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| 1 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 2 | Microstructure,chemical and tribological investigations of MoxW1-xSy co-sputtered composite films显示文摘 | YIN G L HUANG P H YU Z HE D N TU J P | 2006 | Tribology Letters2006，22，1： | 1 |
| 3 | 显示文摘 | Meng L Tu J P Liu M S | 1999 | Mater Lett1999，38，2： | 1 |
| 4 | New glycosides from Cistanche salsa 显示文摘 | Lei L Jiang Y Tu P F | 2007 | Helv Chim Acta2007，90，1： | 1 |
| 5 | A Fast Intensity-hue-saturation Fusion Technique with Spectral Adjustment for IKONOS Imagery显示文摘 | TU T M HUANG P S HUNG C L | 2004 | IEEE Geoscience and Remote Sensing Letters2004，1，4： | 1 |
| 6 | Electrochemical properties of Si/LiTi2O4 nanocomposite as anode materials for Li-ion secondary batteries显示文摘 | ZENG Z Y TU J P WANG X L ZHAO X B | 2008 | J Electroanal Chem2008，616，： | 1 |
| 7 | Effect of intermetallic compounds on the thermal fatigue of surface mount solder joints显示文摘 | Tu P L Chan Y C Lai J K L | 1997 | IEEE Transactions on Components Packaging and Manufacturing Technology Part B: Advanced Packaging1997，20，1： | 1 |
| 8 | Itosides J-N from ltoa ori- entalis and structure-anti-COX-2 activity relationship of phenolic glycosides 显示文摘 | TU P F CHAI X Y SONG Y L | 2005 | J Nat Prod2005，71，5： | 1 |
| 9 | Photooxidation of olefins under oxygen in platinum(II) complex-loaded mesoporous mole- cular sieves 显示文摘 | Feng K Zhang R Y Wu L Z Tu B Peng M L Zhang L P Zhao D Y Tung C H | 2006 | Journal of the American Chemical Society2006，128，14： | 1 |
| 10 | Self-assembled Synthesis of Hierarchical Nanostructured CuO with Various Morphologies and Their Application as Anodes for Lithium Ion Batteries显示文摘 | Xiang J Y Tu j P Zhang L | 2010 | Journal of Power Sources2010，195，1： | 1 |
| 11 | Inferior vena cava syndrome following percutaneous vertebroplasty with polymethylmethacrylate 显示文摘 | Kao F C Tu Y K Lai P L | 2008 | Spine2008，33，10： | 1 |
| 12 | Friction and wear behavior of Cu-Fe3Al powder metallurgical composites in dry sliding显示文摘 | Tu J P Meng L Liu M S | 1998 | Wear1998，220，1： | 1 |
| 13 | Phycobilin : cystein-84 biliprotein lyase, a near-universal lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins 显示文摘 | Zhao K H Su P Tu J M Wang X Liu H Ploscher M Eichacker L Yang B Zhou M Scheer H | 2007 | PNAS2007，104，14： | 1 |
| 14 | Tribological application of carbon nanotubes in metal-based carbon nanotubes composite coating and composites 显示文摘 | CHEN W X TU J P WANG L Y | 2003 | Carbon2003，41，： | 1 |
| 15 | Intelligent predictive decision support system for condition-based maintenance显示文摘 | Yam R C M Tse P W Li L Tu P | 2001 | International Journal of Advanced Manufacturing Technology2001，17，5： | 1 |
| 16 | Electrodeposition of Ni-Co alloys from a deep eutectic solvent 显示文摘 | You Y H Gu C D Wang X L Tu J P | 2012 | Surface and Coatings Technology2012，206，17： | 1 |
| 17 | An investigation on tribological properties of graphite nanosheets as oil additive显示文摘 | Huang H D Tu J P Gan L P | 2006 | Wear2006，261，： | 1 |
| 18 | Laboratory Investigation of Impulse Characteristics of Transmission Tower Grounding Devices 显示文摘 | J L He R Zeng Y P Tu J Zou S M Chen Z C Guan | 2003 | IEEE Transactions on Power Delivery (S0885-8977)2003，18，3： | 1 |
| 19 | Tribological application of carbon nanotubes in a metal-based composite coating and composites显示文摘 | Chen W X Tu J P Wang L Y | 2003 | Carbon2003，41，2： | 1 |
| 20 | Formation of pyrite thin films by sulfidation annealing of iron films 显示文摘 | MENG L TU J P LIU M S | 1999 | Materials Letters1999，38，2： | 1 |
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