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| 1 | Shear-induced crystallization in novel long chain branched polypropylenes by in situ Rheo-SAXS and Rheo-WAXD显示文摘 | AGARWAL P K SOMANI R H WENG W | 2003 | Macromolecules2003，36，： | 1 |
| 2 | Comparative studies on the hypolipidemic and growth suppressive effects of oolong, black, pu-erh, and green tea leaves in rats显示文摘 | Kuo K L Weng M S Chiang C T | 2005 | Journal of Agricultural and Food Chemistry2005，53，2： | 1 |
| 3 | Size- and density-controlled synthesis of TiO2 nanodots on a substrate by phase-separation-induced self-assembly 显示文摘 | LUO M CHENG K WENG W J | 2009 | Nanotechnology2009，20，21： | 1 |
| 4 | Video object tracking using adaptive Kalman filter显示文摘 | WENG S K KUO C M TU S K | 2006 | Journal of Visual Communication and Image Representation2006，17，6： | 1 |
| 5 | Channel coordination and quantity discount显示文摘 | Weng Z K | 1995 | Management Science1995，41，9： | 1 |
| 6 | Immobilizationof RGD peptide on HA coating through a chemical bondingapproach显示文摘 | YANG C L CHENG K WENG W J | 2009 | Journal of Materials Science:Materials in Medi-cine2009，20，11： | 1 |
| 7 | High-strength reinforced concrete deep and short beams:shear design equations in North America and UK practice显示文摘 | Tan K H Dong F K Weng L W | 1998 | ACI Structural Journal1998，95，3： | 1 |
| 8 | Wavelets period doubling and timefrequency localization with applleatlon to organization of con vection over the tropical western Pacific显示文摘 | Hengyi Weng K M Lau | 1994 | J Atmos Sci1994，51，17： | 1 |
| 9 | General models for the supplier's all-unit quantity discount policy 显示文摘 | Weng Z K Wong R T | 1993 | Naval Research Logistics (S0894-069X)1993，40，6： | 1 |
| 10 | Dynamic mag- netic forces in superconducting ceramic显示文摘 | Moon F C Weng K C Chang P Z | 1989 | J Appl Phys1989，66，3： | 1 |
| 11 | The C9orf72 GGGGCC repeat is translated into aggrega- ting dipeptide-repeat proteins in FTLD/ALS显示文摘 | MORI K WENG S-M ARZBERGER T | 2013 | Sci- ence2013，339，6125： | 1 |
| 12 | Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes显示文摘BACKGROUND Cigarette smoking(CS)is the most common method of consuming tobacco.Deleterious effects on bone integrity,increased incidence of fractures,and delayed fracture healing are all associated with CS.Over 150 of the 6500 molecular species contained in cigarette smoke and identified as toxic compounds are inhaled by CS and,via the bloodstream,reach the skeletal system.New technologies designed to develop a reduced-risk alternative for smokers are based on electronic nicotine delivery systems,such as e-cigarettes and tobacco heating systems(THS).THS are designed to heat tobacco instead of burning it,thereby reducing the levels of harmful toxic compounds released.AIM To examine the effects of THS on osteoprogenitor cell viability and function compared to conventional CS.METHODS Human immortalized mesenchymal stem cells(n=3)and primary human preosteoblasts isolated from cancellous bone samples from BG Unfall Klinik Tübingen(n=5)were osteogenically differentiated in vitro with aqueous extracts generated from either the THS 2.4“IQOS”or conventional“Marlboro”cigarettes for up to 21 d.Cell viability was analyzed using resazurin conversion assay(mitochondrial activity)and calcein-AM staining(esterase activity).Osteogenic differentiation and bone cell function were evaluated using alkaline phosphatase(AP)activity,while matrix formation was analyzed through alizarin red staining.Primary cilia structure was examined by acetylatedα-tubulin immunofluorescent staining.Free radical production was evaluated with 2’,7’-dichlorofluoresceindiacetate assay.RESULTS Our data clearly show that THS is significantly less toxic to bone cells than CS when analyzed by mitochondrial and esterase activity(P<0.001).No significant differences in cytotoxicity between the diverse flavors of THS were observed.Harmful effects from THS on bone cell function were observed only at very high,non-physiological concentrations.In contrast,extracts from conventional cigarettes significantly reduced the AP activity(by two-fold)and matrix mineralization(four-fold)at low concentrations.Additionally,morphologic analysis of primary cilia revealed no significant changes in the length of the organelle involved in osteogenesis of osteoprogenitor cells,nor in the number of ciliated cells following THS treatment.Assessment of free radical production demonstrated that THS induced significantly less oxidative stress than conventional CS in osteoprogenitor cells.CONCLUSIONTHS was significantly less harmful to osteoprogenitor cells during osteogenesisthan conventional CS. Additional studies are required to confirm whether THS isa better alternative for smokers to improve delays in bone healing followingfracture. | Romina H Aspera-Werz Sabrina Ehnert Monja Müller Sheng Zhu Tao Chen Weidong Weng Johann Jacoby Andreas K Nussler | 2020 | World Journal of Stem Cells2020，12，8： | 1 |
| 13 | Microstructure and mechanical properties of bulk Mg-Zn-Ca amorphous alloys and amorphous matrix composites显示文摘 | LI Q F WENG H R SUO Z Y REN Y L YUAN X G QIU K Q | 2008 | Mater Sci Eng A2008，487，： | 1 |
| 14 | Size-dependent ultraviolet luminescence and low-field electron emission of TiO2 nanodots formed by phase-separation-induced self-assembly 显示文摘 | LUO M CHENG K WENG W J | 2009 | J Phys D Appl Phys2009，42，10： | 1 |
| 15 | Levels and health risks of carbonyl compounds in selected public places in Hangzhou, China显示文摘 | Weng M L Zhu L Z Yang K | 2009 | J Hazard Mater2009，164，23： | 1 |
| 16 | Comparative studies on the hypolipidemic and growth suppressive effects of oolong,black,pu-erh,and green tea leaves in rats显示文摘 | KUO K L WENG M S CHIANG C T | 2005 | J Agric Food Chem2005，53，2： | 1 |
| 17 | OTS-modifiedHA and its toughening effect on PLLA/HA porous composite显示文摘 | YANG C L CHENG K WENG W J | 2009 | Journal of Materials Science:Materials in Medicine2009，20，3： | 1 |
| 18 | Channel coordination and quantity discounts显示文摘 | WENG K | 1995 | Management Science1995，41，9： | 1 |
| 19 | Pricing and ordering strategies in manufacturing and distribution alliances显示文摘 | Weng Z K | 1997 | IIE Transactions1997，29，： | 1 |
| 20 | A Risk Free Perishable Item Returns Policy 显示文摘 | Webster S Weng Z K | 2000 | Manufacturing & Service Operations Management2000，2，1： | 1 |
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