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| 1 | Immunoexpression of cyclooxygenase-2 in primary gastric carcinomas and lymph node metastases显示文摘AIM: To evaluate immunoexpression of cyclooxygenase-2 (COX-2) in primary gastric carcinomas and respective lymph node metastases. METHODS: Immunohistochemistry to analyze COX-2 expression was performed on tissue microarray slices obtained from 36 specimens of gastrectomy and satellite lymph nodes from patients with gastric carcinoma. RESULTS: Immunostaining was seen in most cases, and COX-2 expression was higher in lymph node me-tastases than in corresponding primary gastric tumors of intestinal, diffuse and mixed carcinomas, with a statistically signif icant difference in the diffuse histotype (P = 0.0108). CONCLUSION: COX-2 immunoexpression occurs frequently in primary gastric carcinomas, but higher expression of this enzyme is observed in lymph node metastases of the diffuse histotype. | Paulo RC Almeida Francisco VA Ferreira Cássio C Santos Francisco D Rocha-Filho Raul RP Feitosa Esther AA Falco Belise K Cavada Roberto CP Lima-Júnior Ronaldo A Ribeiro | 2012 | World Journal of Gastroenterology2012，18，8： | 14 |
| 2 | Clinical hematological and biochemical parameters in Swiss,BALB/c,C57BL/6 and B6D2F1 Mus musculus显示文摘Background:Animal models are widely used in scientific research in order to obtain information from a whole organism under a specific set of experimental conditions.Various lineages of mice have been used to investigate diseases and new therapeutic strategies,and,consequently,hematological and biochemical tests in these laboratory animals are essential to validate scientific studies.Our study seeks to establish reference values for hematological and biochemical parameters of four lineages of mice.Methods:We evaluated the hematological and biochemical profiles of 20 males and 20 females from the lineages Swiss(heterogeneous),BALB/c and C57BL/6(isogenic),and B6D2F1(hybrid),totaling 160 mice.Analysis were standardized using the systems pocH-100iV Diff™for 19 hematological parameters and VITROS®350 for 12 biochemical parameters.Results:Results are shown as means and standard deviation,grouped by lineage and genre.Comparing the values obtained in this study with the values from previous studies,some variations were detected,which could be explained by differences in methodologies or individual variability.Conclusion:Thus our study shows that knowledge and disclosure of the values of physiological parameters of laboratory animals is necessary,and emphasises the importance of considering variations influenced by gender,lineage and genotype in the choice of the best experimental model. | Giorgio Silva-Santana Juliet Cunha Bax Débora Cristina Silva Fernandes Daniela Tendler Leibel Bacellar Cleber Hooper Alexandre Alves Souza Oliveira Dias Cristina Barbosa Silva Aline Moreira de Souza Simone Ramos Ricardo Alexandre Santos Thainara Ramos Pinto Mariana Antunes Ramão Ana Luíza Mattos-Guaraldi | 2020 | Animal Models and Experimental Medicine2020，3，4： | 2 |
| 3 | The compensatory growth response of the Anlantic cod : effects of nutritional history 显示文摘 | Jobling M Meloy O H santos J D | 1994 | Aquaculture International1994，2，： | 1 |
| 4 | Agro- industrial residues as low-price feedstock for diesel- like fuel production by thermal cracking显示文摘 | Santos A L F Martins D U Iha O K | 2010 | Bioresource Technology2010，101，： | 1 |
| 5 | The compensatory growth response of the Atlantic cod:effects of nutritional history显示文摘 | Jobing M Meloy O H Santos J D | 1994 | Aquaculture International1994，，2： | 1 |
| 6 | Psoriatic arthritis: a clinical entity distinct from psoriasis? 显示文摘 | Ruiz D G Azevedo M N Santos O L | 2012 | Rev Bras Reumatol2012，52，4： | 1 |
| 7 | A GATA - 1 - regulated microRNA locus essential for erythropoiesis 显示文摘 | Dore L C Amigo J D Dos Santos C O | 2008 | Proc Natl Acad Sci USA2008，105，9： | 1 |
| 8 | A real-time visualization tool for forest eccsystem management decision support显示文摘 | Falcao A O Santos M P D Borges J G | 2006 | Computers and Electronics in Agriculture2006，53，： | 1 |
| 9 | Auto- matic detection of small lung nodules in 3D CT data using Gaussian mixture models, Tsallis entropy and SVM 显示文摘 | SANTOS A M FILHO A O D C SILVA A C | 2014 | Engineering applications of artificial intelligence2014，，36： | 1 |
| 10 | Effects of fatty acids on liver regeneration in rats 显示文摘 | Melo J U Santos J M Kimura O D | 2010 | Rev Col Bras Cir2010，37，5： | 1 |
| 11 | Microstructural evolution at the initial stages of continuous annealing of cold rolled dual-phase steel显示文摘 | Rocha R O Melo T M F Pereloma E V Santos D B | 2005 | Materials Science and Engineering A2005，391，： | 1 |
| 12 | Agro-industrial residues as low-price feedstock for diesel-like fuel production by thermal cracking显示文摘 | Santos A L Martins D U Iha O K | | 0，，： | 1 |
| 13 | Conserved 5S and variable 45S rDNA chromosomal localisation revealed by FISH in Astyanax scabripinnis (Pisces, Characidae) 显示文摘 | MANTOVANI MONIQUEDOS SANTOS A LUCIANO D FILHO O | 2005 | Genetica2005，123，3： | 1 |
| 14 | Microstructural evolution at the initial stages of continuous annealing of cold rolled dual-phase steel 显示文摘 | Rocha R O Melo T M F Pereloma E V Santos D B | 2005 | Materials Science and Engineering2005，391，： | 1 |
| 15 | Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group(RCWG)显示文摘 | Matthijnssens J Ciarlet M McDonald S M Attoui H Banyai K Brister J R Buesa J Esona M D Estes M K Gentsch J R Iturriza-Gomara M Johne R Kirkwood C D Martella V Mertens P P Nakagomi O Parre ? o V Rahman M Ruggeri F M Saif L J Santos N Steyer A Taniguchi K Patton J T Desselherger U Van Ranst M | 2011 | Arch Virol2011，156，8： | 1 |
| 16 | Kinetic and activation ther- modynamic parameters on thermal decomposition of synthetic lubricant oils显示文摘 | SANTOS J C O OLIVEIRA A D SILVA C C | 2007 | J Therm Anal Calorim2007，87，3： | 1 |
| 17 | Translation and cross-cultural adaptation of the Brazilian Portuguese version of the driving anger scale (DAS) : long form and short form显示文摘 | CANTINI J A SANTOS G O MACHADO E D C et at | 2015 | Trends Psychiatry Psychother2015，37，： | 1 |
| 18 | The compensatory growth rezponse of the Atlantic cod: effects of nutritional history显示文摘 | Jobing M Meloy O H Santo J D | 1994 | Aquac Intern1994，，2： | 1 |
| 19 | Transcranial Doppler sonography in fulminant hepatic failure显示文摘 | A Abdo O López A Fernández J Santos J Castillo R Castellanos L González F Gómez D Limonta | 2003 | Transplantation Proceedings2003，，5： | 1 |
| 20 | The compensatory growth response of the Atlantic cod: effects of nutritional history显示文摘 | Jobling M Meloy O H Santos D J | 1994 | Aquaculture International1994，12，： | 1 |
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