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| 1 | Synthesis of iso-DDA, member of a novel class of anti-HIV agents 显示文摘 | HURYN D M SLUBOSKI 13 C TAM S Y | 1989 | Tetrahedron Lett1989，30，46： | 1 |
| 2 | Hyperproduction of IL-23 and IL- 17 in patients with systemic lupus erythematosus: Implications for Thl7- mediated inflammation in autoimmunity 显示文摘 | Wang C K Lit L C W Tam L S | 2008 | Clin Immunol2008，127，3： | 1 |
| 3 | Microbial population dynamics and enzyme activities during composting 显示文摘 | Tiquia S M Wan J H C Tam N F Y | 2002 | Compost Science and Utilization2002，10，2： | 1 |
| 4 | Comparative analyses of genetic diversities within tomato and pepper collections detected by retrotransposon-based S-SAP,AFLP and SSR显示文摘 | Tam S M Mhiri C Vogelaar A | 2005 | Theor Appl Genet2005，110，5： | 1 |
| 5 | Microbial population dynamics and enzyme activities during omposting 显示文摘 | Tiquia S M Wan J H C Tam N F Y | 2002 | Compost Science and Utilization2002，10，2： | 1 |
| 6 | Properties of concrete made with crushed concrete as coarse aggregate显示文摘 | Ravindrarajah R S Tam C T | 1985 | Magazine ofConcrete Research1985，37，130： | 1 |
| 7 | Culture as common sense:Perceived consensus versus personal beliefs as mechanisms of cultural influence显示文摘 | Zou X Tam K Morris M.W Lee S Lau I.Y & Chiu C | | 0，，04： | 1 |
| 8 | Comparative analyses of genetic diversities within tomato and pepper collections detected by retrotransposon-based SSAP, AFLP and SSR显示文摘 | TAM S M MHIRI C VOGELAAR A KERKVELD M PEARCE S R GRANDBASTIEN MA | 2005 | Theor Appl Genet2005，110，： | 1 |
| 9 | The biological activities of trichosanatin after coupling to dextran显示文摘 | KO W H YEUNG H W TAM S C | 1993 | Gen Pharmacol1993，24，3： | 1 |
| 10 | Synthesis and anti-HIV activity of isonucleosides显示文摘 | HURYN D M SLUBOSKI B C TAM S Y | 1992 | J Med Chem1992，35，13： | 1 |
| 11 | Microstructure of dilute hydrophobically modified alkali soluble emulsion in aqueous salt solution 显示文摘 | Dai S Tam K C Jenkins R D | 2000 | Macromolecules2000，33，2： | 1 |
| 12 | Influence of the thermal effect on the TEM00 mode output power of a laser-diode side-pumped solid-state laser显示文摘 | Xie W J Tam S C Lam Y L | 2000 | Appl Opt2000，39，30： | 1 |
| 13 | Relationship between Cooperation Net-works and Innovation Performance of SMEs显示文摘 | Zeng S X Xie X M Tam C M | 2010 | Technovation2010，30，3： | 1 |
| 14 | Products of ozone-initiated chemistry in a simulated aircraft environment显示文摘 | Wisthaler A Tamás G Wyon D P Strφm-Tejsen P Space D Beauchamp J Hansel A M(a)rk T D Weschler C J | | 0，，13： | 1 |
| 15 | Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation显示文摘 | Burgel P R Lazarus S C Tam D C | 2001 | J Immunol2001，167，： | 1 |
| 16 | Mineral Fertilizer Management of Maize on Farmer Fields Differing in Organic Inputs in the West African Savanna显示文摘 | Wopereis M C S Tamélokpo A Ezui K | 2006 | Field Crops Research2006，96，23： | 1 |
| 17 | Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization显示文摘 | Gunn MD Kyuwa S Tam C | 1999 | J Exp Med1999，189，： | 1 |
| 18 | Interaction between fluorocarbon end-capped poly(ethylene oxide) and cyclodextrins显示文摘 | Liao D Dai S Tam K C | 2007 | Macromolecules2007，40，8： | 1 |
| 19 | Pluronic L-81 ameliorates diabetic symptoms in db/db mice through transcriptional regulation of microsomal triglyceride transfer protein显示文摘AIM: To test whether oral L-81 treatment could im-prove the condition of mice with diabetes and to investigate how L-81 regulates microsomal triglyceride transfer protein (MTP) activity in the liver. METHODS: Genetically diabetic (db/db) mice were fed on chow supplemented with or without L-81 for 4 wk. The body weight, plasma glucose level, plasma lipid profile, and adipocyte volume of the db/db mice were assessed after treatment. Toxicity of L-81 was also evaluated. To understand the molecular mecha-nism, HepG2 cells were treated with L-81 and the effects on apolipoprotein B (apoB) secretion and mRNA level of the MTP gene were assessed.RESULTS: Treatment of db/db mice with L-81 sig-nificantly reduced and nearly normalized their body weight, hyperphagia and polydipsia. L-81 also markedly decreased the fasting plasma glucose level, improved glucose tolerance, and attenuated the elevated levels of plasma cholesterol and triglyceride. At the effective dosage, little toxicity was observed. Treatment of HepG2 cells with L-81 not only inhibited apoB secretion, but also signif icantly decreased the mRNA level of the MTP gene. Similar to the action of insulin, L-81 exerted its effect on the MTP promoter. CONCLUSION: L-81 represents a promising candidate in the development of a selective insulin-mimetic mol-ecule and an anti-diabetic agent. | Wo-Shing Au Li-Wei Lu Sidney Tam Otis King Hung Ko Billy KC Chow Ming-Liang He Samuel S Ng Chung-Man Yeung Ching-Chiu Liu Hsiang-Fu Kung Marie C Lin | 2009 | World Journal of Gastroenterology2009，15，24： | 1 |
| 20 | Reaction and spectroscopic studies of sodium salt catalysts for lactic acid conversion 显示文摘 | TAM M S GUNTER G C CRACIUM R | 1997 | Ind Eng Chem Res1997，36，： | 1 |
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