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| 1 | Polymorphisms of DNA repair genes XRCC1 and XRCC3, interaction with environmental exposure and risk of chronic gastritis and gastric cancer显示文摘AIM: To evaluate the association between polymorphisms XRCC1 Arg194Trp and Arg399Gln and XRCC3Thr241Met and the risk for chronic gastritis and gastric cancer, in a Southeastern Brazilian population.METHODS: Genotyping by PCR-RFLP was carried out on 202 patients with chronic gastritis (CG) and 160 patients with gastric cancer (GC), matched to 202 (C1) and 150(C2) controls, respectively.RESULTS: No differences were observed among the studied grou ps with regard to the genotype distribution of XRCC1 codons 194 and 399 and of XRCC3 codon 241. However, the combined analyses of the three variant alleles (194Trp, 399Gln and 241Met) showed an increased risk for chronic gastritis when compared to the GC group. Moreover, an interaction between the polymorphic alleles and demographic and environmental factors was observed in the CG and GC groups. XRCC1 194Trp was associated with smoking in the CG group,while the variant alleles XRCC1 399Gln and XRCC3241Met were related with gender, smoking, drinking and H pylori infection in the CG and GC groups.CONCLUSION: Our results showed no evidence of a rela-tionship between the polymorphisms XRCC1Arg194Trp and Arg399Gln and XRCC3 Thr241Met and the risk of chronic gastritis and gastric cancer in the Brazilian population, but the combined effect of these variants may interact to increase the risk for chronic gastritis,considered a premalignant lesion. Our data also indicate a gene-environment interaction in the susceptibility to chronic gastritis and gastric cancer. | Márcia Cristina Duarte Jucimara Colombo Andrea Regina Baptista Rossit Alaor Caetano Aldenis Albaneze Borim Durval Wornrath Ana Elizabete Silva | 2005 | World Journal of Gastroenterology2005，11，42： | 11 |
| 2 | Measurement of resistant starch by enzymatic digestion in starch and selected plant materials: collaborative study 显示文摘 | McCleary B V MeNally M Rossiter P | 2002 | Journal of AOAC International2002，85，5： | 1 |
| 3 | Induction motor drive system for low power applications显示文摘 | C B Jacobina M B de Rossiter Correa E R C da Silva | | 0，，01： | 1 |
| 4 | Developing a minimum dataset for characterizing soil dynamics in shifting cultivation systems显示文摘 | Yemefack M Jetten V G Rossiter D G | 2006 | Soil & Tillage Research2006，86，： | 1 |
| 5 | A new electronic-topological investigation of the relationship between chemical structure and ambergris odour显示文摘 | Gorbachov M Yu Rossiter K J | 1999 | Chem Senses1999，24，： | 1 |
| 6 | Measurement of resistant starch by enzymatic digestion in starch and selected plant materials:collaborative study 显示文摘 | McCleary B V MeNally M Rossiter P | 2002 | Journal of AOAC International2002，85，5： | 1 |
| 7 | Caring in nursing:perceptions of Hong Kong nurses 显示文摘 | Bernard M C Rossiter J C | 2000 | J Clin Nurs2000，9，2： | 1 |
| 8 | The effect of vasoactive intestinal polypeptide on the lower esophageal sphincter in achalasia显示文摘 | Guelrud M Rossiter A Souney PF | 1992 | Gastroenterology1992，103，2： | 1 |
| 9 | The myrosinase glucosinolates system, its organization and biochemistry显示文摘 | BONES A M ROSSITER J T | 1996 | Plant Physiol1996，97，： | 1 |
| 10 | Factor Ⅷ gene inversions in severe hemophilia A: Results of an international consortium study显示文摘 | Antonarakis SE Rossiter JP Young M | 1995 | Blood1995，86，6： | 1 |
| 11 | Peste des Petits RuminantsAntibodies in East-Africa显示文摘 | WAWSAYI H M ROSSITER P B KARIUKI D P | 1995 | Vet Rec1995，136，8： | 1 |
| 12 | Expression of Toll - like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases 显示文摘 | Jackson AC Rossiter JP Lafon M | 2006 | J Neurovirol2006，12，3： | 1 |
| 13 | The Myrosinase - Glucosinolate System, its Organization and Biochemistry 显示文摘 | Bones A M Rossiter J T | 1996 | PHysiol Plant1996，，97： | 1 |
| 14 | Measurement of resistant starch by enzymatic digestion in starch and selected plant materials:collaborative study显示文摘 | McCleary B V McNally M Rossiter P | 2002 | Journal of AOAC International2002，85，5： | 1 |
| 15 | Maternal effects hypothesis of herbivore outbresk显示文摘 | Rossiter M C | 1994 | Bioscience1994，44，： | 1 |
| 16 | Multi-scale characterization of soil variability within an agricultural landscape mosaic system in southern Cameroon显示文摘 | Yemefaek M Rossiter D G Njomgang R | 2005 | Geoderma2005，125，： | 1 |
| 17 | Sphincter of Oddi manometry in healthy volunteers 显示文摘 | Guelrud M Mendoza S Rossiter G | 1990 | Dig Dis Sci1990，35，1： | 1 |
| 18 | Factor Ⅷ gene inversions in sever hemophilia A: results of an international consortium study 显示文摘 | Antonarakis S E Rossiter J P Young M | 1995 | Blood1995，86，6： | 1 |
| 19 | Caring in nursing: perceptions of Hong Kong nurses显示文摘 | Yam - B - M Rossiter - J - C | 2000 | J - Clin - Nurs2000，9，2： | 1 |
| 20 | Approximate studyof the free vibrations of a cantilever anisotropic plate carryinga concentrated mass显示文摘 | Ciancio P M Rossit C A Laura P A A | 2007 | Journal of Sound and Vibration2007，302，3： | 1 |
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