|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Software for automated classification of probe-based confocal laser endomicroscopy videos of colorectal polyps显示文摘AIM:To support probe-based confocal laser endomi-croscopy (pCLE) diagnosis by designing software for the automated classification of colonic polyps. METHODS:Intravenous fluorescein pCLE imaging of colorectal lesions was performed on patients under-going screening and surveillance colonoscopies, followed by polypectomies. All resected specimens were reviewed by a reference gastrointestinal pathologist blinded to pCLE information. Histopathology was used as the criterion standard for the differentiation between neoplastic and non-neoplastic lesions. The pCLE video sequences, recorded for each polyp, were analyzed off-line by 2 expert endoscopists who were blinded to the endoscopic characteristics and histopathology. These pCLE videos, along with their histopathology diagnosis, were used to train the automated classification software which is a content-based image retrieval technique followed by k-nearest neighbor classification. The performance of the off-line diagnosis of pCLE videos established by the 2 expert endoscopists was compared with that of automated pCLE software classification. All evaluations were performed using leave-one-patient- out cross-validation to avoid bias. RESULTS:Colorectal lesions (135) were imaged in 71 patients. Based on histopathology, 93 of these 135 lesions were neoplastic and 42 were non-neoplastic. The study found no statistical significance for the difference between the performance of automated pCLE software classification (accuracy 89.6%, sensitivity 92.5%, specificity 83.3%, using leave-one-patient-out cross-validation) and the performance of the off-line diagnosis of pCLE videos established by the 2 expert endoscopists (accuracy 89.6%, sensitivity 91.4%, specificity 85.7%). There was very low power (< 6%) to detect the observed differences. The 95% confidence intervals for equivalence testing were:-0.073 to 0.073 for accuracy, -0.068 to 0.089 for sensitivity and -0.18 to 0.13 for specificity. The classification software proposed in this study is not a 'black box' but an informative tool based on the query by example model that produces, as intermediate results, visually similar annotated videos that are directly interpretable by the endoscopist. CONCLUSION:The proposed software for automated classification of pCLE videos of colonic polyps achieves high performance, comparable to that of off-line diagnosis of pCLE videos established by expert endoscopists. | Barbara André Tom Vercauteren Anna M Buchner Murli Krishna Nicholas Ayache Michael B Wallace | 2012 | World Journal of Gastroenterology2012，18，39： | 5 |
| 2 | Total pancreatectomy: Short- and long-term outcomes at a high-volume pancreas center显示文摘AIM To identify the current indications and outcomes of total pancreatectomy at a high-volume center. METHODS A single institutional retrospective study of patients undergoing total pancreatectomy from 1995 to 2014 was performed.RESULTS One hundred and three patients underwent totalpancreatectomy for indications including: Pancreatic ductal adenocarcinoma(n = 42, 40.8%), intraductal papillary mucinous neoplasms(n = 40, 38.8%), chronic pancreatitis(n = 8, 7.8%), pancreatic neuroendocrine tumors(n = 7, 6.8%), and miscellaneous(n = 6, 5.8%). The mean age was 66.2 years, and 59(57.3%) were female. Twenty-four patients(23.3%) underwent a laparoscopic total pancreatectomy. Splenic preservation and portal vein resection and reconstruction were performed in 24(23.3%) and 18 patients(17.5%), respectively. The 90 d major complications, readmission, and mortality rates were 32%, 17.5%, and 6.8% respectively. The 1-, 3-, 5-, and 7-year survival for patients with benign indications were 84%, 82%, 79.5%, and 75.9%, and for malignant indications were 64%, 40.4%, 34.7% and 30.9%, respectively.CONCLUSION Total pancreatectomy, including laparoscopic total pancreatectomy, appears to be an appropriate option for selected patients when treated at a high-volume pancreatic center and through a multispecialty approach. | Hazem M Zakaria John A Stauffer Massimo Raimondo Timothy A Woodward Michael B Wallace Horacio J Asbun | 2016 | World Journal of Gastrointestinal Surgery2016，8，9： | 3 |
| 3 | Nosocomial bloodstream infections in United States hospitals: a three-year analysis显示文摘 | EDMOND M B WALLACE S E MCCLISH D K | 1999 | Clin Infect1999，29，23： | 1 |
| 4 | Mitochondrially mediated synergistic cell killing by bile acids显示文摘 | Anabela P Rolo Carlos M Palmeira Kendall B Wallace | 2002 | BBA - Molecular Basis of Disease2002，，1： | 1 |
| 5 | Prolonged exposure of naive CD8+T cells to interleukin-7 or interleukin-15 stimulates proliferation without differentiation or loss of telomere length 显示文摘 | Wallace D L B~rard M Soares M V | 2006 | Immunology2006，119，2： | 1 |
| 6 | Near band edge Schottky barrier height modulation using high-κdielectric dipole tuning mechanism显示文摘 | COSS B E LOH W Y WALLACE R M | 2009 | Appl Phys Lett2009，95，22： | 1 |
| 7 | Detection of preinvasive cancer cells 显示文摘 | Backman V Wallace M B Perelman L T | 2000 | Nature2000，406，： | 1 |
| 8 | Characterization of the neurotrophic interaction between nerve growth facter and secreted alphaamloid precursor protein显示文摘 | Luo J J Wallace M S Hawver D B | 2001 | Neurosci Res2001，63，5： | 1 |
| 9 | Applications of Endoscopic Ultrasonography in Pancreatic Cancer显示文摘 | Varadarajulu S Wallace M B | 2004 | Cancer Control2004，11，1： | 1 |
| 10 | The roles of inhibin and gonadotropin-releasing hormone in the control of gonadotropin secretion in the ewe显示文摘 | Wallace J M Taylor P L | 1986 | J Endocrinology1986，111，： | 1 |
| 11 | Mechanically strong, electrically conductive, and biocompatible graphene paper显示文摘 | Chen H Q Muller M B Gilmore K J Wallace G G Li D | 2008 | Adv Mater2008，20，18： | 1 |
| 12 | Preliminary accuracy and interobserver agreement for the detection of intraepithelial neoplasia in barrett' s esophagus with probe-based confocal laser endomicroscopy 显示文摘 | Wallace M B Sharma P Lighdale C | 2010 | Gas- trointest Endosc2010，72，1： | 1 |
| 13 | Simulation of vertical position of buoyancy regulating Microcystis aeruginosa in a shallow eutrophic lake 显示文摘 | Wallace B B Bailey M C Hamilton D P | 2000 | Aquatic Science2000，62，： | 1 |
| 14 | Intraarterial platelet infusion for patients with intractable gastrointestinal hemorrhage and severe refractory thrombocytopenia显示文摘 | MADOFF D C WALLACE M J LICHTIGER B | 2004 | J Vasc Interv Radiol2004，15，： | 1 |
| 15 | Colonoscopy:new approaches to betteroutcomes显示文摘 | Coe S G Wallace M B | 2012 | Curr Opin Gastroenterol2012，28，1： | 1 |
| 16 | Effects of estradiol on ischemic factor-induced astrocyte swelling and AQP4 protein abundance显示文摘 | Rutkowsky J M Wallace B K Wise P M | 2011 | Am J Physiol Cell Physiol2011，301，1： | 1 |
| 17 | Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) in 2011,a Western perspective显示文摘 | Othman M O Wallace M B | 2011 | Clin Res Hepatol Gastroenterol2011，35，4： | 1 |
| 18 | Adriamycin-induced oxidative mi- tochondrial cardiotoxieity 显示文摘 | Berthiaume J M Wallace K B | 2007 | Cell Biol Toxicol2007，23，1： | 1 |
| 19 | Persistent alterations to thegene expression profile of the heart subsequent to chronicdoxorubicin treatment显示文摘 | Berthiaume J M Wallace K B | 2007 | Cardiovasc Toxicol2007，7，3： | 1 |
| 20 | Relationship of cortical thickness of the proximal humerus and pullout strength of a locked plate and screw construct显示文摘 | Wallace M J Bledsoe G Moed B R Israel H A Kaar S G | 2012 | J Orthop Trauma2012，26，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员