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| 1 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 2 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 3 | Does board gender diversity affect firm performance?Empirical evidence from Standard & Poor’s 500 Information Technology Sector显示文摘The essence of this study is to investigate the influence of the board gender diversity on firms’accounting and market-based performance using a sample of Standard&Poor’s 500 companies belonging to the information technology sector over 12 years.Using the pooled ordinary least squares(OLS)method,the outcomes provide evidence for a positive influence of women on corporate boards on both measures of company performance,except for the percentage of female executives in the case of return on assets(ROA).After estimating the fixed effects and random-effects through panel data,the econometric outcomes show no statistically significant association among board gender diversity and ROA but a positive influence of the number and percentage of women on board on price-to-earnings ratio. | Liliana Nicoleta Simionescu Ştefan Cristian Gherghina Hiba Tawil Ziad Sheikha | 2021 | Financial Innovation2021，7，1： | 2 |
| 4 | Sinus floor elevation using a bovine bone mineral(Bio--Oss)with or without the concomitant use of a bilayered collagen birrier(Bio--Gide): a clinical report of immediate and delayed implant placement显示文摘 | Tawil G Mawla M | 2001 | Int J Oral Maxillofae Implants2001，16，5： | 1 |
| 5 | Adaptation to fat markedly increases pancreatic secretory response to intraduodenal fat in rats显示文摘 | Spannagel AW Nakano I Tawil T | 1996 | Am J Physiol1996，270，11： | 1 |
| 6 | Posttraumatic cerebral infarc- tion: incidence, outcome, and risk factors 显示文摘 | Tawil I Stein D M Mirvis S E | 2008 | J Trauma2008，64，4： | 1 |
| 7 | Alkali fusion of zir- con sand 显示文摘 | Barawy K A E Tawil S Z E and Francis A A | 2000 | Mineral Processing and Extractive Metallurgy2000，109，1： | 1 |
| 8 | Tracheal schwan- noma: a misleading entity显示文摘 | Hamdan A 1 Moukarbel R V Tawil A | 2010 | Middle East J Anesthesiol2010，20，4： | 1 |
| 9 | Manage- ment of inguinal hernia in premature infants: 10-year ex- perience显示文摘 | Crankson SJ A1 Tawil K A1 Namshan M | 2015 | J Indian Assoc Pediatr Surg2015，20，1： | 1 |
| 10 | The Neurological Outcome of Isolated PVL and Severe IVH in Preterm Infants:Is It Fair to Compare?显示文摘 | Al Rifai MT Al Tawil KI | 2015 | Pediatr Neurol2015，53，5： | 1 |
| 11 | Dilhydropyridine receptor mutations cause hypokalemic periodic paralysis显示文摘 | Ptacek LJ Tawil R Griggs RC | 1994 | Cell1994，77，6： | 1 |
| 12 | Strategies for insulin initiation: insights from the French LIGHT observational study显示文摘 | Verges B Brun JM Tawil C | 2012 | Diabetes Metab Res Rev2012，28，： | 1 |
| 13 | Symptomatic Spontaneous Pneumothorax in Term newborn infants显示文摘 | KHALIL AL TAWIL | 2004 | Pediatr Pulmonol2004，37，： | 1 |
| 14 | Zinc supplementation tightens leaky gut in Crohn’s disease显示文摘 | A.M.El‐Tawil | 2012 | Inflamm Bowel Dis2012，，2： | 1 |
| 15 | Tracheal schwanno- ma: a misleading entity显示文摘 | Fiamdan AL Moukarbel R~ Tawil A | 2010 | Middle East J Anaesthesiol2010，20，4： | 1 |
| 16 | Integrin a3hl can promote adhesion and spreading of metastatic breast carcinoma cells on the lymph node stroma显示文摘 | Tawil NJ Gowri V Djoneidi M | 1996 | Int J Cancer1996，66，5： | 1 |
| 17 | Posttraumatic cerebral infarction: incidence, outcome and risk factors 显示文摘 | Tawil I Stein DM Mirvis SE | 2008 | J Trauma2008，64，4： | 1 |
| 18 | Facioscapulohumeral muscular dystrophy: molecular pathological advances and future directions 显示文摘 | Statland JM Tawil R | 2011 | Curr Opin Neurol2011，24，5： | 1 |
| 19 | Clinical evaluation of short, machined -sur- face implants followed for 12 to 92 months显示文摘 | Tawil G Younan R | 2003 | Int J Oral Maxillo- fac Implans2003，18，6： | 1 |
| 20 | Peripherally inserted central venous catheters in newborn infants:malpositioning and spontaneous correction of catheter tips显示文摘 | Tawil KA Eldemerdash A Hathlol KA | | 0，，01： | 1 |
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