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| 1 | Ciliated hepatic foregut cyst:an increasingly diagnosed condition显示文摘BACKGROUND:Ciliated foregut cysts of the liver are rare, with only 96 cases diagnosed since the first description in 1857.They are being increasingly diagnosed recently;the majority of the cases have been reported in the last 15 years. Although they bear a close resemblance to the simple cyst of the liver which has essentially a benign course,ciliated hepatic foregut cysts(CHFCs)can progress to malignancy with devastating consequences.It is imperative that this group of conditions be diagnosed and treated adequately. DATA SOURCES:This review includes discussion of the data from all the 96 reported cases from English and non-English literature.Analysis of the incidence rates, embryogenesis,growth,clinical features,risk of malignancy and the prognosis are highlighted systematically.The roles of various diagnostic modalities including ultrasound, CT,MRI,fine needle aspiration cytology(FNAC), immunohistochemistry and surgery are further discussed. RESULTS:The mean age of patients with CHFC was 48± 12 years.The male/female ratio was 1.1∶1.The majority of patients with CHFC(62%)were asymptomatic,and the common mode of presentation was right upper abdominal pain.The cysts occurred in the left lobe in 51 patients, with sole location in segmentⅣin 44,and in the right lobe in 26.The average size of the cysts was 3.6±2.12 cm. The majority of the cysts were unilocular,and only 7 cases were multilocular.Cyst contents were described as viscous or mucinous in 73 patients,whereas bilious fluid was noted in 3.Large cysts having squamous carcinoma were cited in 3 patients,and 2 had extensive squamous metaplasia without malignancy.Others had benign histopathology. CONCLUSIONS:Clinicians have become increasingly aware of CHFC.Imaging alone is not diagnostic per se, but when considered in the context of the global picture does provide important clues to the diagnosis.FNAC is diagnostic by the presence of the ciliated columnar aspirate but lacks sensitivity.Infantile presentation is usually accompanied by biliary communication and mandates a different surgical approach.The demonstration of malignant transformation in 3 cases and its fatal course emphasizes the need for surgical resection in all cases once the diagnosis is made. | Sharad Sharma Amanda G.Dean Ayumi Corn Vivek Kohli Harlan I Wright Anthony Sebastian Nicolas Jabbour | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，6： | 2 |
| 2 | Herbal medicines as diuretics:A review of the scientific evidence显示文摘 | Wright C I Van-Buren L Kroner C I | 2007 | Journal of Ethnopharmacology2007，114，1： | 1 |
| 3 | Synthesis and DNA binding of spiroeyelic model compounds related to the neocarzinostatin chromophore 显示文摘 | Xi Z Jones G B Qabaja G Wright J Johnson F Goldberg I H | 1999 | Org Lett1999，1，9： | 1 |
| 4 | Differential scanning calorimetric studies of muscle and its constituent proteins 显示文摘 | Wright D J Leach I B Wilding P | 1977 | Journal of the Science of Food and Agriculture1977，28，： | 1 |
| 5 | Fundamental trade-offs generating the worldwide leaf economics spectrum 显示文摘 | Shipley B Lechowicz M J Wright I J | 2006 | Ecology2006，87，： | 1 |
| 6 | Phase differentiation via combined EBSD and XEDS 显示文摘 | Nowell M M Wright S I | 2004 | Journal of Microscopy2004，，213： | 1 |
| 7 | Bivariate line-fit- ting methods for allometry 显示文摘 | Warton D I Wright I J Falster D S | 2006 | Biological Reviews2006，81，： | 1 |
| 8 | The worldwide leaf economics spectrum显示文摘 | WRIGHT I J REICH P B WESTOB Y M | 2004 | Nature2004，428，： | 1 |
| 9 | Orientation imaging: the emergence of a new microscopy 显示文摘 | Adams B L Wright S I Kunze K | 1993 | Metall Trans1993，24，： | 1 |
| 10 | A sensitive ELISA technique for the diagnosis of Ana plasma marginale infeetions显示文摘 | Duzgun A Schuntner C A Wright I G | 1988 | Vet Parasitol1988，29，： | 1 |
| 11 | EBSD Image Quality Mapping 显示文摘 | Wright S I Nowell M M | 2006 | Microscopy and Microanalysis2006，12，1： | 1 |
| 12 | Transient pressure andvibration events resulting from high speed gas injection intoliquids显示文摘 | Taylor I F Wright J K Philp D K | 1988 | Canadian Metallurgical Quarterly1988，27，4： | 1 |
| 13 | The world- wide leaf economies spectrum显示文摘 | Wright I J Reich P B Westoby M | 2004 | Nature2004，428，： | 1 |
| 14 | Evidence of a general 2/3-power law of scaling leaf nitrogen to phosphorus among major plant groups and biomes 显示文摘 | REICH P B OLEKSYN J WRIGHT I J | 2010 | Proc R Soc B2010，277，： | 1 |
| 15 | Relationships among ecologically important dimensions of plant trait variation in seven neotropical forests 显示文摘 | Wright I J Ackerly D D Bongers F | 2007 | Annals of Botany2007，99，： | 1 |
| 16 | Characterization of the action of selected essential oil components on Gram-negative bacteria显示文摘 | Helander I M Alakomi H L Latva-Kala K Mattila-Sandholm T Pol I Smid E J Gorris L G M Wright A | 1998 | Journal of Agricultural and Food Chemistry1998，46，9： | 1 |
| 17 | Aheruative splicing in the vohage-gated sodium channel DmNav regulates activation, inactivation, and persistent cun'ent显示文摘 | LIN W H WRIGHT D E MURARO N I et ol | 2009 | Journal of Neu- rophysiology2009，102，3： | 1 |
| 18 | Strategy shifts in leaf physiology, structure and nutrient content between species of high- and low-rainfall and high- and low-nutrient habitats 显示文摘 | WRIGHT I J REICH P B WESTOBY M | 2001 | Functional Ecology2001，15，4： | 1 |
| 19 | The worldwide leaf economics spectrum 显示文摘 | Wright I J Reich P B Westoby M | 2004 | Nature2004，428，： | 1 |
| 20 | Calendar- and cycle-life studies of advanced technology development program generation 1 lithium-ion batteries显示文摘 | R.B Wright C.G Motloch J.R Belt J.P Christophersen C.D Ho R.A Richardson I Bloom S.A Jones V.S Battaglia G.L Henriksen T Unkelhaeuser D Ingersoll H.L Case S.A Rogers R.A Sutula | 2002 | Journal of Power Sources2002，，2： | 1 |
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