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| 1 | Response to endoscopic therapy for biliary anastomotic strictures in deceased versus living donor liver transplantation显示文摘BACKGROUND:Endoscopic therapy has been successful in the management of biliary complications after both deceased donor liver transplantation(DDLT) and living donor liver transplantation(LDLT).LDLT is thought to be associated with higher rates of biliary complications,but there are few studies comparing the success of endoscopic management of anastomotic strictures between the two groups.This study aims to compare our experience in the endoscopic management of anastomotic strictures in DDLT versus LDLT.METHODS:This is a retrospective database review of all liver transplant patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) after liver transplantation.The frequency of anastomotic stricture and the time to develop and to resolve anastomotic stricture were compared between DDLT and LDLT.The response of anastomotic stricture to endoscopic therapy was also analyzed.RESULTS:A total of 362 patients underwent liver transplantation between 2003 and 2011,with 125 requiring ERCP to manage biliary complications.Thirty-three(9.9%) cases of DDLT and 8(27.6%) of LDLT(P=0.01) were found to have anastomotic stricture.When comparing DDLT and LDLT,there was no difference in the mean time to the development of anastomotic strictures(98±17 vs 172±65 days,P=0.11),likelihood of response to ERCP [22(66.7%) vs 6(75.0%),P=0.69],mean time to the resolution of anastomotic strictures(268±77 vs 125±37 days,P=0.34),and the number of ERCPs required to achieve resolution(3.9±0.4 vs 4.7±0.9,P=0.38).CONCLUSIONS:Endoscopic therapy is effective in the majority of biliary complications relating to liver transplantation.Anastomotic strictures occur more frequently in LDLT compared with DDLT,with equivalent endoscopic treatment response and outcomes for both groups. | Calvin HY Chan Fergal Donnellan Michael F Byrne Alan Coss Mazhar Haque Holly Wiesenger Charles H Scudamore Urs P Steinbrecher Alan A Weiss Eric M Yoshida | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 7 |
| 2 | 富含组织细胞型横纹肌母细胞肿瘤:一种组织学独特的横纹肌母细胞肿瘤显示文摘许多软组织肿瘤不能简单地划分为“良性”或“恶性”。WHO软组织和骨肿瘤分类将几种类型的软组织肿瘤(如脂肪细胞肿瘤中的非典型脂肪瘤性肿瘤和内皮细胞肿瘤中的血管内皮瘤)确定为中间型(交界型)。一些软组织肿瘤(如韧带样型纤维瘤病和含铁血黄素沉着性纤维脂肪瘤性肿瘤)被认为是中度恶性肿瘤,这可能是因为它们具有局部侵袭性生长的能力,也可能因为它们(如血管瘤样纤维组织细胞瘤和骨化性纤维黏液样肿瘤)具有较低但无法预测的远处转移风险。血管球肿瘤和PEComa等肿瘤的分类系统不仅可以预测临床良、恶性肿瘤具有合理的敏感性和特异性,而且还可以将这些肿瘤的少部分划分为恶性潜能不确定型。有选择的软组织肿瘤(如胃肠道间质肿瘤和孤立性纤维性肿瘤),应从风险评估的角度来看待,而非良、恶性。显示骨骼肌分化的肿瘤传统上一分为二为良性横纹肌瘤或完全恶性横纹肌肉瘤(RMS)。 | Martinez A P Fritchie K J Weiss S W 张仁亚 | 2019 | 临床与实验病理学杂志2019，35，11： | 3 |
| 3 | Immunohistochemical analysis of the Wnt/β-catenin signaling pathway in pancreatic neuroendocrine neoplasms显示文摘AIM: To investigate the role of the Wnt/β-catenin pathway in pancreatic neuroendocrine neoplasms(PanN ENs). METHODS: Tissue microarrays containing 88 PanN ENs were immunohistochemically labeled with antibodies to β-catenin, E-cadherin, adenomatous polyposis coli(APC), chromogranin and synaptophysin. One case had only metastatic tumors resected, whereas others(n = 87) received pancreatectomy with or without partial hepatectomy. Pathology slides, demographic, clinicopathologic, and follow up data were reviewed. Patients' demographics, clinicopathologic features, and immunohistochemical results from 87 primary tumors were compared between patients with low stage(stage Ⅰ/Ⅱ) and high stage(stage Ⅲ/Ⅳ) tumors. In addition, correlation of immunohistochemical results from primary tumors with disease-specific survival(DSS) was evaluated. RESULTS: Strong membranous β-catenin staining in the primary tumor was observed in all 13 stage Ⅲ/Ⅳ Pan NENs as compared to 47%(35/74) of stage Ⅰ/Ⅱtumors(P < 0.01). However, the strong membranous β-catenin staining was unassociated with tumor grade or DSS. Decreased membranous β-catenin staining was associated with decreased membranous E-cadherin labeling. Nuclear β-catenin staining was seen in 15%(2/13) of stage Ⅲ/Ⅳ Pan NENs as compared to 0%(0/74) of stage Ⅰ/Ⅱ tumors(P = 0.02). The case with metastasectomy only also showed nuclear β-catenin staining. Two of the three cases with nuclear β-catenin staining were familial adenomatous polyposis(FAP) patients. Lack of APC expression was seen in 70%(57/81) of the cases, including the 3 cases with nuclear β-catenin staining. Expression of E-cadherin and APC in primary tumor was not correlated with tumor grade, tumor stage, or disease specific survival. CONCLUSION: The Wnt/β-catenin pathway was altered in some PanN ENs, but did not Impact DSS. PanN ENs in FAP patients demonstrated nuclear β-catenin accumulation and loss of APC. | Vivian Weiss Julie Dueber Jesse P Wright Justin Cates Frank Revetta Alexander A Parikh Nipun B Merchant Chanjuan Shi | 2016 | World Journal of Gastrointestinal Oncology2016，8，8： | 3 |
| 4 | Electromagnetic induction in a fully 3-D anisotropic earth 显示文摘 | WEISS C J NEWMAN G A | 2002 | Geophysics2002，67，4： | 1 |
| 5 | The coexistence of multiple distribution systems for financial services: The case of property-liability insurance显示文摘 | Berger Allen N Cummins J David Weiss Mary A | 1997 | Journal of Business1997，10，： | 1 |
| 6 | Heteronuclear 2D NMR studies of an engineered insulin monomer:assignment and characterization of the receptor-bingding surface by selective 2H and 13C labeling with application to protein design显示文摘 | Hua Q X Lynch C S | 1991 | Biochemistry1991，30，： | 1 |
| 7 | Assessing Residual Stress Development and Stress Relaxation in Restrained Concrete Ring Specimens显示文摘 | Hossain A B Weiss J | 2004 | Cement & Concrete Composite2004，26，： | 1 |
| 8 | Virulence factors of Bordetella pertussis显示文摘 | Weiss A A Hewlett E L | 1986 | Annu Rev Microbiol1986，40，： | 1 |
| 9 | Preparation of conductive polypyrrole/polyurethane compositefoams by in situ polymerization of pyrrole显示文摘 | Wang Y B sotzing G A Weiss R A | 2008 | Chem Mater2008，20，7： | 1 |
| 10 | Toxoplasma gondii : from animals to humans显示文摘 | Tenter A M Heckeroth A R Weiss L M | 2000 | Int J Parasitol2000，30，1213： | 1 |
| 11 | Expression of the adhesion molecules ICAM-1, VCAM-1, and E-selectin and their ligands VLA-4 and LFA-1 in chronic venous leg ulcers 显示文摘 | Weyl A Vanscheidt W Weiss JM | 1996 | J Am Acad Dermatol1996，34，3： | 1 |
| 12 | Preconditioning Applied to Variable and Const Density Flows显示文摘 | Weiss J M Simth W A | 1995 | AIAA1995，33，11： | 1 |
| 13 | Preparation and mechanical properties of ultrafine grained metals显示文摘 | Gunther B Baal man A Weiss H | 1990 | Journal of materials research1990，5，： | 1 |
| 14 | Direction finding using spatial smoothing with interpolated arrays 显示文摘 | FRIEDLANDER B WEISS A J | 1993 | IEEE Transaction on Signal Processing1993，41，4： | 1 |
| 15 | Investment in technological innovations:An option pricing approach显示文摘 | Grenadier S R Weiss A M | 1997 | Journal of Financial Economics1997，44，3： | 1 |
| 16 | Eigenstructure methods for direction finding with sensor gain and phase uncertainties 显示文摘 | Weiss A J Friedlander B | 1990 | Circutis Systems Signal Process1990，9，3： | 1 |
| 17 | The Stability of the AR(1) Process with an AR(I) Coefficient 显示文摘 | Weiss A A | 1985 | Journal of Time Series Analysis1985，6，3： | 1 |
| 18 | Credit rationing in the market with imperfect information 显示文摘 | STIGLITZ J WEISS A | 1981 | American Economic Review1981，73，3： | 1 |
| 19 | Epitopes of the CD4 antigen and HIV infection 显示文摘 | SATI'ENTAU Q J DALGLE1SH A G WEISS R A | 1986 | Science1986，234，4780： | 1 |
| 20 | What is metabolic syndrome, and why are children getting it? 显示文摘 | Weiss R Bremer A A Lustig R H | 2013 | Ann N Y Acad Sci2013，1281，： | 1 |
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