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| 1 | Embolization of splenorenal shunt associated to portal vein thrombosis and hepatic encephalopathy显示文摘Hepatic encephalopathy(HE)is a cognitive disturbance characterized by neuropsychiatric alterations.It occurs in acute and chronic hepatic disease and also in patients with portosystemic shunts.The presence of these portosystemic shunts allows the passage of nitrogenous substances from the intestines through systemic veins without liver depuration.Therefore,the embolization of these shunts has been performed tocontrol HE manifestations,but the presence of portal vein thrombosis is considered a contraindication.In this presentation we show a cirrhotic patient with severe HE and portal vein thrombosis who was submitted to embolization of a large portosystemic shunt.Case report:a 57 years-old cirrhotic patient who had been hospitalized many times for persistent HE and hepatic coma,even without precipitant factors.She had a wide portosystemic shunt and also portal vein thrombosis.The abdominal angiography confirmed the splenorenal shunt and showed other shunts.The larger shunt was embolized through placement of microcoils,and the patient had no recurrence of overt HE.There was a little increase of esophageal and gastric varices,but no endoscopic treatment was needed.Since portosystemic shunts are frequent causes of recurrent HE in cirrhotic patients,portal vein thrombosis should be considered a relative contraindication to perform a shunt embolization.However,in particular cases with many shunts and severe HE,we found that one of these shunts can be safely embolized and this procedure can be sufficient to obtain a good HE recovery.In conclusion,we reported a case of persistent HE due to a wide portosystemic shunt associated with portal vein thrombosis.As the patient had other shunts,she was successfully treated by embolization of the larger shunt. | Letícia de Campos Franzoni Fábio Cardoso de Carvalho Rafael Gomes de Almeida Garzon Fábio da Silva Yamashiro Laís Augusti Lívia Alves Amaral Santos Mariana de Souza Dorna Júlio Pinheiro Baima Talles Bazeia Lima Carlos Antonio Caramori Giovanni Faria Silva Fernando Gomes Romeiro | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 2 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 3 | Slurry sampling for the determination of mercury in rice using cold vapor atomic absorption spectrometry显示文摘 | Silva L O B da Silva D G Leao D J | 2012 | Food Analytical Methods2012，5，6： | 1 |
| 4 | Parametric Study of Adhesive Joints with Composites 显示文摘 | NETO J A B P CAMPILHO R D S G DA SILVA L F M | 2012 | International Journal of Adhesion and Adhesives2012，，： | 1 |
| 5 | Analytical models of adhesively bonded joints-Part I:literature survey显示文摘 | da Silva L F M das Neves P J C Adams R D | 2009 | International Journal of Adhesion and Adhesives2009，29，3： | 1 |
| 6 | Comprehensive two-dimensional gas chromatography/mass spectrometric analysis of pepper voatiles显示文摘 | Cardeal Z L Gomes da Silva M D Marriott P J | 2006 | Rapid Commun Mass Spectrom2006，20，： | 1 |
| 7 | An oscillometric detector for capillary electrophoresis显示文摘 | Fracassi da Silva J A do Lago C L | 1998 | Anal Chem1998，70，20： | 1 |
| 8 | Photochemical and photocatalytie degradation of an azo dye in aqueous solution by UV irradiation显示文摘 | Da Silva CG FARIA J L | 2003 | J Photoeh Photobio A2003，155，13： | 1 |
| 9 | Primary pulmonary paraganglioma:case report andliterature review显示文摘 | da Silva R A Gross J L Haddad F J | | 0，，： | 1 |
| 10 | Online voltage stability monitoring显示文摘 | DE SOU ZA A C Z DE SOUZA J C S DA SILVA A M L | 2000 | IEEE Trans on Power Systems2000，15，4： | 1 |
| 11 | A simple solid injection device for the analyses of Bulbophyllum (Orchidaceae) volatiles 显示文摘 | da Silva U F Borba E L Semir J Marsaioli A J | 1999 | Phytochemistry1999，50，： | 1 |
| 12 | PicoRadio supports ad hoc ultra-low power wireless networking 显示文摘 | Rabaey J M Ammer M J da Silva J L Jr | 2000 | Computer2000，33，7： | 1 |
| 13 | Small strain viscoelastic behaviour of wheat gluten-pentosan mixtures 显示文摘 | Santos D M J Monteiro S R Da Silva J A L | 2005 | Eur Food Res Technol2005，，221： | 1 |
| 14 | Ox-ovanadium complexes in catalytic oxidations 显示文摘 | Silva J A L da Silva J J R F da Pombeiro A J L | 2011 | Coordi-nation Chemistry Reviews2011，255，： | 1 |
| 15 | Quantitative measurement of heine oxygenase-1 in the human renal adenocarcinoma显示文摘 | GOODMAN A I CHOUDHURY M DA SILVA J L | 1996 | J Cell Biochem1996，63，3： | 1 |
| 16 | Possible generation sites of internal solitary waves observed by ERS SAR in the central region of the bay of Biscay显示文摘 | Azevedo A da Silva J C B New A L | 2002 | Ieee International Geoscience and Remote Sensing Symposium and 24th Canadian Symposium on Remote Sensing2002，，： | 1 |
| 17 | A systems ap- proach for the estimation of the effects of land consolidation project (LCPs): a model and its application 显示文摘 | Castro Colho J Aguiar Pinto P Mira da Silva L | 2001 | Agricultural System2001，68，： | 1 |
| 18 | Storage temperature effect on histamine formation in big eye tuna and skipjack显示文摘 | SILVA C C G da PONTE D J B DAPKEVICIUS M L N | 1998 | Journal of Food Science1998，63，4： | 1 |
| 19 | On the observability of internal tidal waves in remotely-sensed ocean colour data显示文摘 | da Silva J C B New A L Srokosz M A | 2002 | Geophysical Research Letters2002，29，12： | 1 |
| 20 | An Oscillometric Detector for Capillary Electrophoresis 显示文摘 | da Silva J A F do Lago C L | 1998 | Anal Chem1998，70，： | 1 |
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