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| 1 | China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design显示文摘 | Rachel P Dreyer Xi Li Xue Du Nicholas S Downing Li Li Hai-Bo Zhang Fang Feng Wen-Chi Guan Xiao Xu Shu-Xia Li Zhen-Qiu Lin Frederick A Masoudi John A Spertus Harlan M Krumholz Li-Xin Jiang | 2016 | Chinese Medical Journal2016，，1： | 13 |
| 2 | 曹雪涛院士科研团队论文荣膺中国百篇最具影响国际学术论文--长链非编码RNA1nc-DC通过STAT3调控人DC的分化和功能显示文摘树突状细胞(DC)是免疫系统中重要的抗原提呈细胞,其成熟和功能状态决定着免疫应答的走向和强度。哺乳动物基因组能够转录产生大量的长链非编码RNA(long noncoding RNA,IncRNA),其在免疫系统中的功能还知之甚少。
曹雪涛院十科研团队王品副教授课题组采用了转录组芯片二代测序高通量筛选方法、RNA-pulldown、ChIP-seq等技术展开了对IncRNA在DC分化和功能中作用的研究,发现并鉴定了特异性高表达于DC的1ncRNA,命名为1nc-DC,其可通过抑制STAT3去磷酸化,从而促进DC分化和功能。该研究成果发表于Science杂志[2014,344(6181):310-313],并于2015年12月被评为“中国百篇最具影响国际学术论文”。 | wang p xue y han y lin l wu c xu s jiang z xu j liu q cao x | 2016 | 中国肿瘤生物治疗杂志2016，23，1： | 10 |
| 3 | Rho A signaling and blood pressure: The consequence of failing to “Tone it Down”显示文摘Uncontrolled high blood pressure is a major risk factor for heart attack, stroke, and kidney failure and contributes to an estimated 25% of deaths worldwide. Despite numerous treatment options, estimates project that reasonable blood pressure(BP) control is achieved in only about half of hypertensive patients. Improvements in the detection and management of hypertension will undoubtedly be accomplished through a better understanding of the complex etiology of this disease and a more comprehensive inventory of the genes and genetic variants that influence BP regulation. Recent studies(primarily in pre-clinical models) indicate that the small GTPase Rho A and its downstream target, Rho kinase, play an important role in regulating BP homeostasis. Herein, we summarize the underlying mechanisms and highlight signaling pathways and regulators that impart tight spatial-temporal control of Rho A activity. We also discuss known allelic variations in the Rho A pathway and consider how these polymorphisms may affect genetic risk for hypertension and its clinical manifestations. Finally, we summarize the current(albeit limited) clinical data on the efficacy of targeting the Rho A pathway in hypertensive patients. | Xue Bai Rachel Dee Kevin D Mangum Christopher P Mack Joan M Taylor | 2016 | World Journal of Hypertension2016，6，1： | 3 |
| 4 | A review of rapid prototyping technologies and systems显示文摘 | Xue Yan P Gu | 1996 | Computer-Aided Design1996，，4： | 2 |
| 5 | Immnopotentiation of bovine respiratory disease virus vaccines by interleukin-l and interleukin-2显示文摘 | Reddy D N Reddy P G Xue W | 1993 | Vet Immunol Immopathol1993，37，： | 2 |
| 6 | Evaluating land surface moisture conditions from the remotely sensed temperature/vegetation index measurements显示文摘 | Samuel N Goward Yongkang Xue Kevin P Czajkowski | 2001 | Remote Sensing of Environment2001，，2： | 2 |
| 7 | Effet of Maotai liguor in inducing metallothioneins and on hepatic stellate cells显示文摘 | Cheng ML Wu J Wang HQ Xue LM Tan YZ Liu P Li CX Huang NH Yao YM Ren LZ Ye L Li L Jia ML | 2001 | Shijie Huaren Xiaohua Zazhi2001，9，12： | 2 |
| 8 | Microstructural evolution in adiabatic shear localization in stainless steel显示文摘 | M.A. Meyers Y.B. Xu Q. Xue M.T. Pérez-Prado T.R. McNelley | 2003 | Acta Materialia2003，，5： | 2 |
| 9 | A review of rapid prototyping technologies and system 显示文摘 | Xue Yah P Gu | 1996 | Computer Aided Design1996，28，4： | 1 |
| 10 | GH6 characterization of a Neocallimastix patriciarum cellulase cDNA (celA) homologous to Trichoderma reesei cellobiohydrolase II 显示文摘 | DENMAN S XUE G P PATEL B | 1996 | Appl Environ Microbiol1996，62，6： | 1 |
| 11 | Dissolved organic matter (DOM) in recycled leachate of bioreactor landfill 显示文摘 | He P J Xue J F Shao L M | 2006 | Water Res2006，40，7： | 1 |
| 12 | Theoretical prediction of the springback of metal sheets after a double-curvature forming operation显示文摘 | Xue P Yu T X | 1999 | Journal of Material Processing Technology1999，8990，： | 1 |
| 13 | A new disease in rabbits显示文摘 | Liu S J Xue H P Pu B Q | 1984 | Anima Husb Vet Med1984，16，： | 1 |
| 14 | The number of neighbors needed for connectivity of wireless networks显示文摘 | XUE F KUMAR P | 2004 | Wireless Networks2004，10，： | 1 |
| 15 | Folate deficiency induces aneuploidy in human lymphocytes in vitro--evidence using cytokinesis-blocked cells and probes specific for chromosome 17 and 21显示文摘 | Wang X Thomas P Xue JL | 2004 | Mutat Res2004，551，12： | 1 |
| 16 | A1203 ceramics with well-oriented and hexagonally ordered pores: the forma- tion of microstructures and the control of properties显示文摘 | XUE W J HUANG Y XIE Zh P | 2012 | J Eur Ceram Soc2012，32，： | 1 |
| 17 | A memory retrieval-extinction procedure to prevent drug craving and relapse显示文摘 | Xue YX Luo YX Wu P | | 0，，： | 1 |
| 18 | Transcriptional activation of steroidogenic factor-I by hypomethylation of the 5'CpG island in endometriosis显示文摘 | Xue Q Lin Z Yin P | 2007 | Clin Endocrinol Metab2007，92，： | 1 |
| 19 | Super-hydrophilicproperties of TiO 2 -DLC nanocomposite films fabricated by the sim-ple electrochemical process显示文摘 | Wan S H Wang L P Xue Q J | 2011 | Applied Surface Science2011，257，10： | 1 |
| 20 | ERCC1 and BRCA1 mRNA expressions are associated with clinical outcome of non-small cell lung cancer treated with platinum-based chemotherapy 显示文摘 | Zhao L P Xue C Zhang J W | 2012 | Chin J Cancer2012，31，10： | 1 |
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