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| 1 | Fundamentals of case study research in family medicine and community health显示文摘The aim of this article is to introduce family medicine researchers to case study research,a rigorous research methodology commonly used in the social and health sciences and only distantly related to clinical case reports.The article begins with an overview of case study in the social and health sciences,including its definition,potential applications,historical background and core features.This is followed by a 10-step description of the process of conducting a case study project illustrated using a case study conducted about a teaching programme executed to teach international family medicine resident learners sensitive examination skills.Steps for conducting a case study include(1)conducting a literature review;(2)formulating the research questions;(3)ensuring that a case study is appropriate;(4)determining the type of case study design;(5)defining boundaries of the case(s)and selecting the case(s);(6)preparing for data collection;(7)collecting and organising the data;(8)analysing the data;(9)writing the case study report;and(10)appraising the quality.Case study research is a highly flexible and powerful research tool available to family medicine researchers for a variety of applications. | Sergi Fàbregues Michael D Fetters | 2019 | Family Medicine and Community Health2019，7，2： | 8 |
| 2 | Adsorption of Phenylalanine onto Polymeric Resins: Equilibrium, Kinetics and Operation of a Parametric Pumping Unit 显示文摘 | Sergi D Anabela L Licinio F etal | 1998 | Separation and Purification Technology1998，13，： | 1 |
| 3 | Nceadjuvant endocrine therapy for locally advanced breast cancer显示文摘 | Viola G Sergi D Conti F | 2007 | Clin Ter2007，158，5： | 1 |
| 4 | Lack of intra-aortie balloon pump ef- fiectiveness in high-risk percutaneous coronary interventions without cardiogenic shock: a comprehensive meta-analysis of randomised trials and obsmwational studies 显示文摘 | Romeo F Aeconcia MC Sergi D | 2013 | lnt J Cardiol2013，167，5： | 1 |
| 5 | Mechanism of action of and resistance to quinolones显示文摘 | Anna F Sergi M Ernest G | 2009 | Microb Biotechnol2009，2，3： | 1 |
| 6 | Cross-layer design for double-string cooperative communications in wireless ad- hoc networks显示文摘 | Sergi S Pancaldi F Vitetta G M | 2011 | European Transactions on Telecommu- nications2011，22，8： | 1 |
| 7 | Modeling of a range extender power train for a city bus显示文摘 | Dispenza G Andaloro G Sergi F | 2012 | ECS Transactions2012，42，1： | 1 |
| 8 | Molecular mechanisms and thera- peutical implications of Intramembrane Receptor/Receptor Interaetions among Heptahelieal Receptors with Examples from the Striatopallidal GABA Neurons显示文摘 | Luigi FA Sergi F Carme L | 2003 | Pharmaeol Rev2003，55，： | 1 |
| 9 | Lack of intra-aortic balloon pump effectiveness in high-risk percutaneous coronary interventions without cardio- genic shock: A comprehensive meta-analysis of ran- domised trials and observational studies显示文摘 | ROMEO F ACCONCIA M C SERGI D | 2013 | Int J Car- diol2013，，： | 1 |
| 10 | The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization: A comprehensive meta-analysis显示文摘 | ROMEO F ACCONCIA MC SERGI D | 2013 | Am Heart J2013，165，： | 1 |
| 11 | Adenosine A1-A2A recep- tor heteromers: new targets for caffeine in the brain显示文摘 | Sergi F Francisco C Janusz B | 2008 | Front Biosci2008，1，13： | 1 |
| 12 | Anti-cancer PEG-enzymes:30 years old,but still a current approach显示文摘 | Pasut G Sergi M Veronese F M | 2008 | Adv Drug Delivery Rev2008，60，1： | 1 |
| 13 | Abscisic Acid Connects Phytohormone Signaling with RNA Metabolic Pathways and Promotes an Antiviral Response that Is Evaded by a Self- Controlled RNA Virus显示文摘A complex network of cellular receptors,RNA targeting pathways,and small-molecule signaling provides robust plant immunity and tolerance to viruses.To maximize their fitness,viruses must evolve control mechanisms to balance host immune evasion and plant-damaging effects.The genus Potyvirus comprises plant viruses characterized by RNA genomes that encode large polyproteins led by the P1 protease.A P1 autoinhibitory domain controls polyprotein processing,the release of a downstream functional RNAsilencing suppressor,and viral replication.Here,we show that P1Pro,a plum pox virus clone that lacks the P1 autoinhibitory domain,triggers complex reprogramming of the host transcriptome and high levels of abscisic acid(ABA)accumulation.A meta-analysis highlighted ABA connections with host pathways known to control RNA stability,turnover,maturation,and translation.Transcriptomic changes triggered by P1Pro infection or ABA showed similarities in host RNA abundance and diversity.Genetic and hormone treatment assays showed that ABA promotes plant resistance to potyviral infection.Finally,quantitative mathematical modeling of viral replication in the presence of defense pathways supported self-control of polyprotein processing kinetics as a viral mechanism that attenuates the magnitude of the host antiviral response.Overall,our findings indicate that ABA is an active player in plant antiviral immunity,which is nonetheless evaded by a self-controlled RNA virus. | Fabio Pasin Hongying Shan Beatriz García Maren Müller David San León Márta Ludman David H.Fresno Károly Fátyol Sergi Munné-Bosch Guillermo Rodrigo Juan Antonio García | 2020 | Plant Communications2020，1，5： | 1 |
| 14 | Double actuationarchitectures for rendering variable impedance in compliantrobots: A review 显示文摘 | Tagliamonte N L Sergi F Accoto D | 2012 | Mechatronics2012，22，8： | 1 |
| 15 | Collagen changes in the ureteropelvic junction after failed antegrade endopyelotomy显示文摘 | Sergi F Flammia GP Alcini A | 2007 | J Endourol2007，21，1： | 1 |
| 16 | Molecular char- acterization of acinetobacter isolates collected in intensive care units of six hospitals in Florence, Italy, during a 3 - year surveillance program: a population structure analysis显示文摘 | DONNARUMMA F SERGI S INDORATO C | 2010 | J Chn Microbiol2010，48，4： | 1 |
| 17 | Collagen changes in the ureteropelvic junction after failed antegrade endopyelotomy显示文摘 | Sergi F Flammia GP Alcini A | 2007 | J Endourol2007，21，1： | 1 |
| 18 | The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization: A comprehensive recta-analysis显示文摘 | Romeo F Acconcia MC Sergi D | 2013 | Am Heart J2013，165，5： | 1 |
| 19 | Robotic - assisted laparoscopic sim- ple prostatectomy and bladder diverticulectomy with temporary clamping of internal iliac arteries 显示文摘 | Sergi F Falavolti C Bove AM | 2014 | Journal of Robotic Surgery2014，8，1： | 1 |
| 20 | On topological entropy of triangular maps of the square显示文摘 | LLUíS ALSEDà SERGI i F KOLYADA LUBOMíR SNOHA | 1993 | Bull Austral Math Soc1993，48，： | 1 |
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