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| 1 | The role of radiotherapy in localised and locally advanced prostate cancer显示文摘For a patient suffering from non-metastatic prostate cancer,the individualized recommendation of radiotherapy has to be the fruit of a multidisciplinary approach in the context of a Tumor Board,to be explained carefully to the patient to obtain his informed consent.External beam radiotherapy is now delivered by intensity modulated radiotherapy,considered as the gold standard.From a radiotherapy perspective,low-risk localized prostate cancer is treated by image guided intensity modulated radiotherapy,or brachytherapy if patients meet the required eligibility criteria.Intermediate-risk patients may benefit from intensity modulated radiotherapy combined with 4e6 months of androgen deprivation therapy;intensity modulated radiotherapy alone or combined with brachytherapy can be offered to patients unsuitable for androgen deprivation therapy due to co-morbidities or unwilling to accept it to preserve their sexual health.High-risk prostate cancer,i.e.high-risk localized and locally advanced prostate cancer,requires intensity modulated radiotherapy with long-term(≥2 years)androgen deprivation therapy with luteinizing hormone releasing hormone agonists.Post-operative irradiation,either immediate or early deferred,is proposed to patients classified as pT3pN0,based on surgical margins,prostate-specific antigen values and quality of life.Whatever the techniques and their degree of sophistication,quality assurance plays a major role in the management of radiotherapy,requiring the involvement of physicians,physicists,dosimetrists,radiation technologists and computer scientists.The patients must be informed about the potential morbidity of radiotherapy and androgen deprivation therapy and followed regularly during and after treatment for tertiary prevention and evaluation.A close cooperation is needed with general practitioners and specialists to prevent and mitigate side effects and maintain quality of life. | Michel Bolla Ann Henry Malcom Mason Thomas Wiegel | 2019 | Asian Journal of Urology2019，6，2： | 5 |
| 2 | 支持完整性决策的数据管理显示文摘大多数管道的运营、维护和其它设备管理部门,采用一系列各自独立的数据资源和应用程序来管理管道的完整性、维修和安全。将各个独立的数据整合成一个单一的、相互关联的数据管理系统可以提供很多重要的好处。然而,在给定管道早期投资的情况下,评价用于建立一个包含功能强大的数据采集程序在内的新系统的成本是非常困难的。采用静态的和独立的维护性数据的专用风险管理软件被作为一种快捷的、低成本的替代选择,以此来满足规章制度所规定的必须遵从的行业要求。通过开发传统数据等方法,以最小的启动成本来实现阶段性的完整性数据管理。 | John Beets Ed Wiegele Stuart Clouston | 2005 | 油气储运2005，24，B12： | 2 |
| 3 | Polar interactions of chondroitin sulfate: surface free energy and molecular dynamics simulations 显示文摘 | WIEGEL D KAUFMANN J ARNOLD K | 1999 | Colloids and Surfaces B: Biointerfaces1999，13，3： | 1 |
| 4 | Phase III post- operative adjuvant radiotherapy after radical prostatectomycom- pared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-speeific antigen: ARO 96-02/AUOAP 09/95显示文摘 | WIEGEL T BOTTKE D STEINER U | 2009 | J Clin Oncol2009，2027，18： | 1 |
| 5 | Purification and characterization of a thermostable β- xylosidase from Thmoanarerobacter ethanolicus显示文摘 | Shao W Wiegel J | 1992 | J Bacteriol1992，174，： | 1 |
| 6 | Fiber crossing in human brain depicted with diffusion tensor MR imaging显示文摘 | Wiegell MR Larsson HBW Van Wedeen J | 2000 | Radiology2000，217，3： | 1 |
| 7 | Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate显示文摘 | Wiegell SR Wulf HC | 2006 | J Am Acad Dermatol2006，54，4： | 1 |
| 8 | Pharmaceuticals in the river Elbe and its tributaries显示文摘 | Wiegel S Aulinger A Brockmeyer R | 2004 | Chemosphere2004，57，2： | 1 |
| 9 | Fiber crossing in human brain depicted with diffusion tensor MR inuging显示文摘 | Larsson HBW Wedeen VJ | 2000 | Radiology2000，217，： | 1 |
| 10 | A presentation of cnoidal wave theory for practical application 显示文摘 | WIEGEL R | 1960 | Journal of Fluid Mechanics1960，7，2： | 1 |
| 11 | Bladder cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up 显示文摘 | Bellmunt J Orsola A Wiegel T | 2011 | Ann Oncal2011，22，6： | 1 |
| 12 | Influence of incubation temperature on the microbial reductive dechlorination of 2,3,4,6-tetrachlorobiphenyl in two freshwater sediments显示文摘 | Wu Q Bedard D Wiegel J | | 0，，： | 1 |
| 13 | Water waves generated by landslides in reservoirs 显示文摘 | Robert L Wiegel Edward K Noda Dennis M Gee | 1970 | Journal of the Waterways Harbors and Coastal Engineering Division1970，96，2： | 1 |
| 14 | Intraoperative wake-up test and postoperative emergence in patients undergoing spinal surgery: a comparison of intravenous and inhaled anesthetic techniques using shortacting anesthetics 显示文摘 | Grottke O Dietrich P J Wiegels S | 2004 | Anesth Analg2004，99，5： | 1 |
| 15 | High angular resolution diffusion imaging reveals intravoxel white matter fiber heterogeneity显示文摘 | TUCH D S REESE T G WIEGELL M R | 2002 | Magnetic Resonance in Medicine2002，48，4： | 1 |
| 16 | Application of a multiple-trait herd cluster model for genetic evaluation of dairy sires from seventeen countries显示文摘 | Zwald N R Wiegel K A Fikse W F | 2003 | J Dairy Sci2003，86，： | 1 |
| 17 | Diffilsiun MRI of complex neural architecture 显示文摘 | Tuch DS Reese TG Wiegell MR | 2003 | Neuron2003，40，5： | 1 |
| 18 | Intraoperative wake-up test and postoperative pmergence in patients undergoing spinal surgery : A comparison of intravenous and inhaled anesthetic tech- niques using short-acting anesthetics显示文摘 | Grottke O Dietrich PJ Wiegels S | 2004 | Anesth Analg2004，99，： | 1 |
| 19 | Microbial reductive dehalogenation of polychlorinated biphenyls 显示文摘 | Wiegel J Wu Q Z | 2000 | FEMS Microbiology Ecology2000，32，： | 1 |
| 20 | Bladder cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and fol- low-up显示文摘 | Bellmunt J Orsola A Wiegel T | 2011 | Ann Onco12011，22，6： | 1 |
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