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| 1 | Prognostic value of pre-treatment F-18-FDG PET-CT in patients with hepatocellular carcinoma undergoing radioembolization显示文摘AIM To evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver radioembolization.METHODS We identified 34 patients with HCC who underwent an FDG PET/CT scan prior to hepatic radioembolization at our institution between 2009 and 2013. Patients wereseen in clinic one month after radioembolization and then at 2-3 mo intervals. We assessed the influence of FDG tumor uptake on outcomes including local liver control(LLC), distant liver control(DLC), time to distant metastases(DM), progression free survival(PFS) and overall survival(OS).RESULTS The majority of patients were males(n = 25, 74%), and had Child Pugh Class A(n = 31, 91%), with a median age of 68 years(46-84 years). FDG-avid disease was found in 19(56%) patients with SUVmax ranging from 3 to 20. Female patients were more likely to have an FDG-avid HCC(P = 0.02). Median follow up of patients following radioembolization was 12 months(1.2-62.8 mo). FDG-avid disease was associated with a decreased 1 year LLC, DLC, DM and PFS(P < 0.05). Using multivariate analysis, FDG avidity predicted for LLC, DLC, and PFS(all P < 0.05).CONCLUSION In this retrospective study, pre-treatment HCC FDGavidity was found to be associated with worse LLC, DLC, and PFS following radioembolization. Larger studies are needed to validate our initial findings to assess the role of F-18-FDG PET/CT scans as biomarker for patients with HCC following radioembolization. | Yazan Abuodeh Arash O Naghavi Kamran A Ahmed Puja S Venkat Youngchul Kim Bela Kis Junsung Choi Benjamin Biebel Jennifer Sweeney Daniel A Anaya Richard Kim Mokenge Malafa Jessica M Frakes Sarah E Hoffe Ghassan El-Haddad | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 2 | 强化与标准降压治疗对脑卒中亚型的影响显示文摘在收缩压干预试验(systolic blood pressure intervention trial, SPRINT)中,各治疗组的脑卒中发生比例差异无统计学意义,但脑卒中亚型的病因不同,可能对强化降压治疗的反应不同。SPRINT纳入患者(n=9 361)随机分为目标收缩压<120 mm Hg(1 mm Hg=0.133 kPa)的强化治疗与目标收缩压<140 mm Hg的标准治疗组。 | Wright CB Auchus AP Lerner A Ambrosius WT Ay H Bates JT Chen J Meschia JF Pancholi S Papademetriou V Rastogi A Sweeney M Willard JJ Yee J Oparil S 赵狄(摘译) 郑武洪(审校) | 2021 | 中华高血压杂志2021，29，3： | 2 |
| 3 | Sand dunes as potential sources of dust in northern China显示文摘While saltation bombardment of sand grains on a fine substrate can produce considerable dust, the well-sorted nature of sand dunes tends to preclude them from consideration as major dust sources. Recent research, however, has revealed that sand dunes can, in some cases, be large sources of dust. We used the PI-SWERL(Portable In-Situ Wind Erosion Laboratory) to measure in the field the potential of sand dunes and other desert landforms to emit particulate matter <10 μm(PM-10) dust in the Tengger, Ulan Buh, and Mu Us deserts of northern China. Combined with high resolution particle size measurements of the dune sand, an assessment of sand dunes as a dust source can be made. Large active transverse dunes tend to contain little to no stored PM-10, yet they produce a low dust flux. Coppice dunes stabilized by vegetation contain appreciable PM-10 and have very high dust emission potential. There is a positive correlation between the amount of PM-10 stored in a dune and its potential dust flux. Saltation liberates loose fines stored in dunes, making them very efficient dust emitters compared to landforms such as dry lake beds and washes where dust particles are unavailable for aeolian transport due to protective crusts or sediment cohesion. In cases where large dunes do not store PM-10 yet emit dust when active, two hypotheses can be considered:(1) iron-oxide grain coatings are removed during saltation, creating dust, and(2) sand grains collide during saltation, abrading grains to create dust. Observations reveal that iron oxide coatings are present on some dune sands. PI-SWERL data suggests that low dust fluxes from dunes containing no stored dust may represent an estimate for the amount of PM-10 dust produced by removal of iron oxide coatings. These results are similar to results from dunes in the United States. In addition, PI-SWERL results suggest that dust-bearing coppice dunes, which cover vast areas of China's sandy deserts, may become major sources of dust in the future if overgrazing, depletion of groundwater, or drought destabilizes the vegetation that now partially covers these dunes. | Mark R SWEENEY LU HuaYu CUI MengChun Joseph A MASON FENG Han XU ZhiWei | 2016 | Science China Earth Sciences2016，59，4： | 2 |
| 4 | How Functional, Psychological, and Social Relationship Benefits Influence Individual and Firm Commitment to the Relationship显示文摘 | JILLIAN SWEENEY DAVID A WEBB | 2007 | Journal of Business & Industrial Marketing2007，22，7： | 1 |
| 5 | The mechanism of myosin Ⅵ translocation and its loadinduced anchoring显示文摘 | ALTMAN D SWEENEY H L SPUDICH J A | 2004 | Cell2004，116，5： | 1 |
| 6 | The effect of enclosure size on social interactions and daily activity patterns of the captive Asiatic wild horse (Equus przewalskii)显示文摘 | Hogan E S Houpt K A Sweeney K | 1988 | Applied Animal Behaviour Science1988，21，12： | 1 |
| 7 | Stochastic modeling of electrical treeing: Fractal and statistical charac teristics显示文摘 | Barclay A L Sweeney P J Dissado L A | 1990 | J Phys D: Appl Phys1990，23，： | 1 |
| 8 | Specific pathogenfree Penaeus vannamei 显示文摘 | Wyban J A Swingle J S Sweeney J N | 1995 | World Aquaculture1995，24，： | 1 |
| 9 | Evidence against an X-linked locus close to DXS7 determining visual loss susceptibility in British and Italian families with Leber hereditary optic neuropathy 显示文摘 | Sweeney MG Davis MB Lashwood A | 1992 | Am J Hum Genet1992，51，： | 1 |
| 10 | Effects of the reactive oxygen species hydrogen peroxide and hypochlorite on endothelial nitric oxide production显示文摘 | Jaimes E A Sweeney C Raij L | 2001 | Hypertension2001，38，4： | 1 |
| 11 | Severe vs moderate energy restriction with and without exercise in the treatment of obesity:efficiency of weight loss显示文摘 | SWEENEY M E HILL J O HELLER P A | 1993 | Am J Clin Nut1993，57，： | 1 |
| 12 | A chemical kinetic model of vitrinite maturation and reflectance显示文摘 | BURNHAM A K SWEENEY J | 1989 | Geochimica et Cosmo- chimica Acta1989，53，10： | 1 |
| 13 | Distinguishing be- nign from malignant adrenal masses : multi - detector row CT pro- tocol with 10-minute delay 显示文摘 | Blake M A Kalra M K Sweeney A T | 2006 | Radiology2006，238，2： | 1 |
| 14 | Stress-dependent regu-lation of FOXO transcription factors by the SIRTl deacetylase显示文摘 | Brunet A Sweeney LB Sturgill JF etal | 2004 | Science2004，303，5666： | 1 |
| 15 | TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers显示文摘 | Singh A Sweeney MF Yu M | 2012 | Cell2012，148，4： | 1 |
| 16 | Addtion of L-carnitine to additive solution-suspended red cell stored at 40C reduces in vitrohemolysis and improves in vivo viability显示文摘 | Arduine A Holme S Sweeney JD | | 0，，： | 1 |
| 17 | Detecting Earnings Management显示文摘 | Dechow P R Sloan A Sweeney | 1995 | The Accounting Review1995，，70： | 1 |
| 18 | Reproductive system function in women cross-country rurmers显示文摘 | WAKAT D K SWEENEY K A ROGOL A D | 1982 | Med Sci Sports Exerc1982，14，2： | 1 |
| 19 | Country village weekend breaks: Experience in Wales显示文摘 | MCMANUS P SWEENEY A E GEEN A G | 1995 | Tourism Manage ment1995，16，2： | 1 |
| 20 | Detecting earnings management 显示文摘 | Dechow P M Sloan R G Sweeney A P | 1995 | The Accounting Review1995，70，： | 1 |
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