet of Energy Things Based on Wireless LPWAN显示文摘 | Yonghua Song Jin Lin Ming Tang Shufeng Dong | 2017 | Engineering2017，3，4： | 24 |
| 10 | Genetic analysis of 'all-fish' growth hormone gene transferred carp (Cyprinus carpio L.) and its F_1 generation显示文摘Recornbinant 'all-fish' growth hormone gene (GH) was microinjected into the fertilized eggs of carp. A comparison between the growth traits of transgenics and non-transgenics was carried out, and the transgenic individuals with significant 'fast-growing' effect were successfully gained. A comparison on the reproductivities was also given out between the transgenics and their non-transgenic siblings, and showed that the reproductive capacity of transgenics was substantially equivalent to those of the non-transgenics. On the other hand, the genetic separation and the characteristic distribution of the FI generation were genetically analyzed, which gave solid evidence for the hypothesis that 2-3 chromosomes are integrated with trans-gene. In addition, the distinct biological effects for multi-site-integrated transgenes were further discussed. The present study opens a door for the breeding of 'fast-growing' transgenic fish. | WANG Yaping, HU Wei, WU Gang,SUN Yonghua, CHEN Shangping, ZHANG Fuying,ZHU Zuoyan, FENG Jianxin & ZHANG Xirui1. State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China 2. Henan Institute of Aquaculture, Zhengzhou 450044, China | 2001 | Chinese Science Bulletin2001，46，14： | 23 |
| 11 | Interface Migration between Martensite and Austenite during Quenching and Partitioning (Q&P) Process显示文摘Fe-0.2C-l.5Si-l.67Mn 钢受到熄灭并且划分(Q&P ) 进程,和在在提高的划分温度的马氏体和奥氏体之间的接口移植被观察。接口迁居在 constrainedparaequilibrium (用户终端设备) 被排除模型。基于“端点”由用户终端设备模型预言接口移植的热力学的条件被分析,也就是说,在在铁酸盐(martenisite ) 和奥氏体的铁的化学势的差别生产铁原子的驱动力从一个阶段移居到另外的阶段。另外,接口迁居罐头改变奥氏体部分;作为结果,在划分温度的奥氏体部分可能在通过接口移植熄灭温度比那高,但是这现象不能被用户终端设备模型解释。 | Ning ZHONG Xiaodong WANG Yonghua RONG Li WANG | 2006 | Journal of Materials Science & Technology2006，22，6： | 19 |
| 12 | Crustal and uppermost mantle structure of SE Tibetan plateau from Rayleigh-wave group-velocity measurements显示文摘A shear-wave velocity model of the crust and uppermost mantle beneath the SE Tibetan plateau was derived by inverting Rayleigh-wave group-velocity measurements of periods between 10 and 70 s. Rayleigh-wave group-velocity dispersions along more than 3,000 interstation paths were measured based on analysis of teleseismic waveform data recorded by temporary seismic stations. These observations were then utilized to construct2 D group-velocity maps in the period range of 10–70 s.The new group-velocity maps have an enhanced resolution compared with previous global and regional group-velocity models in this region because of the denser and more uniform data coverage. The lateral resolution across the region is about 0.5° for the periods used in this study. Local dispersion curves were then inverted for a 3D shear-wave velocity model of the region by applying a linear inversion scheme. Our 3D shear-wave model confirms the presence of low-velocity zones(LVZs) in the crust beneath the northern part of this region. Our imaging shows that the upper-middle crustal LVZ beneath the Tengchong region is isolated from these LVZs beneath the eastern and northern part of this region. The upper–middle crustal LVZ may be regarded as evidence of a magma chamber in the crust beneath the Tengchong Volcanoes. Our model also reveals a slow lithospheric structure beneath Tengchong and a fast shield-like mantle beneath the stable Yangtze block. | Yonghua Li Jiatie Pan Qingju Wu Zhifeng Ding | 2014 | Earthquake Science2014，27，4： | 19 |
| 13 | Ergodic degrees for continuous-time Markov chains显示文摘This paper studies the existence of the higher orders deviation matrices for continuous time Markov chains by the moments for the hitting times. An estimate of the polynomial convergence rates for the transition matrix to the stationary measure is obtained. Finally, the explicit formulas for birth-death processes are presented. | MAO Yonghua | 2004 | Science China Mathematics2004，47，2： | 18 |
| 14 | EXPERIMENTAL AND NUMERICAL STUDIES ON DYNAMIC COMPRESSIVE BEHAVIOR OF REACTIVE POWDER CONCRETES显示文摘Split Hopkinson pressure bar (SHPB) technique is used to determine the dynamic strength of reactive powder concretes (RPCs) with different steel-fiber contents. Two types of pulse shapers with different thicknesses are considered to reduce the high-frequency-oscillation effect and achieve a nearly constant strain rate over a certain deformation range. It is known that the compressive strength of concrete-like materials is hydrostatic-stress-dependent, and the apparent dynamic strength enhancement comes from both the effects of the hydrostatic stress and strain rate. In order to differentiate them, numerical method is used to calculate the contribution of the hydrostatic stress, and then the genuine strain-rate effect on dynamic compressive strength of RPCs is determined. In addition, the effect of steel-fibers on dynamic strength and failure mode of RPCs is discussed. | Yonghua Wang Zhengdao Wang Xiaoyan Liang Minzhe An | 2008 | Acta Mechanica Solida Sinica2008，21，5： | 18 |
| 15 | A long-term Global LAnd Surface Satellite(GLASS)data-set for environmental studies显示文摘Recently,five Global LAnd Surface Satellite(GLASS)products have been released:leaf area index(LAI),shortwave broadband albedo,longwave broadband emissivity,incident short radiation,and photosynthetically active radiation(PAR).The first three products cover the years 19822012(LAI)and 19812010(albedo and emissivity)at 15 km and 8-day resolutions,and the last two radiation products span the period 20082010 at 5 km and 3-h resolutions.These products have been evaluated and validated,and the preliminary results indicate that they are of higher quality and accuracy than the existing products.In particular,the first three products have much longer time series,and are therefore highly suitable for various environmental studies.This paper outlines the algorithms,product characteristics,preliminary validation results,potential applications and some examples of initial analysis of these products. | Shunlin Liang Xiang Zhao Suhong Liu Wenping Yuan Xiao Cheng Zhiqiang Xiao Xiaotong Zhang Qiang Liu Jie Cheng Hairong Tang Yonghua Qu Yancheng Bo Ying Qu Huazhong Ren Kai Yu John Townshend | 2013 | International Journal of Digital Earth2013，6，S01： | 16 |
| 16 | Generation of induced pluripotent stem cells from human β-thalassemia fibroblast cells显示文摘 | Yixuan Wang Yonghua Jiang Sheng Liu Xiaofang Sun Shaorong Gao | 2009 | Cell Research2009，19，9： | 16 |
| 17 | Modeling and Operation of the Power-to-Gas System for Renewables Integration: A Review显示文摘Power-to-Gas(P2G)plays an important role in enhancing large-scale renewable energy integration in power systems.As an emerging inter-disciplinary subject,P2G technology requires knowledge in electrochemistry,electrical engineering,thermodynamic engineering,chemical engineering and system engineering.Aiming at P2G modeling and operational problems concerning the research field of power systems and the energy internet,this paper briefly reviews the main technologies and application potentials of the P2G system,and makes systematic summaries of major progresses related to P2G’s integration into the power grid in a bottom-top manner,including the modeling of high/room-temperature electrolysis cells,steady-state/dynamic optimization control of the P2G system,P2G’s integrated model and operational strategies at the grid level.In the final part of this paper,suggestions are put forward on future research directions of P2G systems from the aspects of modeling and operational optimization. | Xuetao Xing Jin Lin Yonghua Song You Zhou Shujun Mu Qiang Hu | 2018 | CSEE Journal of Power and Energy Systems2018，4，2： | 15 |
| 18 | Focal depths for moderate-sized aftershocks of the Wenchuan M_S8.0 earthquake and their implications显示文摘Sliding-window cross-correlation method is firstly adopted to identify sPn phase, and to constrain focal depth from regional seismograms, by measuring the time separation between sPn and Pn phases. We present the focal depths of the 17 moderate-sized aftershocks (MS≥5.0) of the Wenchuan MS8.0 earth-quake, using the data recorded by the regional seismic broadband networks of Shaanxi, Qinghai, Gansu, Yunnan and Sichuan. Our results show focal depths of aftershocks range from 8 to 20 km, and tend to cluster at two average depths, separate at 32.5°N, i.e., 11 km to the south and 17 km to the north, indicating that these aftershocks are origin of upper-to-middle crust. Combined with other results, we suggest that the Longmenshan fault is not a through-going crustal fault and the Pingwu-Qingchuan fault may be not the northward extension of the Longmenshan thrust fault. | ZHANG RuiQing WU QingJu LI YongHua DING ZhiFeng ZENG RongSheng | 2008 | Science China Earth Sciences2008，51，12： | 14 |
| 19 | Quaternary glacier development and the relationship between the climate change and tectonic uplift in the Helan Mountain显示文摘孤立拉长 Helan 山脉山岳的 NE-SW,分开从 Tenggeli 沙漠的 Ordos 高原的适度的草地,是在西方中国学习冰河发展的一个关键位置以及气候的联合条件随着变化构造高举。冰川的地形和存款包括冰斗,山峰,刀口山脉,侧面的冰碛,和终端冰碛在 Helan 山的中间的部分在 2800 m a.s.l 上面散布。这分布显示这曾经是 glaciated 在期间晚第四级。形态学特征证明形成事件的风景的一个清楚的序列发生在整个 Helan 山。实验室光学地刺激了光(OSL ) 和标明日期的加速器团 spectrometry 放射性碳(AMS 14C ) 结果显示冰川的进展的迟了的历史。在 Helan 山的中间的部分的迟了的更新世冰河进展了接近他们的位置至少四次,并且冰川的序列能作为最后一个冰川的周期的中间的阶段被分配(MIS3b, 43.2 ????????? ′ ? 錸? 錸?@ | ZHANG Wei HE MingYue LI YongHua CUI ZhiJiu WANG ZhiLin YU Yang | 2012 | Chinese Science Bulletin2012，57，34： | 14 |
| 20 | Seeker optimization algorithm:a novel stochastic search algorithm for global numerical optimization显示文摘A novel heuristic search algorithm called seeker optimization algorithm(SOA) is proposed for the real-parameter optimization.The proposed SOA is based on simulating the act of human searching.In the SOA,search direction is based on empirical gradients by evaluating the response to the position changes,while step length is based on uncertainty reasoning by using a simple fuzzy rule.The effectiveness of the SOA is evaluated by using a challenging set of typically complex functions in comparison to differential evolution(DE) and three modified particle swarm optimization(PSO) algorithms.The simulation results show that the performance of the SOA is superior or comparable to that of the other algorithms. | Chaohua Dai Weirong Chen Yonghua Song Yunfang Zhu | 2010 | Journal of Systems Engineering and Electronics2010，21，2： | 13 |
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