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| 1 | Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease:A controversial issue显示文摘Autophagy is a mechanism involved in cellular homeostasis under basal and stressed conditions delivering cytoplasmic content to the lysosomes for degradation to macronutrients.The potential role of autophagy in disease is increasingly recognised and investigated in the last decade.Nowadays it is commonly accepted that autophagy plays a role in the hepatic lipid metabolism.Hence,dysfunction of autophagy may be an underlying cause of non-alcoholic fatty liver disease.However,controversy of the exact role of autophagy in the lipid metabolism exists:some publications report a lipolytic function of autophagy,whereas others claim a lipogenic function.This review aims to give an update of the present knowledge on autophagy in the hepatic lipid metabolism,hepatic insulin resistance,steatohepatitis and hepatic fibrogenesis. | Wilhelmus J Kwanten Wim Martinet Peter P Michielsen Sven M Francque | 2014 | World Journal of Gastroenterology2014，20，23： | 17 |
| 2 | Challenges and prospects for consumer acceptance of cultured meat显示文摘Consumer acceptance of cultured meat is expected to depend on a wide diversity of determinants ranging from technologyrelated perceptions to product-specific expectations, and including wider contextual factors like media coverage, public involvement, and trust in science, policy and society. This paper discusses the case of cultured meat against this multitude of possible determinants shaping future consumer acceptance or rejection. The paper also presents insights from a primary exploratory study performed in April 2013 with consumers from Flanders(Belgium)(n=180). The concept of cultured meat was only known(unaided) by 13% of the study participants. After receiving basic information about what cultured meat is, participants expressed favorable expectations about the concept. Only 9% rejected the idea of trying cultured meat, while two thirds hesitated and about quarter indicated to be willing to try it. The provision of additional information about the environmental benefits of cultured meat compared to traditional meat resulted in 43% of the participants indicating to be willing to try this novel food, while another 51% indicated to be ‘maybe' willing to do so. Price and sensory expectations emerged as major obstacles. Consumers eating mostly vegetarian meals were less convinced that cultured meat might be healthy, suggesting that vegetarians may not be the ideal primary target group for this novel meat substitute. Although exploratory rather than conclusive, the findings generally underscore doubts among consumers about trying this product when it would become available, and therefore also the challenge for cultured meat to mimic traditional meat in terms of sensory quality at an affordable price in order to become acceptable for future consumers. | Wim Verbeke Pierre Sans Ellen J Van Loo | 2015 | Journal of Integrative Agriculture2015，14，2： | 10 |
| 3 | Diagnostic yield of small bowel capsule endoscopy depends on the small bowel transit time显示文摘AIM:To investigate whether the small bowel transit time(SBTT)influences the diagnostic yield of capsule endoscopy(CE).METHODS:Six hundred and ninety-one consecutive CE procedures collected in a database were analyzed.SBTT and CE findings were recorded.A running mean for the SBTT was calculated and correlated to the diagnostic yield with a Spearman's correlation test.Subgroup analyses were performed for the various indications for the procedure.RESULTS:There was a positive correlation between the diagnostic yield and SBTT(Spearman's rho 0.58,P <0.01).Positive correlations between diagnostic yield and SBTT were found for the indication obscure gastrointestinal bleeding(r=0.54,P<0.01),for polyposis and carcinoid combined(r=0.56,P<0.01)and for the other indications(r=0.90,P<0.01),but not for suspected Crohn's disease(r=-0.40).CONCLUSION:The diagnostic yield in small bowel capsule endoscopy is positively correlated with the small bowel transit time.This is true for all indications except for suspected Crohn's disease. | Jessie Westerhof Jan J Koornstra Reinier A Hoedemaker Wim J Sluiter Jan H Kleibeuker Rinse K Weersma | 2012 | World Journal of Gastroenterology2012，18，13： | 10 |
| 4 | 显示文摘 | Zhu Danqing Wim J van Ooij | 2004 | Progress in Organic Coat- ings2004，49，1： | 1 |
| 5 | 显示文摘 | Pan Guirong Dale W Schaefer Ooij Wim J van | 2006 | Thin Solid Films2006，515，4： | 1 |
| 6 | Determination of gasoline octane numbers from chemical composition 显示文摘 | Myers J M E Stollsteimer J Wims A M | 1975 | Anal Chem1975，47，13： | 1 |
| 7 | The prognostic value of histology in the assessment of patients with Budd–Chiari syndrome显示文摘 | Thjon J Tang Kenneth P Batts Piet C de Groen Bart van Hoek Elizabeth B Haagsma Wim C.J Hop Harry L.A Janssen | 2001 | Journal of Hepatology2001，，3： | 1 |
| 8 | IR Seeker Simulator and IR Scene Generation to Evaluate IR Decoy Effectiveness显示文摘 | Wim de Jong Frans A M Dam Gerard J Kunz | 2004 | SPIE Technologies for Optical Countermeasures2004，5615，： | 1 |
| 9 | Genetic organization and heterogeneity of the iceA locus of Helicobacter pylori显示文摘 | Céu Figueiredo Wim G.V Quint Ricardo Sanna Erwin Sablon John P Donahue Qing Xu Geraldine G Miller Richard M Peek Martin J Blaser Leen-Jan van Doorn | 2000 | Gene2000，，1： | 1 |
| 10 | Enhanced Corrosion Resistance of AA 2024-T3 and Hot-dip Galvanized Steel Using a Mixture of Bis- Tetrasulfide and Bis- Amine 显示文摘 | Zhu Danqing Wim J Van Ooij | 2004 | Elctrochimica Acta2004，，49： | 1 |
| 11 | A model for smooth viewing and navigation of large 2D information spaces显示文摘 | Jarke J Wan Wik Wim AA Nuij | | 0，，04： | 1 |
| 12 | The digestion of phosphate ore in phosphoric acid显示文摘 | Sietse van der S Yulia M Wim G J | 1987 | Ind Eng Chem Res1987，26，： | 1 |
| 13 | Rheology of mixtures of glutenin subfractions显示文摘 | AMATIA A TSIAMI A J WIM G M | 1997 | Journal of Cereal Science1997，26，： | 1 |
| 14 | Staging of carcinoid tumours with 18 F-DOPA PET: a prospective, diagnostic accuracy study显示文摘 | Klaas P Koopmans Elisabeth GE de Vries Ido P Kema Philip H Elsinga Oliver C Neels Wim J Sluiter Anouk NA van der Horst-Schrivers Pieter L Jager | 2006 | Lancet Oncology2006，，9： | 1 |
| 15 | Development of a lipase fermention process that uses a recombinant Psudomonas alcaligenes strain显示文摘 | GIJS G RONALD W J WIM J Q | 1998 | Appl Environ Microbio1998，64，7： | 1 |
| 16 | Corrosion protection of metals by water-based silane mixtures of his- amine and vinyltriacetoxysilane 显示文摘 | Danqing Zhu Wim J van Ooij | 2004 | Progress in Organic Coat- ings2004，49，： | 1 |
| 17 | Corrosion protection of metals by water-based silane mixtures of bis- amine and vinyltriacetoxysilane显示文摘 | Zhu D Q J van Ooij Wim | 2004 | Prog Org Coat2004，49，1： | 1 |
| 18 | Temperalure coefficient of resistivity of silicon and germanium near room temperature显示文摘 | Wim Bulllis F H Brewer C D Kolstad L J Swartzendruber | 1968 | Solid-State Electron1968，11，7： | 1 |
| 19 | Corrosion protection of metals by water - based silanemixtures of bis - amine and vinyltriacetoxysilane 显示文摘 | Danqing Zhu Wim J Van Ooij | 2004 | Progress in Organic Coatings2004，，49： | 1 |
| 20 | Model reduction of time-delay systems using position balancingand delay Lyapunov equations 显示文摘 | Elias J Tobias D Wim M | 2013 | Mathematics of Control Signals and Systems2013，25，2： | 1 |
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