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| 1 | 聚乙二醇化干扰素a-2b治疗HBeAg阳性慢性乙型肝炎:HBsAg转阴与HBV基因型相关显示文摘HBsAg转阴是慢性乙型肝炎抗病毒治疗完全应答的纯正标志。方法为在一项多中心随机对照试验中,266例HBeAg阳性慢性乙型肝炎病人接受聚乙二醇化干扰素a-2b(100μg/d)联合拉米夫定(100mg/d)或安慰剂的治疗,疗程52wk;治疗结束后随访26wk。 | Flink HJ van Zonneveld M Hansen BE 陆伟(摘译) 张占卿(审校) | 2006 | 世界感染杂志2006，6，4： | 45 |
| 2 | IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treat- ment of Cancer Brain Tumor Group显示文摘 | van den Bent M J Dubbink HJ Marie Y Brandes AA Taphoorn MJ Wesseling P Frenay M Tijssen CC Lacombe D ldbaih A van Marion R Kros JM Dinjens WN Gorlia T. Sanson M. | 2010 | 中国神经肿瘤杂志2010，8，1： | 22 |
| 3 | Current and future therapies for inherited cholestatic liver diseases显示文摘Familial intrahepatic cholestasis(FIC) comprises a group of rare cholestatic liver diseases associated with canalicular transport defects resulting predominantly from mutations in ATP8B1, ABCB11 and ABCB4. Phe-notypes range from benign recurrent intrahepatic cholestasis(BRIC), associated with recurrent cholestatic attacks, to progressive FIC(PFIC). Patients often suffer from severe pruritus and eventually progressive cholestasis results in liver failure. Currently, first-line treatment includes ursodeoxycholic acid in patients with ABCB4 deficiency(PFIC3) and partial biliary diversion in patients with ATP8B1 or ABCB11 deficiency(PFIC1 and PFIC2). When treatment fails, liver transplantation is needed which is associated with complications like rejection, post-transplant hepatic steatosis and recurrence of disease. Therefore, the need for more and better therapies for this group of chronic diseases remains. Here, we discuss new symptomatic treatment options like total biliary diversion, pharmacological diversion of bile acids and hepatocyte transplantation. Furthermore, we focus on emerging mutation-targeted therapeutic strategies, providing an outlook for future personalized treatment for inherited cholestatic liver diseases. | Wendy L van der Woerd Roderick HJ Houwen Stan FJ van de Graaf | 2017 | World Journal of Gastroenterology2017，23，5： | 11 |
| 4 | CT筛查降低肺癌死亡率的随机试验显示文摘目前在曾经和现在吸烟的男性中,基于容积的低剂量计算机断层扫描(CT)筛查能否降低肺癌死亡率的随机试验证据有限。2020年初新英格兰医学杂志报道了一项来自欧洲的CT筛查对降低肺癌死亡率的临床试验结果。该研究招募了50~74岁的13195名男性(主要分析)和2594名女性(亚组分析),并将其随机分配至不筛查对照组和干预组,后者分别在基线、第1年、第3年和第5.5年进行CT筛查。通过荷兰和比利时国家登记处获得癌症诊断、死亡日期和死因。 | 王红(译) 唐威(译) 石菊芳(译) De Koning HJ Van der Aalst CM De Jong PA | 2020 | 中华预防医学杂志2020，54，7： | 5 |
| 5 | Musculoskeletal tumors :does fast dynamic contrast-enhanced subtract ion MR imaging contribute to the characterization显示文摘 | van der Woude HJ Verstraete KL Hogendoorn PC | 1998 | Radiology1998，208，3： | 1 |
| 6 | The role of high density lipoprotein in sepsis显示文摘 | van Leeuwen HJ van Beek AP Dallinga Thie GM | 2001 | Nerth J Med2001，59，3： | 1 |
| 7 | Orbital Graves' disease:A modifiation of the 'NOSPECS' classification显示文摘 | Van Dyk HJ | 1981 | Ophthalmology1981，88，6： | 1 |
| 8 | Muscu-loskeleteal tumors:does fast dynamic contrast-enhanced subtrac-tion MR imaging contribute to the characterization显示文摘 | van der Woude HJ Verstraete KL Hogendoorn PC | 1998 | Radiology1998，208，3： | 1 |
| 9 | Current treatments and future perspectives in colorectal and gastric cancer显示文摘 | Wilke HJ Van Cutsem E | 2003 | Ann Oncol2003，142，： | 1 |
| 10 | Morphology of the human internal vertebral venous plexus:a cadaver study after intravenous Araldite CY 221 injection显示文摘 | Groen RJ Groenewegen HJ Van Alphen HA | 1997 | Anat Rec1997，249，2： | 1 |
| 11 | Gout,just a nasty e-vent or a cardiovascular signal?A study from primary care显示文摘 | Janssens HJ van de Lisdonk EH Bor H | 2003 | Fam Pract2003，20，4： | 1 |
| 12 | Heart failure and incident late-life depression 显示文摘 | Luijendijk HJ Tiemeier H van den Berg JF | 2010 | J Am Geriatr Soc2010，58，8： | 1 |
| 13 | Pharmacokinetics of moxifloxacin in cerebrospinal fluid and plasma in patients with tubercu-lous meningitis显示文摘 | Alffenaar JWC van Altena R Bokkerink HJ | 2009 | Clin Infect Dis2009，49，7： | 1 |
| 14 | ESMO Consensus Guidelines for management of patients with colon and rectal cancer, a personalized approach to 'clinical decision making 显示文摘 | Schmoll HJ Van Cutsem E Stein A | 2012 | Ann 0ncol2012，23，10： | 1 |
| 15 | Radiological and electrocardiographic characterization of right ventricular outflow tract pacing显示文摘 | Bah JC van Hemel NM Wellens HJ | 2010 | Europace2010，12，12： | 1 |
| 16 | Lenient versus strict rate control in patients with atrial fibrillation 显示文摘 | Van Gelder IC Groenveld HF Crijns HJ | 2010 | N Engl J Med2010，362，15： | 1 |
| 17 | The role of lesional T cells in recalcitrant psoriasis during infliximab therapy显示文摘 | Bovenschen HJ Van De KerkhofPC Gerritsen WJ | | 0，，06： | 1 |
| 18 | Post-axillary dissection pain in breast cancer due to a lesion of the intercostobrachial nerve显示文摘 | Vecht CJ Van de Brand HJ Wajer OJ | 1989 | Pain1989，38，2： | 1 |
| 19 | Abdominal adhe- sions: intestinal obstruction, pain, and infertility 显示文摘 | Vrijland WW Jeekel J van Geldorp HJ | 2003 | Surg En- dose2003，17，7： | 1 |
| 20 | Contrast- induced nephropathy : pharmacology, pathophysiology and prevention显示文摘 | Geenen RW Kingma HJ van der Molen AJ | 2013 | Insights Imaging2013，4，6： | 1 |
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