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| 1 | Perfluorocarbon in vitreoretinal surgery and preoperative bevacizumab in diabetic tractional retinal detachment显示文摘AIM: To describe the en bloc perfluorodissection(EBPD) technique and to demonstrate the applicabilityof using preoperative intravitreal bevacizumab duringsmall-gauge vitreoretinal surgery(23-gauge transconjunctival sutureless vitrectomy) in eyes with advancedproliferative diabetic retinopathy(PDR) with tractionalretinal detachment(TRD).METHODS: This is a prospective, interventional caseseries. Participants included 114(eyes) with advancedproliferative diabetic retinopathy and TRD. EBPD wasperformed in 114 eyes(consecutive patients) during23-gauge vitrectomy with the utilization of preoperativebevacizumab(1.25 mg/-0.05 mL). Patients mean age was 45 years(range, 21-85 years). Surgical time had a mean of 55 min(Range, 25-85 min). Mean follow up of this group of patients was 24 mo(range, 12-32 mo). Main outcome measures included best-corrected visual acuity(BCVA), retinal reattachment, and complications.RESULTS: Anatomic success occurred in 100%(114/-114) of eyes. Significant visual improvement [≥ 2 Early Treatment Diabetic Retinopathy Study(ETDRS) lines] was obtained in 69.2%(79/-114), in 26 eyes(22.8%) BCVA remained stable, and in 8 eyes(7%) BCVA decreased(≥ 2 ETDRS lines). Final BCVA was 20/-50 or better in 24% of eyes, between 20/-60 and 20/-400 in 46% of eyes, and worse than 20/-400 in 30% of eyes. Complications included cataract in 32(28%) eyes, iatrogenic retinal breaks in 9(7.8%) eyes, vitreous hemorrhage requiring another procedure in 7(6.1%) eyes, and phthisis bulbi in 1(0.9%) eye.CONCLUSION: This study demonstrates the usefulne-ss of using preoperative intravitreal bevacizumab and EBPD during smallgauge vitreoretinal surgery in eyes with TRD in PDR. | J Fernando Arevalo Martin A Serrano Juan D Arias | 2014 | World Journal of Diabetes2014，5，5： | 3 |
| 2 | A new regulatory motif in cell cycle control causing specific inhibition of cyclinD/CDK4显示文摘 | Serrano M Hannon Gj Beach D | | 0，，： | 2 |
| 3 | A new regulatory motif in cell-cycle control causing specific inhibition of cyclinD/CDK4显示文摘 | Serrano M Hannon GT Beach D | 1993 | Nature1993，366，6： | 1 |
| 4 | The role of polyamines in the improvement of shelf life of fruits 显示文摘 | Valero D Martinez-romero D Serrano M | 2002 | Trends Food Sci Teehnol2002，13，： | 1 |
| 5 | In vivo antioxidant treatment protects against bleomycin - induced lung damage in rats 显示文摘 | A Serrano - Mollar D Closa | 2003 | British Joumal of Pharmacology2003，138，： | 1 |
| 6 | A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 显示文摘 | SERRANO M HANNON G J BEACH D | 2003 | Nature2003，366，6456： | 1 |
| 7 | The use of natural antifungal compounds improves the beneficial effect of MAP in sweet cherry storage显示文摘 | Serrano M Martínez-Romero D Castillo S | 2005 | Innovative Food Science & Emerging Technologies2005，6，1： | 1 |
| 8 | The role of polyamines in the improvement of shelf life of fruits显示文摘 | Valero D Martnez-Romero D Serrano M | 2002 | Trends Food Science Technology2002，，13： | 1 |
| 9 | Nanocrystalline ZSM-5:A catalyst with high activity and selectivity for epoxide rearrangement reactions显示文摘 | SERRANO D P VAN GRIEKEN R MELERO J A | 2010 | Journal of Molecular Catalysis A:Chemical2010，318，12： | 1 |
| 10 | Pea protein as a substi- tute of soya bean protein in diets for young pigs:Effects on productivity and digestive traits显示文摘 | Valencia D G Serrano M P Centeno C L | 2008 | Livestock Science2008，118，： | 1 |
| 11 | Tourism and Environment in Brazil 显示文摘 | Luchiari D P C^lia Serrano | 2008 | Tourism Geographies2008，3，2： | 1 |
| 12 | Beneficial effects of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta显示文摘 | Serrano M A Brites D Larena M G | 1998 | J Hepatol1998，28，： | 1 |
| 13 | Restless legs syn drome and PD:a review of the evidence for a possible associa-ion显示文摘 | Garcia Borreguero D Odin P Serrano C | 2003 | Neurology2003，61，： | 1 |
| 14 | Reduction of pomegranate chilling injury during storage after heat treatment: Role of polyamines显示文摘 | MIRDEHGHAN S H RAHEMIC M MARTINEZ-ROMERO D GUILLEN F VALVERDE J M ZAPATA P J SERRANO M VALERO D | 2007 | Postharvest Biology and Technology2007，44，： | 1 |
| 15 | Effects of exogenous putrescine on improving shelf life of four plum cultivars显示文摘 | SERRANO M MARTINEZ-ROMERO D GUILLEN F | 2003 | Postharvest Biology and Technology2003，30，： | 1 |
| 16 | The addition of essential oils to MAP as a tool to maintain the overall quality of fruits显示文摘 | SERRANO M MART NEZ-ROMERO D GUILL N F | 2008 | Trends in Food Science & Technology2008，19，9： | 1 |
| 17 | A new regulatory motif in cell -cycle control causing specific inhibition of cycle D/CDK4显示文摘 | Serrano M Hannon G J Beach D | 1993 | Nature1993，366，： | 1 |
| 18 | Beneficial effect of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta显示文摘 | Serrano MA Brites D Larena MG | 1998 | J Hepatol1998，28，5： | 1 |
| 19 | A comparative study of the disc diffusion method with the broth microdilution and Etest methods for voriconazole susceptibility testing of Aspergillus spp显示文摘 | Serrano MC Ramirez M Morilla D | 2004 | J Antimicrob Chemother2004，53，： | 1 |
| 20 | Molecular and meso-and macroscopic properties of hierarchical nanocrystalline ZSM-5 zeolite prepared by seed silanization显示文摘 | Serrano D P Aguado J Morales G | | 0，，04： | 1 |
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