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1L-arginine-induced experimental pancreatitis显示文摘Despite medical treatment, the lethality of severe acute pancreatitis is still high (20-30%). Therefore, it is very important to find good animal models to characterise the events of this severe disease. In 1984, Mizunuma et. al. developed a new type of experimental necrotizing pancreatitis by intraperitoneal administration of a high dose of L-arginine in rats. This non-invasive model is highly reproducible and produces selective, dose-dependent acinar cell necrosis.Not only is this a good model to study the pathomechanisne of acute necrotizing pancreatitis, but it is also excellent to observe and influence the time course changes of the disease. By writing this review we iluminate some new aspects of cell physiology and pathology of acute necrotizing pancreatitis. Unfortunately, the reviews about acute experimental pancreatitis usually did not discuss this model.Therefore, the aim of this manuscript was to summarise the observations and address some challenges for the future in L-arginine-induced pancreatitis.PéterHegyi ZoltánRakonczayJr RékaSári CsabaGóg JánosLonovics TamásTakács LászlóCzakó 2004World Journal of Gastroenterology2004,10,14:7
2Compared efficacy of preservation solutions on the outcome of liver transplantation:Meta-analysis显示文摘AIM To compare the effects of the four most commonly used preservation solutions on the outcome of liver transplantations.METHODS A systematic literature search was performed using MEDLINE, Scopus, EMBASE and the Cochrane Library databases up to January 31^(st), 2017. The inclusion criteria were comparative, randomized controlled trials(RCTs) for deceased donor liver(DDL) allografts with adult and pediatric donors using the gold standard University of Wisconsin(UW) solution or histidinetryptophan-ketoglutarate(HTK), Celsior(CS) and Institut Georges Lopez(IGL-1) solutions. Fifteen RCTs(1830 livers) were included; the primary outcomes were primary non-function(PNF) and one-year posttransplant graft survival(OGS-1). RESULTS All trials were homogenous with respect to donor and recipient characteristics. There was no statistical difference in the incidence of PNF with the use of UW, HTK, CS and IGL-1(RR = 0.02, 95%CI: 0.01-0.03, P = 0.356). Comparing OGS-1 also failed to reveal any difference between UW, HTK, CS and IGL-1(RR = 0.80, 95%CI: 0.80-0.80, P = 0.369). Two trials demonstrated higher PNF levels for UW in comparison with the HTK group, and individual studies described higher rates of biliary complications where HTK and CS were used compared to the UW and IGL-1 solutions. However, the meta-analysis of the data did not prove a statistically significant difference: the UW, CS, HTK and IGL-1 solutions were associated with nearly equivalent outcomes.CONCLUSION Alternative solutions for UW yield the same degree of safety and effectiveness for the preservation of DDLs, but further well-designed clinical trials are warranted.Agnes Lilla Szilágyi Péter Mátrai Péter Hegyi Eszter Tuboly Daniella Pécz András Garami Margit Solymár Erika Pétervári Márta Balaskó Gábor Veres László Czopf Bastian Wobbe Dorottya Szabó Juliane Wagner Petra Hartmann 2018World Journal of Gastroenterology2018,24,16:5
3强制对流条件下不同传热流体对含相变材料柱形容器放热性能的影响显示文摘本文采用数值模拟方法研究了强制对流条件下不同传热流体对含相变材料柱形容器的放热性能的影响。以空气、氢、水和含氧化铝颗粒的纳米流体作为传热流体,同时考虑了含相变材料(PCM)区域的结构变化,采用有限元法进行求解。研究了不同传热流体类型、雷诺数(100~300)和含PCM区域结构变化(h_(x)在0.01d_(1)~0.65d_(1),h_(y)在0.1h_(1)~0.4h_(1))下不同相的换热动力学特征。研究发现,换热流体类型对放热时间影响较大,以空气为换热流体时相变完成时间比以空气为换热流体时的长10倍以上,而以纳米流体为换热流体时的时间最短。当含PCM区域减小时,放热时间缩短。含PCM区域的结构导致涡流的形成,这使在内筒的半径和高度最大处的性能下降。当内筒半径从h_(x)=0.35d_(1)增加到h_(x)=0.45d_(1)时,放热时间延长约12%。在不同雷诺数下,PCM的温度和液体组分的动态特性均受雷诺数的影响,与最小雷诺数相比,最大雷诺数下的PCM的放电时间缩短了48%左右。SELİMEFENDİGİL Fatih ŞİRİN Ceylin ÖZTOP Hakan F 2021Journal of Central South University2021,28,11:2
4Attracting foreign manufacturing: investment promotion and agglomeration 显示文摘Head C K Ries J C Swenson D L 1999Regional Science and Urban Economics1999,29,2:1
5Right ventricular overload causes the decrease in cardiac output after nitric oxide synthesis inhibition in endotoxemia显示文摘 Shapir Y Chen L 1998Crit Care Med1998,26,4:1
6Diabetic cardiomyopathy显示文摘Hambry RI Zoneraich S Shennan L 1974JAMA1974,229,13:1
7Cancer surveillance series: recent trends in childhood cancer incidence and mortality in the United States 显示文摘Linet S Ries L A Smith M A 1999J Nad Cancer Inst1999,91,12:1
8Diabetic cardimyopathy显示文摘Hamby RI loneraich S Sherman L 1974JAMA1974,229,13:1
9Pulmonary re-habilitation: Joint ACCP/ A AC VPR evidence-based clin-ical practice guidelines显示文摘Ries A L Bauldoff G S Carlin B W 2007Chest2007,131,1:1
10A pilot study to describe antidepressant presciptions dispensed to yetemns after 显示文摘Ried L D Tueth M J Jin H 2006Res Social Admpham2006,2,1:1
11Study of humic-like substances in fog and interstitial aerosol by size-exclusion chromatography and capillary electrophoresis显示文摘Z Krivácsy Gy Kiss B Varga I Galambos Zs Sárvári A Gelencsér á Molnár S Fuzzi M.C Facchini S Zappoli A Andracchio T Alsberg H.C Hansson L Persson 2000Atmospheric Environment2000,,25:1
12Delayed engraftment of 4-hydroperoxycyclophosphamide-purged autologous bone marrow after induction treatment containing mitoxantrone for acute myelogenous leukemia显示文摘 RUGO H S RIES C A 1996Bone Marrow Transplant1996,17,1:1
13Novel role of Egr-1 in nicotine-related neointimal formation显示文摘Vazquez-Padron RI Mateu D Rodriguez-Menocal L 2010Cardiovasc Res2010,88,2:1
14Enrichment of microorganisms that sequentially meta-, para--dechlorinate the residue of Aroclor 1260 in Housatonic River sediments 显示文摘Bedard D L Van Dort H M May RI 1997Environ Sci Technol1997,37,:1
15Group 3 late embryo enesis abundant proteins in desiccation tolerant seedlings of wheat 显示文摘Ried J L Walker Simmons M K 1993Plant Physiol1993,102,:1
16Attracting foreign manufacturing:investment promotion and agglomeration 显示文摘Head C K Ries J C Swenson D L 1999Regional Science and Urban Economics1999,29,:1
17显示文摘 Clèries L Morenza J L 1996Applied Surface Science1996,9698,:1
18Common chromosomal fragile site FRA16D sequence: identification of the FOR gent spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells 显示文摘Ried K Finnis M Hobson L 2000Hum Mol Genet2000,9,11:1
19Treatment of primary Sjogren's syndrome with hydroxychloroquine 显示文摘Fox RI Chan E Banton L 1988Am J Med1988,85,4:1
20Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells显示文摘Nieto-Miguel T Fonteriz RI Vay L 2007Cancer Res2007,67,10:1
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