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583篇 您的检索式:作者名="Rowland R"
    题名 作者 年代 出处 被引量
1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Stimulation of apoptosis by two prebiotic chicory fructans in the rat colon 显示文摘Hughes R Rowland IR 2001Carcinogenesis2001,22,1:1
3Impact of polymer films thickness and cavity size on polymer flow during embossing: Toward proces design rules for nanoimprint lithography显示文摘ROWLAND H D SUN A C SCHUNK P R 2005Journal of Micromechanics and Microengineering2005,15,:1
4Genetic analysis of tolerance in blueberry(Vaccinium section Cyanococcus)显示文摘Arora R Rowland L J Lehmann J S 2000690-6962000,,:1
5Biodegradation of aromatic hydrocarbons in crudes oils from the Barrow Sub-basin of Western Australia显示文摘Volkman J K Alexander R Kagi R I Rowland S J Sheppard P N 1984Org Geochem1984,6,62:1
6Researchers' e-journal use and information seeking behavior显示文摘Nicholas D Williams P Rowlands I Jamali H R 2010Journal of Information Science2010,,36:1
7The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomain 显示文摘Plagemann P G Rowland R R Faaberg K S 2002Arch Virol2002,147,12:1
8The localization of porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus of infected cells and identification of a potential nucleolar localization signal sequence显示文摘Rowland RR Kervin R Kuckleburg C 1999Virus Res1999,64,1:1
9Perceived control over ejaculation is central to treatment benefit in men with premature ejaculation显示文摘Shabsigh R Patrick D L Rowland D L 2008BJU Int2008,102,7:1
10Diffusion factors 显示文摘Frandsen T F Rousseau R Rowlands I 2006Journal of Documentation2006,62,1:1
11Continuous full field representation and differentiation of three:dimensional experimental vector data显示文摘Feng Z Rowlands R E 1987Computers and Structures1987,26,6:1
12Porcine reproductive and respiratory syndrome virus:an update on an emerging and re-emerging viral disease of swine显示文摘Lunney J K Benfield D A Rowland R R 0,,:1
13Student digital information-seeking behavior in context显示文摘Nicholas D Huntington P Jamali H R Rowlands I Fieldhouse M 2009Journal of Documentation2009,65,1:1
14Tissue rupture and bubble formation during radiofrequency catheter ablation : 'Echoes of a Pop' 显示文摘Juneja R O'Callaghan P Rowland E 2001Circulation2001,103,9:1
15Induction and release of bud dormancy in woody perennials :A science comes of age显示文摘ARORA R ROWLAND L J TANINO K 2003Hort Science2003,38,:1
16Substrate complexes of hepatitis C virus RNA polymerase(HC-J4):structural evidence for nucleotide import and de-novo initiation显示文摘O'Farrell D Trowbridge R Rowlands D J(a)ger J 0,,04:1
17Control of porcine reproductive and respiratory syndrome (PRRS) through genetic improvements in disease resistance and tolerance显示文摘Rowland R R Lunney J Dekkers J 2012Front Genet2012,3,:1
18Association Be- tween Stillbirth and Illicit Drug Use and Smoking During Pregnancy 显示文摘Vamer M W Silver R M Rowland Hogue C J 2014Obstetrics & Gynecology2014,123,1:1
19Diet, fecal water, and colon cancer - development of a biomarker 显示文摘PEARSON J R GILL C I R ROWLAND I R 2009Nutr Rev2009,67,9:1
20Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine显示文摘Rowland R R Robinson B Stefanick J 2001Arch Virol2001,146,3:1
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