|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Meta-analysis of subtotal stomach-preserving pancreaticoduodenectomy vs pylorus preserving pancreaticoduodenectomy显示文摘AIM: To investigate the differences in outcome following pylorus preserving pancreaticoduodenectomy(PPPD) and subtotal stomach-preserving pancreaticoduodenectomy(SSPPD).METHODS: Major databases including Pub Med(Medline), EMBASE and Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials(CENTRAL) in The Cochrane Library were searched for comparative studies between patients with PPPD and SSPPD published between January 1978 and July 2014. Studies were selected based on specific inclusion and exclusion criteria. The primary outcome was delayed gastric emptying(DGE). Secondary outcomes included operation time, intraoperative blood loss, pancreatic fistula, postoperative hemorrhage, intraabdominal abscess, wound infection, time to starting liquid diet, time to starting solid diet, period of nasogastric intubation, reinsertion of nasogastric tube, mortality and hospital stay. The pooled odds ratios(OR) or weighted mean difference(WMD) with 95% confidence intervals(95%CI) were calculated using either a fixed-effects or random-effects model. RESULTS: Eight comparative studies recruiting 650 patients were analyzed, which include two RCTs, one non-randomized prospective and 5 retrospective trial designs. Patients undergoing SSPPD experienced significantly lower rates of DGE(OR = 2.75; 95%CI: 1.75-4.30, P < 0.00001) and a shorter period of nasogastric intubation(OR = 2.68; 95%CI: 0.77-4.58,P < 0.00001), with a tendency towards shorter time to liquid(WMD = 2.97, 95%CI:-0.46-7.83; P = 0.09) and solid diets(WMD = 3.69, 95%CI:-0.46-7.83; P = 0.08) as well as shorter inpatient stay(WMD = 3.92, 95%CI:-0.37-8.22; P = 0.07), although these latter three did not reach statistical significance. PPPD, however, was associated with less intraoperative blood loss than SSPPD [WMD =-217.70, 95%CI:-429.77-(-5.63); P = 0.04]. There were no differences in other parameters between the two approaches, including operative time(WMD =-5.30, 95%CI:-43.44-32.84; P = 0.79), pancreatic fistula(OR = 0.91; 95%CI: 0.56-1.49; P = 0.70), postoperative hemorrhage(OR = 0.51; 95%CI: 0.15-1.74; P = 0.29), intraabdominal abscess(OR = 1.05; 95%CI: 0.54-2.05; P = 0.89), wound infection(OR = 0.88; 95%CI: 0.39-1.97; P = 0.75), reinsertion of nasogastric tube(OR = 1.90; 95%CI: 0.91-3.97; P = 0.09) and mortality(OR = 0.31; 95%CI: 0.05-2.01; P = 0.22).CONCLUSION: SSPPD may improve intraoperative and short-term postoperative outcomes compared to PPPD, especially DGE. However, these findings need to be further ascertained by well-designed randomized controlled trials. | Wei Huang Jun-Jie Xiong Mei-Hua Wan Peter Szatmary Shameena Bharucha Ilias Gomatos Quentin M Nunes Qing Xia Robert Sutton Xu-Bao Liu | 2015 | World Journal of Gastroenterology2015，21，20： | 8 |
| 2 | Prophylactic intra-peritoneal drain placement following pancreaticoduodenectomy:A systematic review and metaanalysis显示文摘AIM:To conduct a meta-analysis comparing outcomes after pancreaticoduodenectomy(PD)with or without prophylactic drainage.METHODS:Relevant comparative randomized and nonrandomized studies were systemically searched based on specific inclusion and exclusion criteria.Postoperative outcomes were compared between patients with and those without routine drainage.Pooled odds ratios(OR)with 95%CI were calculated using either fixed effects or random effects models.RESULTS:One randomized controlled trial and four non-randomized comparative studies recruiting 1728patients were analyzed.Patients without prophylactic drainage after PD had significantly higher mortality(OR=2.32,95%CI:1.11-4.85;P=0.02),despite the fact that they were associated with fewer overall complications(OR=0.62,95%CI:0.48-0.82;P=0.00),major complications(OR=0.75,95%CI:0.60-0.93;P=0.01)and readmissions(OR=0.77,95%CI:0.60-0.98;P=0.04).There were no significant differences in the rates of pancreatic fistula,intraabdominal abscesses,postpancreatectomy hemorrhage,biliary fistula,delayed gastric emptying,reoperation or radiologic-guided drains between the two groups.CONCLUSION:Indiscriminate abandonment of intraabdominal drainage following PD is associated with greater mortality,but lower complication rates.Future randomized trials should compare routine vs selective drainage. | Yi-Chao Wang Peter Szatmary Jing-Qiang Zhu Jun-Jie Xiong Wei Huang Ilias Gomatos Quentin M Nunes Robert Sutton Xu-Bao Liu | 2015 | World Journal of Gastroenterology2015，21，8： | 7 |
| 3 | It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis显示文摘Background There is concern that blood pressure(BP)lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis.We assessed the effect of glyceryl trinitrate(GTN)in patients with carotid stenosis using data from the Efficacy of Nitric Oxide in Stroke(ENOS)Trial.Methods ENOS randomised 4011 patients with acute stroke and raised systolic BP(140-220 mm Hg)to transdermal GTN or no GTN within 48 hours of onset.Those on prestroke antihypertensives were also randomised to stop or continue their medication for 7 days.The primary outcome was the modified Rankin Scale(mRS)at day 90.Ipsilateral carotid stenosis was split:<30%;30-<50%;50-<70%;≥70%.Data are ORs with 95%CIs adjusted for baseline prognostic factors.results 2023(60.5%)ischaemic stroke participants had carotid imaging.As compared with<30%,≥70%ipsilateral stenosis was associated with an unfavourable shift in mRS(worse outcome)at 90 days(OR 1.88,95%CI 1.44 to 2.44,p<0.001).Those with≥70%stenosis who received GTN versus no GTN had a favourable shift in mRS(OR 0.56,95%CI 0.34 to 0.93,p=0.024).In those with 50-<70%stenosis,continuing versus stopping prestroke antihypertensives was associated with worse disability,mood,quality of life and cognition at 90 days.Clinical outcomes did not differ across bilateral stenosis groups.Conclusions Following ischaemic stroke,severe ipsilateral carotid stenosis is associated with worse functional outcome at 90 days.GTN appears safe in ipsilateral or bilateral carotid stenosis,and might improve outcome in severe ipsilateral carotid stenosis. | Jason P Appleton Lisa J Woodhouse Andrew Belcher Daniel Bereczki Eivind Berge Valeria Caso Hui Meng Chang Hanne K Christensen Ronan Collins John Gommans Ann C Laska George Ntaios Serefnur Ozturk Gillian M Sare Szabolcs Szatmari Yongjun Wang Joanna M Wardlaw Nikola Sprigg Philip M Bath for the ENOS investigators | 2019 | Stroke & Vascular Neurology2019，4，1： | 6 |
| 4 | Role of kinase suppressor of Ras - 1 in neuronal survival signaling by ext racellular signal - regulated kinase 1/2 显示文摘 | Szatmari E Kalita KB Kharebava G | 2007 | Neurosci2007，27，11： | 1 |
| 5 | Activation of CaMKII in single dendritic spines during long-term potentiation 显示文摘 | LEE S J ESCOBEDO-LOZOYA Y SZATMARI E M | 2009 | Nature2009，458，7236： | 1 |
| 6 | Mapping autism risk loci using genetic linkage and chromosomal rearrangements 显示文摘 | Autism Genome Project Consortium Szatmari P Paterson A D | 2007 | Nature Gene2007，39，3： | 1 |
| 7 | Meta-analysis of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy显示文摘 | Xiong J J Tan C L Szatmary P | 2014 | Br J Surg2014，101，10： | 1 |
| 8 | High-per- formance liquid chromatographic enantioseparation of 1-(aminoalkyl)-2-naphthol analogs on polysaccharide-based chiral stationary phases 显示文摘 | Sztojkov-Ivanov A Toth D Szatmari I | 2007 | Chirality2007，19，5： | 1 |
| 9 | Petroleum formation by Fischer-Tropsch synthesis in plate tectonics显示文摘 | Szatmari P | 1989 | AAPG Bull1989，73，8： | 1 |
| 10 | Sodium Titanate Nanorods:Preparation,Microstructure Characterization and Photocatalytic Activity显示文摘 | (S)tengl V Bakardjieva S ubrt J Vecerníková E Szatmary L Klementová M Balek V | 2006 | Applied Catalysis B:Environmental2006，63，： | 1 |
| 11 | C-23 hydroxylation by Axabidopsis CYP90C1 and cYPg0D1 reveals a novel shortcut in brassinos- teroid biosynthesis显示文摘 | Ohnishi T Szatmari A M Watanabe B | 2006 | The Plant Cell Online2006，18，11： | 1 |
| 12 | Subcortical features and cogni- tive performance in Hungarian cerebrovascular outpatients 显示文摘 | Szatmari S Csiba L Fekete I | 2002 | Neu- rol Sci2002，，203204： | 1 |
| 13 | Motor coordination and emotional-behavioral problems in children显示文摘 | Cairney J Veldhuizen S Szatmari P | 2010 | Curr Opin Psychiatry2010，23，4： | 1 |
| 14 | The prevalence of anxiety and mood problems among children with autism and Asperger syndrome显示文摘 | Kim JA Szatmari P Bryson SE | 2000 | Autism2000，4，2： | 1 |
| 15 | Molecular biology of toll-like receptors 显示文摘 | Szatmary Z | 2012 | Gen Physiol Biophys2012，31，4： | 1 |
| 16 | Molecular biology of toll-like receptors 显示文摘 | Szatmary Z | 2012 | Gen Physiol Biophys2012，31，4： | 1 |
| 17 | Generation of input signals for ArF Amplifers显示文摘 | S Szatmari F P Schafer | 1989 | Opt Soc Am B1989，6，10： | 1 |
| 18 | Antecedents and sex/gender differences in youth suicidal behavior显示文摘Suicide is the second leading cause of death in youth globally; however, there is uncertainty about how best to intervene. Suicide rates are typically higher in males than females, while the converse is true for suicide attempts. We review this 'gender paradox' in youth, and in particular, the age-dependency of these sex/gender differences and the developmental mechanisms that may explain them. Epidemiologic, genetic,neurodevelopmental and psychopathological research have identified suicidal behaviour risks arising from genetic vulnerabilities and sex/gender differences in early adverse environments, neurodevelopment, mental disorder and their complex interconnections. Further, evolving sex-/gender-defined social expectations and norms have been thought to influence suicide risk. In particular, how youth perceive and cope with threats and losses(including conforming to others' or one's own expectations of sex/gender identity) and adapt to pain(through substance use and helpseeking behaviours). Taken together, considering brain plasticity over the lifespan, these proposed antecedents to youth suicide highlight the importance of interventions that alter early environment(s)(e.g., childhood maltreatment) and/or one's ability to adapt to them. Further, such interventions may have more enduring protective effects, for the individual and for future generations, if implemented in youth. | Anne E Rhodes Michael H Boyle Jeffrey A Bridge Mark Sinyor Paul S Links Lil Tonmyr Robin Skinner Jennifer M Bethell Corine Carlisle Sarah Goodday Travis Salway Hottes Amanda Newton Kathryn Bennett Purnima Sundar Amy H Cheung Peter Szatmari | 2014 | World Journal of Psychiatry2014，4，4： | 1 |
| 19 | Effects of different tidal volumes for one -lung ventilation on oxygenation with open chest condition and surgical manipulation: a randomised cross -over trial 显示文摘 | Vegh T Juhasz M Szatmari S | 2013 | Minerva Anestesiol2013，79，1： | 1 |
| 20 | A Prospective Case Series of High-risk Infants who Developed Autism显示文摘 | Susan E. Bryson Lonnie Zwaigenbaum Jessica Brian Wendy Roberts Peter Szatmari Vicki Rombough Catherine McDermott | 2007 | Journal of Autism and Developmental Disorders2007，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员