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285篇 您的检索式:作者名="Stephens C D"
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1Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome显示文摘BackgroundThere 是在质子泵禁止者(PPI ) 和 clopidogrel 之间的可能的不利相互作用上的大争论。另外, PPI 的使用是否少些影响 ticagrelor 遗体的临床的功效,知道。在经皮的冠的干预(一种总线标准) .MethodsWe 回顾地从 “ 分析了数据以后,我们试图与急性冠的症候群(交流)在病人在临床的结果上决定 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响;真实 world” ;,国际,在 2003 和 2014 之间的多中心登记( n = 15,401 )并且在1年的合成主要端点上估计了 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响(所有原因死亡收到 PPI 的病人更老,更经常女性,并且是更可能的有 comorbidities。没有协会为收到 clopidogrel 的病人在 PPI 使用和主要端点之间被观察(调整 HR:1.036;95% CI:0.903-1.189 ) 或 ticagrelor (调整 HR:2.320;95% CI:0.875-6.151 )(P 相互作用 = 0.2004 ) 。同样, PPI 的使用没与所有原因死亡,重新梗塞,或与交流后面的一种总线标准的为与任何一个 clopidogrel 对待的病人或 ticagrelor.ConclusionsIn 病人的严重流血的减少的风险的增加的风险被联系, PPI 的伴随物使用没在收到 clopidogrel 或 ticagrelor 的病人与不利结果的增加的风险被联系。我们的调查结果显示与 clopidogrel 或 ticagrelor 在联合使用 PPI 是合理的,特别在有胃肠的流血的更高的风险的病人。Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzfilez-Juanatey Stephen B Wilton Wouter J Kikkert Ivlin Nufiez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiril Sasko Kedev 2016Journal of Geriatric Cardiology2016,13,3:12
2P2Y12受体抑制剂联合质子泵抑制剂对急性冠脉综合征患者缺血事件影响的临床分析显示文摘目的本研究旨在分析P2Y12受体抑制剂联合质子泵抑制剂(PPI)治疗对经皮冠状动脉介入(PCI)术后的急性冠脉综合征患者缺血事件的影响。方法基于国际多中心回顾性注册登记研究,纳入2003至2014年因急性冠脉综合征人院行PCI术的患者,分为PPI组及非PPI组并随访1年,主要临床终点为全因死亡/再发心肌梗死的复合终点。根据P2Y12受体抑制剂种类,将入组患者分为氯吡格雷组及替格瑞洛组,并比较不同药物与PPI联用发生临床终点事件的风险。结果研究入选9429例患者,PPI组占54.8%,具有更多高危因素。Cox回归结果提示PPI组较非PPI组全因死亡/再发心肌梗死复合事件的发生差异无统计学意义(HR1.00,95%CI 0.86—1.18)。根据P2Y12抑制剂种类不同分为氯吡格雷组和替格瑞洛组,不同P2Y12受体抑制剂联用PPI较未联用PPI患者的临床终点无差异,联用PPI的氯吡格雷组与替格瑞洛组的临床终点差异也无统计学意义。结论急性冠脉综合征患者PPI与P2Y12受体抑制剂联用不增加全因死亡和再发心肌梗死风险,尤其PPI联用氯吡格雷在患者的缺血事件上与替格瑞洛比较差异无统计学意义。冯斯婷 严妍 范婧尧 王晓 郑文 聂绍平 Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D' Ascenzo Jorge Saucedo Jose R Conzalez-Juanatey Stephen B Wilton Wouter J Kikkert Ivan Nunez-Gil Albert Ariza-Sole Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiri Sasko Kedev 2016中华医学杂志2016,96,33:6
3Global malaria mortality between 1980 and 2010: a systematic analysis显示文摘Christopher JL Murray Lisa C Rosenfeld Stephen S Lim Kathryn G Andrews Kyle J Foreman Diana Haring Nancy Fullman Mohsen Naghavi Rafael Lozano Alan D Lopez 2012The Lancet2012,,9814:2
4Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D 2013Clinical Chemistry2013,,1:2
5Human CD4 (+) CD25 (+) thymoeytes and peripheral T cells have immune suppressive activity in virto 显示文摘Stephen LA Mottet C Mason D etal 2001Eur J Immunol2001,31,:1
6Pancreatic lesions in yon Hippel-Lindau disease: prevalence, clinice significance, and CT findings 显示文摘Hough D M Stephens D H Johnson C D 1994Am J Roentgenol1994,162,5:1
7Extension of Polygroups by Polygroups and Their Representations Using Colour Schemes 显示文摘STEPHEN D C 1983Univer sal Algebra and Lattice Theory1983,1004,:1
8Postoperative pain assessment in the neonatal intensive care unit 显示文摘MeNair C Ballantyne M Dionne K Stephens D Stevens B 2004Arch Dis Child Fetal Neonatal Ed2004,89,6:1
9Haplotype variation and linkage disequilibrium in 313 human genes显示文摘Stephens J C Schneider J A Tanguay D A 2001Science2001,293,:1
10Human CD4^+CD25^+ thymocytes and peripheral T cells have immune suppressive activity in vitro显示文摘Stephens L A Mottet C Mason D 2001Eur J Immunol2001,31,4:1
11Host-microbe interactions:shaping the evolution of the plant immune response显示文摘Stephen T C Gitta C Brad D Brian J S 2006Cell2006,124,4:1
12Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars 显示文摘Cavanagh CS Chao S Wang BE Huang BE Stephen S Kiani S Forrest K Saintenac C Brown-Guedira GL Akhunova A See D Bai G Pumphrey M Tomar L Wong D Kong S Reynolds M da Silva ML Bockelman H Talbert L Anderson JA Dreisigacker S Baenziger S Carter A Korzun V Morrell PL Dubcovsky J Morell MK Sorrells ME Hayden MJ Akhunov E 2013PNAS2013,110,:1
13A binary search heuristic algorithm based on randomized local search for the rectangular strip packing problem显示文摘Zhang D F Wei L J Stephen C H 2013Informs Journal on Computing2013,25,2:1
14Understanding the Char- acteristics of Quality for Software Engineering Processes : A Grounded Theory Investigation 显示文摘TRENT A K NEIL J D STEPHEN C C 2014Information and Software Technology2014,56,2:1
15Optimization of a 3' -minor groove binder-DNA probe targeting the uidA gene for rapid identification of Escherichia coli O157:H7 using real-time PCR 显示文摘Ken J Yoshitomi Karen C Jinneman Stephen D Weagant 2003Molecular and Cellular Probes2003,,17:1
16Specific genomic fingerprints of phytopathogenic Xanttzomonas and Pseudomonas pathovars and strains generated with repeti tive sequences and PCR显示文摘Louws F J Fulbright D W Stephens C T 1994Applied and Environmental Microbiology1994,60,7:1
17Multiplex real-time PCR method to identify shiga toxin genes stx1 and stx2 and escherichia coli O157: H7/Hserotype显示文摘KAREN C J KEN J Y STEPHEN D W 2003Applied and Environmental Microbiology2003,69,10:1
18Human CD44^+ CD25^+ thymocytes and peripheral T cells have immune suppressive activity in vitro 显示文摘Stephens LA Mottet C Mason D 2001Eur J Immunol2001,31,4:1
19Haplotype variation and linkage disequilibrium in 313 human genes显示文摘STEPHEN J C SCHNEIDER J A TANGUAY D A 2001Science2001,293,5529:1
20Pharmacokineti cs of an oral solution of the microemulsion formulation of cyclosporine in main tenance pediatric liver transplant recipients显示文摘Stephen D Gerard C John S 1997Transplantation1997,63,12:1
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