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| 1 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016,19,9: | 10 |
| 2 | National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed. | Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun | 2012 | World Journal of Gastroenterology2012,18,32: | 8 |
| 3 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 8 |
| 4 | Phenotypic instability and rapid gene silencing in newly formed Arabidopsis alloteraploids显示文摘 | Comai L Tyagi A P Winter K Holmes-Davis R Reynolds S H Stevens Y Byers B | 2000 | Plant Cell2000,12,9: | 2 |
| 5 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003,,8: | 2 |
| 6 | Haplotype analysis of the polymorphic human vascular endothelial growth factor gene promoter显示文摘 | STEVENS A SODEN J BRENCHLEY P E | 2003 | Cancer Res2003,63,: | 1 |
| 7 | Investigating Semantic Similarity Measures Across the Gene Ontology: The Relationship Between Sequence and Annotation 显示文摘 | Lord P W Stevens R D Brass A | 2003 | Bioinformatics2003,19,10: | 1 |
| 8 | A capripoxvirus detection PCR and antibody ELISA based on the maior antigen P32, the homolog of the vaccinia virus H3L gene 显示文摘 | Heine H G Stevens M P Foord A J | 1999 | J Immune Meth1999,277,: | 1 |
| 9 | Telomere length is shorter in healthy offspring of subjects with coronary artery disease: support for the telomere hypothesis显示文摘 | Brouilette SW Whittaker A Stevens SE van der Harst P Good- all AH Samani NJ | 2008 | Heart2008,94,4: | 1 |
| 10 | Estimating the distribution of snow water equivalent using remotely sensed snow cover data and a spatially distributed snowmelt model:A multi-resolution,multi-sensor comparison显示文摘 | NOAH P M STEVEN A M | | 0,,: | 1 |
| 11 | Radiation-induced epigenetic DNA methylation modification of radiation-response pathways显示文摘 | Deborah A Antwih Kristina M Gabbara Wayne D Lancaster Douglas M Ruden Steven P Zielske | 2013 | Epigenetics2013,,8: | 1 |
| 12 | Procedural outcomes and long-term survival among patients undergoing percutaneous coronary intervention of a chronic total occlusion in native coronary arteries:a 20-year experience显示文摘 | James A Suero MD Steven P | 2001 | Indian Heart J2001,53,6: | 1 |
| 13 | Symbolic or substantive document? The influence of ethics codes on financial executives' decisions显示文摘 | Stevens J M Steensma H K Harrison D A Cochran P L | | 0,,2: | 1 |
| 14 | Synthesis of a fluorescent derivatizatizing reagent 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate and its application for the analysis of hydrolysate amino acids via high-performance liquid chromatography显示文摘 | Steven A C Dennis P M | 1993 | Anal Biochem1993,211,: | 1 |
| 15 | Mapping and analysis of changes in the riparian landscape structure of the Lockyer Valley catchment Queensland, Australia显示文摘 | Armando A A Steven R R Mark S P | | Landscape and Urban Planning0,59,: | 1 |
| 16 | A Simple Method for Calibra- ting Force Plates and Force Treadmills Using an Instrumented Pole 显示文摘 | Steven H C Peter G A Daniel P F | 2009 | Gait and Posture2009,29,: | 1 |
| 17 | Staging laparoscopy with laparoscopic ultrasonography: optimizing resectability in hepatobiliary and pancreatic malignancy显示文摘 | Mark P Callery Steven M Strasberg Gerard M Doherty Nathaniel J Soper Jeffrey A Norton | 1997 | Journal of the American College of Surgeons1997,,1: | 1 |
| 18 | Development of branching in living radical copolymerization of vinyl and divinyl monomers显示文摘 | Iveta B Norman C B Steven P A | 2006 | Macromolecules2006,39,22: | 1 |
| 19 | Channel of distribution profits when channel members form conjectures显示文摘 | Jeuland A P Steven M S | 1988 | Marketing Science1988,7,2: | 1 |
| 20 | A quantitative shape analysis of organic templates employed in zeolite synthesis显示文摘 | Boyett R E Stevens A P Ford M G | 1996 | Zeolites1996,17,56: | 1 |