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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | Effect of dietary supplementation with either conjugated linoleic acid(CLA)or linoleic acid rich oil on the CLA content of lamb tissues显示文摘 | Mir Z Rushfeldt M L Mir P S | 2000 | Small Rum Res2000，36，： | 1 |
| 3 | Atorvastatin improves left vetricular systolil function and serum markers of inflammation in nonischemic heart failure显示文摘 | Sola S Mir MQ Lerakis S | 2006 | J Am Coll Cardiol2006，47，2： | 1 |
| 4 | PI- Fuzzy estimations for Tuning the Stator Resistance in DTC显示文摘 | Sayeed Mir Malik E Elbuluk Donald S Zinger | 1998 | IEEE trans on PE1998，13，2： | 1 |
| 5 | PI-Fuzzy Estimations Tuning the Stator Resistance in DTC显示文摘 | Sayeed Mir Malik E Elbuluk Donald S Zinger | 1998 | IEEE Trans on Power Electrics1998，13，2： | 1 |
| 6 | Plasma concentrations of N-Terminal pro-brain natriuretic peptide in control children from the neonatal to adolescent period and in children with congestive heart failure显示文摘 | Mir TS Marohn S Laer S | 2002 | Pediatrics2002，110，6： | 1 |
| 7 | Plasma concentrations of N-terminal pro-brain natriuretic peptide in control children from the neonatal to adolescent period and in children with congestive heart failure显示文摘 | MIR T S MAROHN S LAER S | 2002 | Pediatrics2002，110，6： | 1 |
| 8 | Issues in reducing the cogging torque of mass-produced permanent-magnet brushless DC motor显示文摘 | Islam M S Mir S Sebastian T | 2004 | IEEE Transactions on Industry Applications2004，40，3： | 1 |
| 9 | Changes in the etiology, incidence and prognosis of acute lower respiratory track infections in human immunodeficiency virus patients显示文摘 | Rafael Perelló Ona Escoda Silvia Camón òscar Miró Marta Casta?eda Asunción Moreno Maria ángeles Marcos Verónica Perea Natalia Alcolea Miquel Sánchez Josep Maria Gatell Esteban Martínez | 2014 | Enfermedades Infecciosas y Microbiologia Clinica2014，，： | 1 |
| 10 | PI and fuzzy estimators for tuning the stator resistance in direct torque control of induction machines显示文摘 | Elbuluk M E Zinger D S | 1998 | IEEE Trans on Power Electronics1998，13，2： | 1 |
| 11 | Clinical outcome in children with Henoch-Sch(o)nlein nephritis显示文摘 | Mir S Yavascan O Mutlubas F | 2007 | Pediatr Nephrol2007，22，1： | 1 |
| 12 | Hypercoagulability risk factors in children with minimal change disease and the protective role of pro- tein-C activity 显示文摘 | Ozkayin N Mir S Kavakli K | 2004 | Int Urel Nephrol2004，36，4： | 1 |
| 13 | Atorvastatin improves left ven- tricular systolic function and serum markers of inflammation in nonischemic heart failure显示文摘 | Sola S Mir MQ Lerakis S | 2006 | J Am CoU Cardiol2006，47，： | 1 |
| 14 | Texture analysis of CT images显示文摘 | Mir A H Hanmandlu M Tandon S N | 1995 | Engineering in Medicine and Biology Magazine1995，14，6： | 1 |
| 15 | Interleukin 8 gene 2767 A/G polymorphism is associated with increased risk of nephritis in children with Henoch-Sch? nlein purpura显示文摘 | Tabel Y Mir S Berdeli A | | 0，，： | 1 |
| 16 | FTIR studies of butane,toluene and nitric oxide adsorption on Ag exchanged NaMordenite显示文摘 | Aspromonte S G Miró E E Boix A V | 2012 | Adsorption2012，18，1： | 1 |
| 17 | PI and Fuzzy Esti- mations for Tuning the Stator Resistance in DTC of Induction Ma- chines显示文摘 | Sayeed Mir Malik E Elbuluk Donald S Zinger | 1998 | IEEE Trans on Power Electron1998，13，2： | 1 |
| 18 | A comparative histologic study of the fibrillin microfibrillar system in thelens capsule of normal subjects and subjects with marfan syndrome显示文摘 | Mir S Wheatley HM Hussels IE | 1998 | Invest Ophthalmol Vis Sci1998，39，1： | 1 |
| 19 | Plasma concentrations of N-tenninal pro-brain natriuretie peptide in control children from the neonatal to adolescent period and in children witb congestive heart failure 显示文摘 | Mir TS Marohn S Laer S | 2002 | Pediatrics2002，110，6： | 1 |
| 20 | Fuzzy controller for inverter Fed induction machines 显示文摘 | MIR S A | 1996 | Jinan: Shandong University Press1996，，： | 1 |
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