|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Versatile Functionalization of Carbon Nanomaterials by Ferrate(Ⅵ)显示文摘As a high-valent iron compound with Fe in the highest accessible oxidation state,ferrate(VI)brings unique opportunities for a number of areas where chemical oxidation is essential.Recently,it is emerging as a novel oxidizing agent for materials chemistry,especially for the oxidation of carbon materials.However,the reported reactivity in liquid phase(H2SO4 medium)is confusing,which ranges from aggressive to moderate,and even incompetent.Meanwhile,the solid-state reactivity underlying the“dry”chemistry of ferrate(VI)remains poorly understood.Herein,we scrutinize the reactivity of K2FeO4 using fullerene C60 and various nanocarbons as substrates.The results unravel a modest reactivity in liquid phase that only oxidizes the active defects on carbon surface and a powerful oxidizing ability in solid state that can open the inert C=C bonds in carbon lattice.We also discuss respective benefit and limitation of the wet and dry approaches.Our work provides a rational understanding on the oxidizing ability of ferrate(VI)and can guide its application in functionalization/transformation of carbons and also other kinds of materials. | Ying Zhou Zhao‑Yang Zhang Xianhui Huang Jiantong Li Tao Li | 2020 | Nano-Micro Letters2020，12，3： | 1 |
| 2 | Advances and Applications of Brain Organoids显示文摘Understanding the fundamental processes of human brain development and diseases is of great importance for our health.However,existing research models such as non-human primate and mouse models remain limited due to their developmental discrepancies compared with humans.Over the past years,an emerging model,the“brain organoid”integrated from human pluripotent stem cells,has been developed to mimic developmental processes of the human brain and disease-associated phenotypes to some extent,making it possible to better understand the complex structures and functions of the human brain.In this review,we summarize recent advances in brain organoid technologies and their applications in brain development and diseases,including neurodevelopmental,neurodegenerative,psychiatric diseases,and brain tumors.Finally,we also discuss current limitations and the potential of brain organoids. | Yang Li Peng‑Ming Zeng Jian Wu Zhen‑Ge Luo | 2023 | Neuroscience Bulletin2023，39，11： | 0 |
| 3 | METTL14 upregulates m6A modification of pri‑miR‑141 inhibiting ZEB1 to promote proliferation and inflammation of lung fibroblasts显示文摘Objective: To explore whether METTL14 is involved in regulating the fibroblast proliferation and inflammatory cytokine secretion by regulating the m6A modification of pri‑miR‑141. Methods: MRC‑5 cells were transfected via METTL14 overexpression lentivirus to increase METTL14 expression. Levels of METTL14 and ZEB1 were measured by qPCR and western blot. The effect of METTL14 on MRC‑5 proliferation and apoptosis was determined by CCK‑8 and flow cytometry, respectively. The ELISA kits of IL‑2, IL6 and TNF‑α were used to detect the effect of METTL14 on MRC‑5 inflammatory secretion. m6A modification site on pri‑miR‑141 was detected by meRIP. The binding site between pri‑miR‑141 and METTL14 was determined by RIP. Results: We successfully upregulated METTL14 expression in MRC‑5 cells. Elevated METTL14 promoted MRC‑5 cell proliferation, suppressed its apoptosis and promoted inflammatory factors secretion in MRC‑5 cells. pri‑miR‑141 had m6A modification sites. pri‑miR‑141 can directly bind to METTL14. METTL14 upregulation increased miR‑141 while suppressed ZEB1 expression. Conclusion: METTL14 can promote the expression of miR‑141 by increasing the m6A modification site of pri‑miR‑141, and inhibit ZEB1, thereby promoting the proliferation of fibroblasts and the secretion of inflammatory factors. | YANG Yi‑xiu CHEN Jie LI Quan‑ni LIN Mei DING Yi‑peng | 2023 | Journal of Hainan Medical University2023，29，2： | 0 |
| 4 | Harnessing the unique features of MXenes for sulfur cathodes显示文摘Lithium-sulfur(Li-S)battery,as an emerging rechargeable energy-storage system,sparks intensive research enthusiasm owing to its high theoretical energy density.However,the sulfur cathode undergoes the low coulombic efficiency,poor rate and cycling performance,caused by the polysulfides shuttle,low conductivity and sluggish redox kinetics.To address the above issues,various hybrid sulfur cathodes are developed based on two-dimensional(2D)materials.Recently,2D transition metal carbides and nitrides(MXenes)are receiving intensive interest as matrix materials for sulfur cathodes owing to their favorable properties,such as superior electrical conductivity,abundant active sites and adjustable surface functional groups.In this review,we mainly summarize the development of novel hybrid sulfur cathodes by taking advantage of unique properties of MXenes.The different roles MXenes played in sulfur cathodes,including facilitating the electron transfer,tuning the adsorption of polysulfides and catalyzing polysulfides conversion,are well discussed.Finally,we propose the future strategies on the rational design of MXene-based sulfur cathodes with high performances. | Zhen‑Jiang Cao Yong‑Zheng Zhang Yang‑Lan‑Sen Cui Bin Li Shu‑Bin Yang | 2020 | Tungsten2020，2，2： | 0 |
| 5 | Evaluation of tungsten interatomic potentials for radiation damage simulations显示文摘The structure and properties of materials under neutron irradiation are an important basis in future fusion reactors.In the absence of fusion neutron sources for irradiation experiments,it is increasingly important and urgent to carry out neutron irradiation simulations on fusion reactor materials and then establish complete databases of defect properties and collisional cascades,where the first and foremost step is to select suitable interatomic potentials for atomistic-level simulations.In this work,six typic interatomic potentials for tungsten(W)are evaluated and reviewed systematically for radiation damage simulations.The relative lattice stability and elastic constants of bulk W are considered first with those potentials;then,the properties of point defects and defect clusters at interstitial sites and vacancies are obtained by molecular statics/dynam-ics simulations.The formation energies of interstitial/vacancy clusters,1/2<111>and<100>dislocation loops in W and the threshold displacement energies along different directions are also determined.In addition,the extended defects are further investigated,such as free surfaces and the energy profiles of 1/2<111>{110}and 1/2<111>{112}stacking faults.The current results provide a reference for selecting W potentials to simulate the radiation damage. | Li‑Xia Liu Xiao‑Chun Li Yang‑Chun Chen Wang‑Yu Hu Guang‑Nan Luo Fei Gao Hui‑Qiu Deng | 2020 | Tungsten2020，2，1： | 4 |
| 6 | Performance of compact plastic scintillator strips with wavelength shifting fibers using a photomultiplier tube or silicon photomultiplier readout显示文摘This study presents the design and performance results for compact plastic scintillator strips using a wavelength shifting fiber(WLS-fiber)readout with dimensions of 0.1 m×0.02 m×2 m.This approach was evaluated as a candidate for a cosmic-ray muon detector for the Taishan Antineutrino Observatory(JUNO-TAO).The strips coupled with 3-inch photomultiplier tubes(PMTs)were measured and compared between the single-end and double-end readout options.Additionally,a strip using the double-end option coupling with a silicon photomultiplier(SiPM)was further evaluated and compared with the results obtained using PMTs.The performance of the strips was determined by a detailed survey along their length with a cosmicray muon after detailed characterization of the 3-inch PMTs and SiPMs.The proposed design employing a compact plastic scintillator strip with WLS-fiber coupling to a SiPM provides a good choice for cosmic-ray muon veto detectors,particularly when detector dimensions must be limited. | Min Li Zhi‑Min Wang Cai‑Mei Liu Pei‑Zhi Lu Guang Luo Yuen‑Keung Hor Jin‑Chang Liu Chang‑Gen Yang | 2023 | Nuclear Science and Techniques2023，34，2： | 3 |
| 7 | Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis显示文摘Viral infections contribute to approximately 12%of cancers worldwide,with the vast majority occurring in developing countries and areas.Two DNA viruses,Epstein-Barr virus(EBV) and human papillomavirus(HPV),are associated with38%of all virus-associated cancers.The probability of one patient infected with these two distinct types of viruses is increasing.Here,we summarize the co-infection of EBV and HPV in human malignancies and address the possible mechanisms for the co-infection of EBV and HPV during tumorigenesis. | Ying Shi Song‑Ling Peng Li‑Fang Yang Xue Chen Yong‑Guang Tao Ya Cao | 2016 | Chinese Journal of Cancer2016，35，3： | 3 |
| 8 | 3D printing of hydroxyapatite/tricalcium phosphate scaffold with hierarchical porous structure for bone regeneration显示文摘Three-dimensional(3D)-printed scaffolds have attracted considerable attention in recent years as they provide a suitable environment for bone cell tissue regeneration and can be customized in shape.Among many other challenges,the material composition and geometric structure have major impacts on the performance of scaffolds.Hydroxyapatite and tricalcium phosphate(HA/TCP),as the major constituents of natural bone and teeth,possess attractive biological properties and are widely used in bone scaffold fabrication.Many fabrication methods have been investigated in attempts to achieve HA/TCP scaffolds with microporous structure enabling cell growth and nutrient transport.However,current 3D printing methods can only achieve the fabrication of HA/TCP scaffolds with certain range of microporous structure.To overcome this challenge,we developed a slurry-based microscale mask image projection stereolithography,allowing us to form a HA/TCP-based photocurable suspension with complex geometry including biomimetic features and hierarchical porosity.Here,the curing performance and physical properties of the HA/TCP suspension were investigated,and a circular movement process for the fabrication of highly viscous HA/TCP suspension was developed.Based on these investigations,the scaffold composition was optimized.We determined that a 30 wt%HA/TCP scaffold with biomimetic hierarchical structure exhibited superior mechanical properties and porosity.Cell proliferation was investigated in vitro,and the surgery was conducted in a nude mouse in vivo model of long bone with cranial neural crest cells and bone marrow mesenchymal stem cells.The results showed our 3D-printed HA/TCP scaffold with biomimetic hierarchical structure is biocompatible and has sufficient mechanical strength for surgery. | Xiangjia Li Yuan Yuan Luyang Liu Yuen‑Shan Leung Yiyu Chen Yuxing Guo Yang Chai Yong Chen | 2020 | Bio-Design and Manufacturing2020，3，1： | 3 |
| 9 | Multiscale Failure Mechanism Analysis of SiC Fiber‑Reinforced TC17 Composite Subjected to Transverse Tensile Loading at Elevated Temperature显示文摘This study presents a multiscale method to evaluate the transverse tensile strength and failure mechanism of SiC_(f)/TC17 cruciform specimen machined from a large-size ring.The mechanical properties and failure of the specimen were evaluated through a macroscale model under transverse tensile loading at 200°C.A mesoscale model was developed to analyze the transverse tensile behavior and failure of the composite specimen.Interfacial debonding,plastic deformation of matrix and cladding,and damage to the composite core were incorporated into the mesoscopic and macroscopic models.The stress–strain curves and fracture modes obtained from the numerical simulation showed good agreement with the experimental curves,acoustic emission test results,and fracture morphology.The simulation results suggested that the damage to the central region interface and the plastic deformation of the matrix initiated first and propagated outwards.Subsequently,the interfacial failure,matrix failure,and formation of macro-crack developed,which led to the crack of the titanium matrix composite core.Finally,cladding was plastically deformed and crack developed,which led to the severe failure of the cruciform specimen. | Qiu‑Yue Jia Yu‑Min Wang Xu Zhang Guo‑Xing Zhang Qing Yang Li‑Na Yang Xu Kong Xiao‑Fang Li Rui Yang | 2023 | Acta Metallurgica Sinica(English Letters)2023，36，6： | 1 |
| 10 | A review on recent progress of thermionic cathode显示文摘As the performance of vacuum electron devices is essentially governed by the properties of their cathodes,developing efficient and durable thermionic cathode is necessary and highly desired to meet the boosting requirements of vacuum electron devices.This review summarized the progress made in the past decades with a detailed discussion on the occurred various thermionic cathodes and their features,and the understandings of the correlation between the emission properties and the composition,where structure and synthesis method are well illustrated.Furthermore,dispenser cathodes with novel structures and emission mechanism are highlighted to indicate the recent achievement in this area of research,and Sc-cathode is considered as a promising candidate for the next-generation vacuum electron devices due to the greatly improved efficiency.However,challenges still exist to meet the ever-growing demands of thermionic cathode with collaborative requirement of high performance,easy fabrication and inadequate reproducibility. | Jun‑Yan Gao Yun‑Fei Yang Xiao‑Ke Zhang Shi‑Lei Li Peng Hu Jin‑Shu Wang | 2020 | Tungsten2020，2，3： | 1 |
| 11 | Interactions between long interpregnancy interval and advanced maternal age on neonatal outcomes显示文摘Background After the implementation of the universal two-child policy in China,it was more frequent to have long interpregnancy intervals(IPIs)and advanced maternal age.However,the interactions between long IPIs and advanced maternal age on neonatal outcomes are unknown.Methods The study subjects of this historical cohort study were multiparas with singleton live births between October 1st,2015,and October 31st,2020.IPI was defned as the interval between delivery and conception of the subsequent pregnancy.Logistic regression models were used to calculate adjusted odds ratios(aORs)and 95%confdence intervals(CIs)of the risks of preterm birth(PTB),low birth weight(LBW),small for gestation age,and 1-min Apgar score≤7 in diferent IPI groups.Relative excess risk due to interaction(RERI)was used to evaluate the additive interaction between long IPIs and advanced maternal age.Results Compared with the 24≤IPI≤59 months group,the long IPI group(IPI≥60 months)was associated with a higher risk of PTB(aOR,1.27;95%CI:1.07–1.50),LBW(aOR,1.32;95%CI 1.08–1.61),and one-minute Apgar score≤7(aOR,1.46;95%CI 1.07–1.98).Negative additive interactions(all RERIs<0)existed between long IPIs and advanced maternal age for these neonatal outcomes.Meanwhile,IPI<12 months was also associated with PTB(aOR,1.51;95%CI 1.13–2.01),LBW(aOR,1.50;95%CI 1.09–2.07),and 1-min Apgar score≤7(aOR,1.93;95%CI 1.23–3.04).Conclusions Both short and long IPIs are associated with an increased risk of adverse neonatal outcomes.Appropriate IPI should be recommended to women planning to become pregnant again.In addition,better antenatal care might be taken to balance the inferiority of advanced maternal age and to improve neonatal outcomes. | Yan Ma Hua Fu Yang li Zheng‑Rong Bao Wen‑Bin Dong Xiao‑Ping Lei | 2023 | World Journal of Pediatrics2023，19，12： | 0 |
| 12 | Optimization method of Hadamard coding plate inγ‑ray computational ghost imaging显示文摘Owing to the constraints on the fabrication ofγ-ray coding plates with many pixels,few studies have been carried out onγ-ray computational ghost imaging.Thus,the development of coding plates with fewer pixels is essential to achieveγ-ray computational ghost imaging.Based on the regional similarity between Hadamard subcoding plates,this study presents an optimization method to reduce the number of pixels of Hadamard coding plates.First,a moving distance matrix was obtained to describe the regional similarity quantitatively.Second,based on the matrix,we used two ant colony optimization arrangement algorithms to maximize the reuse of pixels in the regional similarity area and obtain new compressed coding plates.With full sampling,these two algorithms improved the pixel utilization of the coding plate,and the compression ratio values were 54.2%and 58.9%,respectively.In addition,three undersampled sequences(the Harr,Russian dolls,and cake-cutting sequences)with different sampling rates were tested and discussed.With different sampling rates,our method reduced the number of pixels of all three sequences,especially for the Russian dolls and cake-cutting sequences.Therefore,our method can reduce the number of pixels,manufacturing cost,and difficulty of the coding plate,which is beneficial for the implementation and application ofγ-ray computational ghost imaging. | Zhi Zhou San‑Gang Li Qing‑Shan Tan Li Yang Ming‑Zhe Liu Ming Wang Lei Wang Yi Cheng | 2023 | Nuclear Science and Techniques2023，34，1： | 0 |
| 13 | Mesh‑free semi‑quantitative variance underestimation elimination method in Monte Caro algorithm显示文摘The inter-cycle correlation of fission source distributions(FSDs)in the Monte Carlo power iteration process results in variance underestimation of tallied physical quantities,especially in large local tallies.This study provides a mesh-free semiquantitative variance underestimation elimination method to obtain a credible confidence interval for the tallied results.This method comprises two procedures:Estimation and Elimination.The FSD inter-cycle correlation length is estimated in the Estimation procedure using the Sliced Wasserstein distance algorithm.The batch method was then used in the elimination procedure.The FSD inter-cycle correlation length was proved to be the optimum batch length to eliminate the variance underestimation problem.We exemplified this method using the OECD sphere array model and 3D PWR BEAVRS model.The results showed that the average variance underestimation ratios of local tallies declined from 37 to 87%to within±5%in these models. | Peng‑Fei Shen Xiao‑Dong Huo Ze‑Guang Li Zeng Shao Hai‑Feng Yang Peng Zhang Kan Wang | 2023 | Nuclear Science and Techniques2023，34，1： | 0 |
| 14 | Genetic Distributions of 22 Short Tandem Repeat Loci in 760 Unrelated Tibet,Uygur,and Mongolia Individuals from China显示文摘In recent years,paternity testing in ethnic minority areas in China increases rapidly.However,the number of existing genetic markers does not meet the needs.The objective is to study the information of 22 genetic markers in Mongolian,Tibetan,and Uygur Nationality.The genetic polymorphism of 22 short tandem repeat(STR)loci(D10S1435,D11S2368,D12S391,D13S325,D14S608,D15S659,D16S539,D17S1290,D18S535,D19S253,D1S1656,D20S470,D21S1270,D22GATA198B05,D2S1338,D3S3045,D4S2366,D5S2500,D6S477,D7S3048,D8S1132,and D9S925)was estimated in 259 Uyghur,251 Tibetan,and 250 Inner Mongolian individuals from China who were all unrelated.Allele frequencies and forensic parameters were evaluated.The Hardy-Weinberg equilibrium(HWE)of each locus and the linkage disequilibrium(LD)for all pairwise STR loci were tested.Additionally,the Nei's genetic distance was used to estimate the genetic heterogeneity between Tibetan,Uyghur,Mongolian,Chinese Northern Han and Chinese Li population.The 22 loci showed high genetic polymorphism in the three ethnic groups.An exact test for the genotype distribution of the markers showed no significant deviation from HWE.These 22 STR loci could be treated as independent loci at the population level in these three ethnic groups.Relatively short genetic distances were found between the Mongolian and Han and Uygur populations.The 22 loci had no LD in the three ethnic groups and showed high heterozygosity,providing genetic information and forensic statistics for the Uyghur,Tibetan,and Inner Mongolian groups.These 22 STR loci will be useful for identification and kinship analysis in these three populations in China. | Ya‑Ran Yang Jian Yang Feng Li Yong‑Zai Wang Zai‑Liang Yu Jiang‑Wei Yan Di Lu | 2019 | Journal of Forensic Science and Medicine2019，5，2： | 0 |
| 15 | Progress of photonuclear cross sections for medical radioisotope production at the SLEGS energy domain显示文摘Photonuclear reactions using a laser Compton scattering(LCS)gamma source provide a new method for producing radioisotopes for medical applications.Compared with the conventional method,this method has the advantages of a high specific activity and less heat.Initiated by the Shanghai Laser Electron Gamma Source(SLEGS),we conducted a survey of potential photonuclear reactions,(γ,n),(γ,p),and(γ,γ')whose cross sections can be measured at SLEGS by summarising the experimental progress.In general,the data are rare and occasionally inconsistent.Therefore,theoretical calculations are often used to evaluate the production of medical radioisotopes.Subsequently,we verified the model uncertainties of the widely used reaction code TALYS-1.96,using the experimental data of the^(100)Mo(γ,n)^(99)Mo,^(65)Cu(γ,n)^(64)Cu,and^(68)Zn(γ,p)^(67)Cu reactions. | Xuan Pang Bao‑Hua Sun Li‑Hua Zhu Guang‑Hong Lu Hong‑Bo Zhou Dong Yang | 2023 | Nuclear Science and Techniques2023，34，12： | 0 |
| 16 | Efficiently Writing Bragg Grating in High-Birefringence Elliptical Microfiber for Label-Free Immunosensing with Temperature Compensation显示文摘Immunosensor is a powerful tool in healthcare and clinic,food and drug industry,and environmental protection.Label-free fiber-optic immunosensors have shown a myriad of advantages,such as high sensitivity,anti-electromagnetic interference,and afield measurement via the fiber network.However,the fiber-optic based sensor may bear the temperature cross-talk,especially under the warming condition for bio-activating the immune molecules.In this study,we proposed a highly birefringent microfiber Bragg grating for immunosensing with the temperature-compensation.The birefringent microfiber was drawn from the elliptical cladding multimode fiber that was ablated by the CO2 laser.The considerably large energy overlap region offered by the original multimode fiber favored the efficient inscription of FBG with high reflectivity.The dual reso-nances derived by the orthogonal polarization states presented similar temperature responsivities but significantly different ambient refractive index sensitivities,allowing the temperature-compensational RI sensing.The human immunoglobulin G(IgG)molecules were anchored on the surface of the microfiber grating probe by the covalent functionalization technique to enable the specific detection of the anti-IgG molecule.The proposed method promises a high-efficiency and low-cost design for the microfiber Bragg grating-based biosensor without being subjected to the temperature cross-sensitivity. | Peng Xiao Zhiyuan Xu Deming Hu Lili Liang Lipeng Sun Jie Li Yang Ran Bai‑Ou Guan | 2021 | Advanced Fiber Materials2021，3，5： | 0 |
| 17 | Effect of Cx32 over‑expression on cell proliferation, migration, and invasion of hepatocellular carcinoma cell line Huh7 and its mechanism显示文摘Objective: To explore the effect of connexin 32 (Cx32) on the cell proliferation, migration, invasion of human hepatocellular carcinoma (HCC) cell line Huh7 and its mechanism. Methods: Firstly, bioinformatics techniques were used to analyze the difference in expression of Cx32 between HCC tissues and normal liver tissues, and the relationship between Cx32 expression and important clinicopathological features of HCC was also explored. Subsequently, Cx32 expression in HCC cell lines and normal hepatic epithelial cell line was detected in vitro. Huh7 cell line with stable over⁃expression of Cx32 was further established, and the change in cell proliferation ability was measured by MTT assay, changes in migration and invasion capacities were detected by wound⁃healing assay and transwell assay, on this cell line. Finally, western blot and immunofluorescence (IF) were used to investigate the alterations of expression of epithelial⁃mesenchymal transition (EMT) markers. Results: Bioinformatics analyses showed that Cx32 mRNA and protein expression levels in HCC tissues were lower than those in normal liver tissues, and the mRNA expression level of Cx32 was negatively correlated with T stage, histological grade and clinical stage of HCC patients (all P<0.05). Results of in vitro experiments revealed Cx32 protein expression in different HCC cell lines was down⁃regulated compared to that in normal hepatic epithelial cell line LO2. Cx32 stably over⁃expressed (Cx32 OE) Huh7 cell line was successfully constructed by lentivirus infection and showed high expression of Cx32 protein in the cell line. Compared to the control group and (or) the negative control (NC) group, the Cx32 OE group exhibited decreased OD490 value, wound healing rate and invasive cell number (all P<0.05). Furthermore, an increase in the expression of epithelial marker E⁃cadherin, and a decrease in the expression of mesenchymal markers Snail and Vimentin, were observed in Cx32⁃OE Huh7 cell line. Conclusion: Cx32 is low expressed in HCC tissues and cells, while the proliferation, migration and invasion ability of Huh7 cells can be inhibited by over⁃expression of Cx32, of which the underlying mechanism may be related to the inhibition of EMT process. | JI Wen‑bin LV Zhen‑yu CHENG Qian‑qian ZHOU Xue‑li WANG Wei YANG Yan | 2023 | Journal of Hainan Medical University2023，29，2： | 0 |
| 18 | Targeting glioma stem cells via the Hedgehog signaling pathway显示文摘Cancer is one of the leading causes of death worldwide.Gliomas are among the most devastating tumor types,and current clinical therapies are unsatisfactory.Recent reports revealed the importance of glioma-propagating cells in the malignancy of gliomas.These cells,also referred to as glioma stem cells(GSCs),share similarities with neural stem cells(NSCs).The Hedgehog(Hh)signaling pathway controls tissue polarity,patterning maintenance,and maintenance of NSCs during embryonic development.Aberrant activation of the Hh pathway resulting from mutation and deregulation has recently been recognized to cause tumorigenesis in a wide variety of tissues,including gliomas and GSCs.In this review,we explore the role of the Hh signaling pathway in GSCs and its potential as a therapeutic strategy. | Yang Liu Xing Liu Ling‑Chao Chen Wen‑Zhong Du Yu‑Qiong Cui Xing‑Yin Piao Yong‑Li Li Chuan‑Lu Jiang | 2014 | Neuroimmunology and Neuroinflammation2014，1，1： | 0 |
| 19 | TRIM72‑mediated degradation of the short form of p62/SQSTM1 rheostatically controls selective autophagy in human cells显示文摘Dear Editor,Autophagy is an evolutionarily conserved catabolic process that involves the sequestration and transport of organelles,macromolecules,or invading microorganisms to lysosomes for degradation[1].Sequestosome 1(p62/SQSTM1)was the first protein shown to bind target-associated ubiquitin(Ub)and LC3 conjugated to the phagophore membrane,thus,acting as an important autophagy receptor for ubiquitinated targets[2]. | Cheng‑Cheng Wang Hong Peng Zi Wang Jiao Yang Rong‑Gui Hu Chuan‑Yin Li Wu‑Jun Geng | 2023 | Military Medical Research2023，10，4： | 0 |
| 20 | Two‑parameter dynamical scaling analysis of single‑phase natural circulation in a simple rectangular loop based on dilation transformation显示文摘Scaling analysis is widely used to design scaled-down experimental facilities through which the prototype phenomena can be effectively evaluated.As a new method,dynamic system scaling(DSS)must be verified as a rational and applicable method.A DSS method based on dilation transformation was evaluated using single-phase natural circulation in a simple rectangular loop.The scaled-down cases were constructed based on two parameters—length ratio and dilation number—and the corresponding transient processes were simulated using the Relap5 computational code.The results show that this DSS method can simulate the dynamic flow characteristics of scaled-down cases.The transient deviation of the temperature difference and mass flow rate of the scaled cases decrease with increases in the length ratio and dilation number.The distortion of the transient temperature difference is smaller than that of the mass flow;however,the overall deviation is within a reasonable range. | Jia‑Ning Xu Xiang‑Bin Li Yu‑Sheng Liu Shuai Yang De‑Chen Zhang Qiao Wu | 2022 | Nuclear Science and Techniques2022，33，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员