|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 血管周围脂肪组织中的Bmal1通过血管紧张素原转录调控管理静息期血压显示文摘血管周围脂肪组织(perivascular adipose tissue,PVAT)围绕血管,构成了在生理条件下保持血管张力所需的脉管系统的独特的功能整体层。然而,关于PVAT与血压调节之间的关系的资料很少,包括其对昼夜血压变化的潜在作用。 | Chang L Xiong W Zhao X Fan Y Guo Y Garcia-Barrio M Zhang J Jiang Z Lin JD Chen YE 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，2： | 23 |
| 2 | Systematic review of TCF2 anomalies in renal cysts and diabetes syndrome/maturity onset diabetes of the young type 5显示文摘在那里的目的是出版工作的少量系统地与肾的包囊和年轻类型的糖尿病症候群(RCAD )/maturity 发作糖尿病评估基因异例或病人的临床的特征 5 (MODY5 ) 。这评论的目的是系统地估计察觉率,基因并且异质接合的正染色体的主导的 TCF2 anomalies.Data 来源 MEDLINE 数据库的 phenotypic 含意被寻找选择从 1997 ~ 2008 用英语记录的文章。焦点是 monoallelic germline TCF2 基因变化 / 删除。 Biallelic inactivation ,多型性, DNA 修正( hypomethylation 和 hypermethylation ),与癌症风险联系的 loci ,和体的 TCF2 异例都是在寻找文学以后的 excluded.Study 选择, 50 篇文章是 TCF2 异例的察觉率是的 selected.Results 9.7%并且在 MODY (1.4%)之中更加变化了,肾的结构异例( RSA )(21.4%)和有 MODY (41.2%)亚群的 RSA 。变化惊人地位于 DNA 有约束力的域以内并且在 DNA 有约束力的域的 exons 之中变化了:exons 2 和 4 是最热的点,当变化在 exon 是偶发地分布式的时 3。一致显型是 RSA (89.6%) 和糖尿病 mellitus (DM )(45.0%) 。然而, RSA 和 DM 的同时发生是相对低的(27.5%) ,它妨碍基因测试和及时诊断的获得的最佳的表演。另外的机关参与为有 TCF2 异例的病人的早鉴定补足、必要。TCF2 点变化的显型的分析根据变化类型然而并非 utation location.Conclusion 处于 RSA,损害肾的功能(IRF ) 和 DM 的察觉率显示出重要差别以前没收到足够的注意的 TCF2 异例的这些珍贵特征不应该被忽视。 | CHEN Yi-zhi GAO Qing ZHAO Xue-zhi CHEN Ying-zhang Craig L Bennett XIONG Xi-shan MEI Chang-lin SHI Yong-quan CHEN Xiang-mei | 2010 | Chinese Medical Journal2010，，22： | 21 |
| 3 | Combined acoustic radiation force impulse, aminotransferase to platelet ratio index and Forns index assessment for hepatic fibrosis grading in hepatitis B显示文摘AIM: To investigate the combined diagnostic accuracy of acoustic radiation force impulse(ARFI), aspartate aminotransferase to platelet ratio index(APRI) and Forns index for a non-invasive assessment of liver fibrosis in patients with chronic hepatitis B(CHB). METHODS: In this prospective study, 206 patients had CHB with liver fibrosis stages F0-F4 classified by METAVIR and 40 were healthy volunteers were measured by ARFI, APRI and Forns index separately or combined as indicated. RESULTS: ARFI, APRI or Forns index demonstrated a significant correlation with the histological stage(all P < 0.001). According to the AUROC of ARFI and APRI for evaluating fibrotic stages more than F2, ARFI showed an enhanced diagnostic accuracy than APRI(P < 0.05). The combined measurement of ARFI and APRI exhibited better accuracy than ARFI alone when evaluating ≥ F2 fibrotic stage(Z = 2.77, P = 0.006). Combination of ARFI, APRI and Forns index did not obviously improve the diagnostic accuracy compared to the combination of ARFI and APRI(Z = 0.958, P = 0.338). CONCLUSION: ARFI + APRI showed enhanced diagnostic accuracy than ARFI or APRI alone for significant liver fibrosis and ARFI + APRI + Forns index shows the same effect with ARFI + APRI. | Chang-Feng Dong Jia Xiao Ling-Bo Shan Han-Ying Li Yong-Jia Xiong Gui-Lin Yang Jing Liu Si-Min Yao Sha-Xi Li Xiao-Hua Le Jing Yuan Bo-Ping Zhou George L Tipoe Ying-Xia Liu | 2016 | World Journal of Hepatology2016，8，14： | 18 |
| 4 | Characteristic-based operator-splitting finite element method for Navier-Stokes equations显示文摘A new finite element method, which is the characteristic-based operator-splitting (CBOS) algorithm, is developed to solve Navier-Stokes (N-S) equations. In each time step, the equations are split into the diffusive part and the convective part by adopting the operator-splitting algorithm. For the diffusive part, the temporal discretization is performed by the backward difference method which yields an implicit scheme and the spatial discretization is performed by the standard Galerkin method. The convective part can be discretized using the characteristic Galerkin method and solved explicitly. The driven square flow and backward-facing step flow are conducted to validate the model. It is shown that the numerical results agree well with the standard solutions or existing experimental data, and the present model has high accuracy and good stability. It provides a prospective research method for solving N-S equations. | WANG DaGuo WANG HaiJiao XIONG JuHua THAM L G | 2011 | Science China(Technological Sciences)2011，54，8： | 13 |
| 5 | Ultra fast microwave-assisted leaching for the recovery of copper and tellurium from copper anode slime显示文摘The decomposition of copper anode slime heated by microwave energy in a sulfuric acid medium was investigated. Leaching experiments were carried out in a multi-mode cavity with microwave assistance. The leaching process parameters were optimized using response surface methodology(RSM). Under the optimized conditions, the leaching efficiencies of copper and tellurium were 99.56% ± 0.16% and 98.68% ± 0.12%, respectively. Meanwhile, a conventional leaching experiment was performed in order to evaluate the influence of microwave radiation. The mechanism of microwave-assisted leaching of copper anode slime was also investigated. In the results, the microwave technology is demonstrated to have a great potential to improve the leaching efficiency and reduce the leaching time. The enhanced recoveries of copper and tellurium are believed to result from the presence of a temperature gradient due to the shallow microwave penetration depth and the superheating at the solid-liquid interface. | Zhi-yuan Ma Hong-ying Yang Song-tao Huang Yang Lü Liu Xiong | 2015 | International Journal of Minerals,Metallurgy and Materials2015，22，6： | 11 |
| 6 | Image formation of brain function in patients suffering from knee osteoarthritis treated with moxibustion显示文摘OBJECTIVES:Functional magnetic resonance imaging(fMRI) technology was used to study changes to the resting state blood flow in the brains of patients with knee osteoarthritis(KOA) before and after treatment with moxibustion at the acupoint of the left Dubi(ST 35) and to probe the cerebral mechanism underlying the effect of moxibustion.METHODS:The resting state brain function of 30 patients with left KOA was scanned with fMRI before and after treatment with moxibustion.The analytic methods of fractional amplitude of low frequency fluctuation(fALFF) and regional homogeneity(ReHo) were used to observe changes in resting state brain function.RESULTS:The fALFF values of the right cerebrum,extra-nucleus,left cerebellum,left cerebrum and white matter of patients after moxibustion treatment were higher than before treatment,and the fALFF values of the precentral gyrus,frontal lobe and occipital lobe were lower than before treatment(P<0.05,K≥85).The ReHo values of the thalamus,extra-nucleus and parietal lobe of patients were much higher than those before moxibustion treatment,and the ReHo values of the right cerebrum,left cerebrum and frontal lobe were lower than before treatment(P<0.05,K≥85).CONCLUSION:The influence of moxibustion on obvious changes in brain regions basically conforms to the way that pain and warmth is transmitted in the body,and the activation of sensitive systems in the body may be objective evidence of channel transmission.The regulation of brain function by moxibustion is not in a single brain region but rather in a network of many brain regions. | Hongwu Xie Fangming Xu Rixin Chen Tianyou Luo Mingren Chen Weidong Fang Fajin Lü Fei Wu Yune Song Jun Xiong | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 7 |
| 7 | Hematopoietic stem cell-derived adipocytes and fibroblasts in the tumor microenvironment显示文摘The tumor microenvironment(TME) is complex and constantly evolving. This is due, in part, to the crosstalk between tumor cells and the multiple cell types that comprise the TME, which results in a heterogeneous population of tumor cells and TME cells. This review will focus on two stromal cell types, the cancerassociated adipocyte(CAA) and the cancer-associated fibroblast(CAF). In the clinic, the presence of CAAs and CAFs in the TME translates to poor prognosis in multiple tumor types. CAAs and CAFs have an activated phenotype and produce growth factors, inflammatory factors, cytokines, chemokines, extracellular matrix components, and proteases in an accelerated and aberrant fashion. Through this activated state, CAAs and CAFs remodel the TME, thereby driving all aspects of tumor progression, including tumor growth and survival, chemoresistance, tumor vascularization, tumor invasion, and tumor cell metastasis. Similarities in the tumorpromoting functions of CAAs and CAFs suggest that a multipronged therapeutic approach may be necessary to achieve maximal impact on disease. While CAAs and CAFs are thought to arise from tissues adjacent to the tumor, multiple alternative origins for CAAs and CAFs have recently been identified. Recent studies from our lab and others suggest that the hematopoietic stem cell, through the myeloid lineage, may serve as a progenitor for CAAs and CAFs. We hypothesize that the multiple origins of CAAs and CAFs may contribute to the heterogeneity seen in the TME. Thus, a better understanding of the origin of CAAs and CAFs, how this origin impacts their functions in the TME, and thetemporal participation of uniquely originating TME cells may lead to novel or improved anti-tumor therapeutics. | Ying Xiong Lindsay T Mc Donald Dayvia L Russell Ryan R Kelly Katie R Wilson Meenal Mehrotra Adam C Soloff Amanda C LaRue | 2015 | World Journal of Stem Cells2015，7，2： | 6 |
| 8 | Determination of critical slip surface of fractured rock slopes based on fracture orientation data显示文摘The critical slip surface of a fractured rock slope tends to extend along the fractures.Thus,fracture orientation plays a critical role in determining the critical slip surface.Based on fracture orientation data,this paper examines the critical slip surfaces of fractured rock slopes.Given that the surface of a fractured rock slope extends along the fracture surfaces,or the wedges,with each composed of two arbitrary fractures,the critical slip surface is determined via stochastic dynamics.In addition,a fracture frequency method is proposed as a means of analyzing the critical slip surface.According to this method,the critical slip surface slips in whichever direction has the lowest fracture frequency.Based on the stochastic dynamics method and the fracture frequency method,the critical slip surface of the slope is finally determined,that is,the critical slip surface takes the form of a plane passing the slope toe with a dip of 120° and a dip angle of 45°. | ZHANG Wen CHEN JianPing ZHANG Wu L Yan MA YuFei XIONG Hui | 2013 | Science China(Technological Sciences)2013，56，5： | 5 |
| 9 | Sequential slip transfer of mixed-character dislocations across Σ3 coherent twin boundary in FCC metals: a concurrent atomistic-continuum study显示文摘Sequential slip transfer across grain boundaries(GB)has an important role in size-dependent propagation of plastic deformation in polycrystalline metals.For example,the Hall–Petch effect,which states that a smaller average grain size results in a higher yield stress,can be rationalised in terms of dislocation pile-ups against GBs.In spite of extensive studies in modelling individual phases and grains using atomistic simulations,well-accepted criteria of slip transfer across GBs are still lacking,as well as models of predicting irreversible GB structure evolution.Slip transfer is inherently multiscale since both the atomic structure of the boundary and the long-range fields of the dislocation pile-up come into play.In this work,concurrent atomistic-continuum simulations are performed to study sequential slip transfer of a series of curved dislocations from a given pile-up onΣ3 coherent twin boundary(CTB)in Cu and Al,with dominant leading screw character at the site of interaction.A Frank-Read source is employed to nucleate dislocations continuously.It is found that subject to a shear stress of 1.2 GPa,screw dislocations transfer into the twinned grain in Cu,but glide on the twin boundary plane in Al.Moreover,four dislocation/CTB interaction modes are identified in Al,which are affected by(1)applied shear stress,(2)dislocation line length,and(3)dislocation line curvature.Our results elucidate the discrepancies between atomistic simulations and experimental observations of dislocation-GB reactions and highlight the importance of directly modeling sequential dislocation slip transfer reactions using fully 3D models. | Shuozhi Xu Liming Xiong Youping Chen David L McDowell | 2016 | npj Computational Materials2016，，1： | 4 |
| 10 | Identifying topologies and system parameters of uncertaintime-varying delayed complex networks显示文摘Node dynamics and network topologies play vital roles in determining the network features and network dynamical behaviors.Thus it is of great theoretical significance and practical value to recover the topology structures and system parameters of uncertain complex networks with available information. This paper presents an adaptive anticipatory synchronization-based approach to identify the unknown system parameters and network topological structures of uncertain time-varying delayed complex networks in the presence of noise. Moreover, during the identification process, our proposed scheme guarantees anticipatory synchronization between the uncertain drive and constructed auxiliary response network simultaneously. Particularly, our method can be extended to several special cases. Furthermore, numerical simulations are provided to verify the effectiveness and applicability of our method for reconstructing network topologies and node parameters. We hope our method can provide basic insight into future research on addressing reconstruction issues of uncertain realistic and large-scale complex networks. | WANG Xiong GU HaiBo WANG QianYao Lü JinHu | 2019 | Science China(Technological Sciences)2019，62，1： | 4 |
| 11 | Study of Digital Management System of Milking Process on Large-Sized Dairy Farm显示文摘This study was to supply the systemic and full milking process data to support the implementation of both dairy herd improvement(DHI)and digital feeding of dairy cattle.This study designed the relational structured database and developed a set of digital management information system on milking process of intensive dairy farm using Visual Basic 6.0,Access databases,and Crystal report combining the milking characteristics of a grown cow,such as quality and sanitation testing indexes of raw milk.The system supplies a series of convenient,intelligent input interfaces of crude datum,and can count,analyze,and graphically show milking datum based on different types and different parities of cows or herds in a specific duration,and can dynamically produce some important derived data,such as days of grown cow, daily average of milk production of grown cow,days of cow milk production,and daily average of milking cow production; and can carry out all-pervasive data mining.With the help of system analysis and software design techniques,it is possible to realize precision farming for a dairy cattle herd based on whole digital management of milking process and realtime prediction on nutrient requirements and ration of dairy cattle,as well as dairy herd improvement. | XIONG Ben-hai LUO Qing-yao Lǔ Jian-qiang YANG Liang | 2008 | Agricultural Sciences in China2008，7，8： | 3 |
| 12 | Role of oxygen and ammonium ions in silver leaching with thiosulfate–ammonia–cupric ions显示文摘The dissolution of silver with thiosulfate and copper ions was studied in a batch-stirred reactor at 25 °C in the absence and presence of various ammonium ions and oxygen concentrations in the aqueous solution. Leaching silver with 4 mg L-1oxygen in the aqueous solution requires high concentration of ammonium and thiosulfate ions. High silver dissolution is achieved at pH of high cupric tetraamine concentration, around pH 9.8, but a high degradation of thiosulfate ions is resulted from their oxidation by the presence of oxygen. When the oxygen concentration is below 1 mg L-1, dissolved silver thiosulfate species are fairly stable and the degradation of thiosulfate ions in the aqueous solution is low. Under these conditions,high silver dissolution is attained using low thiosulfate concentration. At the oxygen concentration of 4 mg L-1,dissolved silver thiosulfate species precipitate out of the aqueous solution significantly affecting silver dissolution.Precipitation of dissolved silver thiosulfate species occurs because of oxidation of the thiosulfate bonding to the silver. | Valentin Ibarra-Galvan Alejandro López-Valdivieso Xiong Tong Yi-Qi Cui | 2014 | Rare Metals2014，33，2： | 3 |
| 13 | Isoflurane tolerance against focal cerebral ischemia is attenuated by adenosine Al receptor antagonists显示文摘 | Liu Y Xiong L Chen S | 2006 | Can J Anaesth2006，53，2： | 1 |
| 14 | Transient liquid - phase diffusion bonding of two- dimensional carbon- carbon composites to niobium alloy显示文摘 | J - L LI J - T XIONG F - S ZHANG | 2007 | Materials Science and Engineering A2007，，484： | 1 |
| 15 | Ultra-high g deceleration-time measurement for the penetration into steel target显示文摘 | Zhang W D Chen L J Xiong Jijun | 2007 | International Journal of Impact Engineering2007，34，3： | 1 |
| 16 | Alkaline syenites in eastern Cathaysia (South China): Link to Permian-Triassic transtension显示文摘 | Wang Q Li J W Jian P Zhao Z H Xiong X L Bao Z W Xu J F Li C F Ma J L | 2005 | Emth Planet Sci Lett2005，230，34： | 1 |
| 17 | CT and MRI characteristics of ossification of the ligamentum flava in the thoracic spine显示文摘 | Xiong L Zeng QY Jinkins JR | 2001 | Eur Radiol2001，11，9： | 1 |
| 18 | Aeolian origin of the redearth in southeast China显示文摘 | Xiong S F Sun D H Ding Z L | 2002 | Journal of Quaternary Science2002，17，： | 1 |
| 19 | Mural granulosa cellgene expression associated with oocye developmental compe-tence显示文摘 | Jiang J Y Xiong H L Cao M J | 2010 | Ovarian Res2010，3，1： | 1 |
| 20 | Patterns of cytosine methylation in an elite rice hybrid and its parental lines, detected by a methylation - sensitive amplification polymorphism technique 显示文摘 | Xiong L Z Xu C G Saghai Maroof M A Zhang Q F | 1999 | Molecular and General Genetics1999，261，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员