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| 1 | Association of H.pylori infection with gastric carcinoma:a Meta analysis显示文摘AIM: To follow the principles of evidence based medicine to reach the integrated results of these studies.METHODS: Twenty-one papers of case-control studies were selected, including 11 on gastric cancer, 7 on precancerous lesion of stomach and 3 on lymphoma of stomach: Meta analysis was used to sum up the odds ratios (OR) of these studies.RESULTS: H. Pylori vsgastric cancer (intestinal and diffuse type): the odds ratio from the fixed effect model is 3.0016(95% Cl 2.4197-3.7234, P < 0.001 ). H. Pylori vs precancerous lesion of stomach: a random effect model was used to calculate the summary odds ratio and its value is 2.5635 (95% Cl: 1.8477-3.5566, P < 0.01). H. Pylori vs lymphoma of stomach: though the quantity of literature is too small to make Meta analysis, the data of these 3 studies show that lymphoma of stomach is highly associated with H. Pylori infections.CONCLUSION: Since it had been revealed that H. Pylori infection pre-exists in gastric carcinoma and precancerous lesions, the results of Meta analysis present a strong evidence to support the conclusion that H. Pylori infection is a risk factor for gastric carcinoma. | Fu-Bo Xue~1 Yong-Yong Xu~1 Yi Wan~1 Bo-Rong Pan~2 Jun Ren~2 Dai-Ming Fan~3 1 Department of Health Statistics,Department of2 Oncology3 Gastroenterology of XiJing Hospital,the Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China | 2001 | World Journal of Gastroenterology2001，7，6： | 66 |
| 2 | Geochemistry and mineralogy of the Late Permian coals from the Songzao Coalfield, Chongqing, southwestern China显示文摘Mineralogy and geochemistry of the four main workable coal seams (No.6, No.7, No.8, and No.11) of Late Permian age from the Songzao Coalfield, Chongqing, Southwest China, were examined using in- ductively coupled plasma-mass spectrometry (ICP-MS), X-ray fluorescence spectrometry (XRF), cold-vapor absorption spectrometry (CV-AAS), ion-selective electrode (ISE), scanning electron mi- croscopy equipped with an energy-dispersive X-ray spectrometer (SEM-EDX), and X-ray diffraction analysis (XRD). The results showed that the main workable No.8 Coal that accounts for about 60% of the total coal reserves in the Songzao Coalfield was not enriched in hazardous trace elements. The No.11 Coal has high concentrations of alkaline elements, Be (9.14 μg/g), Sc (12.9 μg/g), Ti (9508 μg/g), Mn (397 μg/g), Co (23.7 μg/g), Cu (108 μg/g), Zn (123 μg/g), Ga (32 μg/g), Zr (1304 μg/g), Nb (169 μg/g), Hf (32.7 μg/g), Ta (11.4 μg/g), W (24.8 μg/g), Hg (0.28 μg/g), Pb (28.1 μg/g), Th (24.1 μg/g), and rare earth elements (509.62 μg/g). The concentration of Nb and Ta in the No. 11 Coal is higher than the industrial grade, and their potential utilization should be further studied. Besides pyrite, quartz, calcite, and clay minerals, trace minerals including chalcopyrite, marcasite, siderite, albite, mixed-layer clay minerals of illite and smectite, monazite, apatite, anatase, chlorite, and gypsum were found in the No.11 Coal. It should be noted that alabandite of hydrothermal origin and anatase occurring as cement were identi- fied in coal. In addition, the clayey microbands derived from alkaline volcanic ashes were identified in the coal. The dominant compositions of these clayey microbands were mixed-layer clay minerals of illite and smectite, which were interlayered with organic bands. The modes of occurrence of alkaline volcanic ash bands indicate that the volcanic activities were characterized by the multiple eruptions, short time interval and small scale for each eruption during peat accumulation. The alkaline volcanic ashes were the dominant factors for the enrichment of alkaline elements, Nb, Ta, Zr, Hf, and rare earth elements, and the sulfide minerals are the main carriers of Ga, Cu, and Hg in the No. 11 Coal. | DAI ShiFeng1,2, ZHOU YiPing3, REN DeYi1, WANG XiBo1, 2, LI Dan1, 2 & ZHAO Lei1, 2 1 State Key Laboratory of Coal Resources and Safe Mining (China University of Mining and Technology), Beijing 100083, China 2 Department of Resources and Earth Science, China University of Mining and Technology, Beijing 100083, China 3 Kunming Research Institute of Coal Science, Kunming 650041, China | 2007 | Science China Earth Sciences2007，50，5： | 27 |
| 3 | Overexpression of P53 and its risk factors in esophageal cancer in urban areas of Xi′an显示文摘OverexpressionofP53anditsriskfactorsinesophagealcancerinurbanareasofXi′anQIAOGuiBin1,HANChengLong2,JIANGRenChao1,SUNChang?.. | QIAO GuiBin1, HAN ChengLong2, JIANG RenChao1, SUN ChangSheng3, WANG Yan3 and WANG YunJie3 | 1998 | World Journal of Gastroenterology1998，4，1： | 21 |
| 4 | Sequencing of PCR amplified HBV DNA pre-c and c regions in 2.2.15 cells and antiviral action by targeted antisense oligonucleotide directed against sequence显示文摘INTRODUCTIONManystudieshaveshownthatantisenseoligonucleotides(ASONs)canefficientlyinhibitHBVDNAreplicationandexpresioninvitro... | ZHOUG Sen 1, WEN Shou Ming 2, ZHANG Ding Feng 3, WANG Quan Li 4, WANG Seng Qi 4 and REN Hong 3 | 1998 | World Journal of Gastroenterology1998，4，5： | 16 |
| 5 | Preliminary study on the production of transgenic mice harboring hepatitis B virus X gene显示文摘INTRODUCTIONDespiteoverwhelmingepidemiologicalevidencelinkingpersistentHepatitisBVirus(HBV)infectionandthedevelopmentofhepato... | ZHU Huan Zhang 1, CHENG Guo Xiang 2, CHEN Jian Qu 2, KUANG Shu Yuan 3, CHENG Yong 2, ZHANG Xin Li 1, Ll Hou Da 2, XU Shao Fu 2, SHI Jing Quan 1, QIAN Geng Sun 3 and GU Jian Ren 3 | 1998 | World Journal of Gastroenterology1998，4，6： | 14 |
| 6 | Restudies on Body Surface of Dung Beetle and Application of Its Bionics Flexible Technique显示文摘A scanning electron microscope was used to observe the structures of the setae on the surface of a dung beetle Copris ochus, Motschulsky. There are lots of setae on the body surface, especially on the ventral part surface and lateral to the legs which are different in size, arrangement and shape. These setae have different lengths and many thorns on the whole seta. The top ends of these setae stand up without furcations which direct uprightly towards the surface of the touched soil. By the method of removing these setae, getting the insect weight before and after digging into the dung we affirm farther that the setae on the beetle body surface form the anti-stick and non-adherent gentle interface. The soil machines and components made by imitating the gentle body surface of beetles have favorable non-adherent results. | Jiurong Sun 1, Jianqiao Li 2, Hong Cheng 1, Zhendong Dai 3, Luquan Ren 2 1.College of Life Sciences, Peking University, Beijing, 100871,P.R. China 2.Key Laboratory of Terrain-Machine Bionics Engineering (Ministry of Education,China), Jilin University at Nanling Campus, Changchun, 130022,P.R.China 3.College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016,P.R.China | 2004 | Journal of Bionic Engineering2004，1，1： | 12 |
| 7 | Diet and gastric cancer:a case-control study in Fujian Province,China显示文摘NTRODUCTIONChangleandFuqingcitiesarelocatedinthesoutheasternpartofFujianProvince,Chinawithahighincidenceofgastriccancer.Howev... | YE Wei Min 1, YI Ying Nan 1, LUO Ren Xia 2, ZHOU Tian Shu 3, LIN Ru Tao 1 and CHEN Gui Dong 3 | 1998 | World Journal of Gastroenterology1998，4，6： | 12 |
| 8 | Primary scientific results of Chang'E-1 lunar mission显示文摘The strategic plan for the development of the unmanned Chinese Lunar Exploration Program is characterized by three distinct stages: 'orbiting around', 'landing on' and 'returning from' the Moon. The first Chinese lunar probe, Chang'E-1, which was successfully launched on October 24th, 2007 at Xichang Satellite Launch Center, and guided to crash on the Moon on March 1st, 2009, at 52.36°E, 1.50°S, in the north of Mare Fecunditatis, is the first step towards the 'orbiting around' stage. The Chang'E-1 mission lasted 495 days, exceeding the expected life-span by about four months. A total of 1.37 TB raw data was received from Chang'E-1. It was then processed into 4 TB scientific data products at various levels. Many scientific results have been obtained by analyzing these data, including especially the 'global lunar image from the first Chinese lunar explora- tion mission'. All scientific goals of Chang'E-1 have been achieved. It provides much useful materials for further advances of lunar sciences and planetary chemistry. Meanwhile, these results will serve as a firm basis for future Chinese lunar missions. | OUYANG ZiYuan1,2, LI ChunLai1, ZOU YongLiao1, ZHANG HongBo1, Lü Chang1, LIU JianZhong1, LIU JianJun1, ZUO Wei1, SU Yan1, WEN WeiBin1, BIAN Wei1, ZHAO BaoChang3, WANG JianYu4, YANG JianFeng3, CHANG Jin5, WANG HuanYu6, ZHANG XiaoHui7, WANG ShiJin7, WANG Min1, REN Xin1, MU LingLi1, KONG DeQing1, WANG XiaoQian1, WANG Fang1, GENG Liang1, ZHANG ZhouBin1, ZHENG Lei1, ZHU XinYing1, ZHENG YongChun1, LI JunDuo1, ZOU XiaoDuan1, XU Chun1, SHI ShuoBiao1, GAO YiFei1 & GAO GuanNan1 1 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China 2 Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China 3 Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China 4 Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China 5 Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008, China 6 Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China 7 Center for Space Science and Applied Research, Chinese Academy of Sciences, Beijing 100190, China | 2010 | Science China Earth Sciences2010，53，11： | 11 |
| 9 | Expression of the difference between the Cold(Han) and Hot(Re) natures of traditional Chinese medicines(Strobal and Rhubarb) based on the cold/hot plate differentiating assay显示文摘In this study, objective differences between the Cold (Han) and Hot (Re) nature of traditional Chinese medicines, e.g. Strobal and Rhubarb, are determined by using a cold/hot plate differentiation technology. A novel, self-designed cold/hot plate differentiating instrument, with methodological study, was used to investigate the intervention of Strobal and Rhubarb on the temperature tropism of mice. Compared with the ICR and BALB/c mice, it was found that KM mice on the cold/hot plate were more sensitive to the change of temperature, within the tolerant temperature range of 15-40 ℃ . The temperature tropism behavior of mice is influenced by treatment with Rhubarb and Strobal, as is the activity of ATPase in liver tissue. These trends are consistent with the definition of the Cold/Hot nature of Chinese medicines based on traditional Chinese medicinal theory. This study showed that the differences of the Cold/Hot nature of traditional Chinese medicines. might be objectively represented by the temperature tropism of animal by means of cold/hot differentiating assay. | ZHAO HaiPing1,2, ZHAO YanLing1, WANG JiaBo1, LI HanBing1,2, REN YongShen1,2, ZHOU CanPing1,3, YAN Dan1 & XIAO XiaoHe1· 1 China Military Institute of Chinese Materia Medica, 302 Military Hospital, Beijing 100039, China 2 Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China 3 Hunan University of Chinese Medicine, Changsha 410208, China | 2009 | Science China(Life Sciences)2009，52，12： | 10 |
| 10 | Changes in biodiversity and ecosystem function during the restoration of a tropical forest in south china显示文摘Tropical forests continue to vanish rapidly,but few long-term studies have ever examined if and how the lost forests can be restored.Based on a 45-year restoration study in south China,we found that a tropical rain forest,once completely destroyed,could not recover naturally without deliberate restoration efforts.We identified two kinds of thresholds that must be overcome with human ameliorative measures before the ecosystem was able to recover.The first threshold was imposed primarily by extreme physical conditions such as exceedingly high surface temperature and impoverished soil,while the second was characterized by a critical level of biodiversity and a landscape context that accommodates dispersal and colonization processes.Our three treatment catchments(un-restored barren land,single-species plantation,and mixed-forest stand)exhibited dramatically different changes in biodiversity and ecosystem functioning over 4 decades.The mixed forest,having the highest level of biodiversity and ecosystem functioning,possesses several major properties of tropical rain forest.These findings may have important implications for the restoration of many severely degraded or lost tropical forest ecosystems. | REN Hai,LI ZhiAn,SHEN WeiJun,YU ZuoYue,PENG ShaoLin,LIAO ChongHui,DING MingMao & WU JianGuo 1 South China Botanical Garden,Chinese Academy of Sciences,Guangzhou 510650,China 2 Institute of Ecology and Evolution,Zhongshan University,Guangzhou 510275,China 3 Guangdong Institute of Entomology,Guangzhou 510275,China 4 School of Life Sciences and Global Institute of Sustainability,Arizona State University,Tempe,AZ 85287,USA | 2007 | Science China(Life Sciences)2007，50，2： | 9 |
| 11 | Building a next generation Internet with source address validation architecture显示文摘The IP packet forwarding of current Internet is mainly destination based. In the forwarding process,the source IP address is not checked in most cases.This causes serious security,management and accounting problems. Based on the drastically increased IPv6 address space,a 'source address validation architecture'(SAVA) is proposed in this paper,which can guarantee that every packet received and forwarded holds an authenticated source IP address. The design goals of the architecture are lightweight,loose coupling,'multi-fence support' and incremental deployment. This paper discusses the design and implementation for the architecture,including inter-AS,intra-AS and local subnet. The performance and scalability of SAVA are described. This architecture is deployed into the CNGI-CERNET2 infrastructure―a large-scale native IPv6 backbone network of the China Next Generation Internet project. We believe that the SAVA will help the transition to a new,more secure and dependable Internet. | WU JianPing1,3,REN Gang1,3 & LI Xing2,3 1 Department of Computer Science,Tsinghua University,Beijing 100084,China 2 Department of Electronic Engineering,Tsinghua University,Beijing 100084,China 3 Tsinghua National Laboratory for Information Science and Technology(TNList) ,Beijing 100084,China | 2008 | Science in China(Series F)2008，51，11： | 8 |
| 12 | Numerical and experimental investigation of the fracture behavior of shock loaded alumina显示文摘Plate impact expeiments are conducted to investigate the dynamic behavior of alumina by using one stage light gas gun. A ve-locity interferometer system for reflectors (VISAR) is used to obtain Hugoniot elastic limit and the free surface velocity profile,which consists of an elastic wave followed immediately by a dispersive inelastic wave. The stress histories under different impact velocities are measured by in-material manganin gauges. Based on the experimental data a Hugoniot curve is fitted,which shows the compressive characteristics that alumina changes typically from elastic to 'plastic' ,and under higher pressure it will be transferred to similar-fluid state. The turning point of the Hugoniot curve from a high pressure region to a low pressure region is about 11.4 GPa. The fracture process of alumina is simulated by way of finite element code. After the analysis of the fracture mechanism,the numerical results show an important role played by the nucleation and the growth of the cracks in the macro-scopic fracture of the alumina target. The numerical predictions of stress histories are compared with the experimental results,which indicates consistency between them. | REN HuiLan1,SHU XueFeng2 & LI Ping3 1 State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology,Beijing 100081,China 2 Institute of Applied Mechanics and Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China 3 Labroratory for Shock Wave and Detonation Physics Research,Institute of Fluid Physics,CAEP,Mianyang 610059,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，2： | 7 |
| 13 | Analysis of the essential DNA region for OsEBP-89 promoter in response to methyl jasmonic acid显示文摘In rice, the characterization of OsEBP-89 is inducible by various stress- or hormone-stimuli, including ethylene, abscisic acid (ABA), jasmonate acid (JA), drought and cold. Here, we report the investigation of essential DNA region within OsEBP-89 promoter for methyl jasmonic acid (MeJA) induction. PLACE analysis indicates that this promoter sequence contains multiple potential elements in response to various stimuli. First, we fused this promoter with GUS gene and analyzed its expression under MeJA treatment through Agrobacterium infiltration mediating transient expression in tobacco leaves. Our results revealed that this chimeric gene could be inducible by MeJA in tobacco leaves. To further de- termine the crucial sequences responsible for MeJA induction, we generated a series of deletion pro- moters which were fused with GUS reporter gene respectively. The results of transient expression of GUS gene driven by these mutant promoters show that the essential region for MeJA induction is po- sitioned in the region between -1200 and -800 in OsEBP-89 promoter containing a G-box (?1127), which is distinct from the essential region containing ERE (?562) for ACC induction. In all, our finding is helpful in understanding the molecular mechanism of OsEBP-89 expression under different stimuli. | LI Ang1,2, CHEN LiangLiang1,3, REN HaiYun3, WANG XueChen2, ZHANG HaiWen1,4 & HUANG Rong- Feng1,4 1 Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China 2 National Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing 100094, China 3 College of Life Sciences, Beijing Normal University, Beijing 100875, China 4 National Key Facility of Crop Gene Resources and Genetic Improvement, Beijing 100081, China | 2008 | Science China(Life Sciences)2008，51，3： | 6 |
| 14 | “地壳异常压力”学术研讨会显示文摘延用至今的地质作用深度测算方法 ,即重力 /密度法 ,是基于“地下岩石处于静水压力状态” (Heim,1978)和“地下某一深处的垂直压力等于上覆岩石柱的总重量” (ДИННИК,1937)两个理论假设。下面刊登的是“地壳异常压力学术研讨会”专家们的发言 (北京 ,2 0 0 0 . 2 )。到会专家对上述假设和测算方法提出了不同见解 ,指出 ,浅部地壳直至地幔深处的岩石都是固体状态 ,地下的压力是极不均匀的 ,所以对地壳中的地质作用深度的测算必须把所处岩石看作固体 ,并依据固体物理理论 ,也就是说 ,除重力之外 ,构造力、瞬时压力、结晶力、变质作用、岩石相变等都会产生局部巨大的异常压力。因此 ,应该对地壳异常压力进行深入研究以建立更具普适性的深度测算公式。专家们还认为 ,对在全球具有重要地位的大别超高压变质带的形成深度 ,我国科学家认为是 32 km左右 ,属壳内成因 ,并提供了测算数据 ,但该项研究还应深化。 | CHEN Qing-xuan,REN Xi-fei,LU Gu-xian: ( Institute of Geomechanics,CAGS,Beijing 1 0 0 0 81 ,China) ( 2 ) DONG Shen-bao,LIU Rui-xun,CHEN Jing: ( Departmentof Geology,Peking University,Beijing 1 0 0 871 ,China) ( 3 ) WANG Fang-zheng:( Chinese University of Geosciences,Wuhan 4 3 0 0 74 ,China) ( 4) REN Ji-shun,LITing-dong,LIU Dun-yi: ( Institute of Geology,CAGS,Beijing 1 0 0 0 3 7,China) ( 5) ZHAIYu-sheng:( Chinese University of Geosciences,Beijing1 0 0 0 83 ,China) ( 6) ZHANG Bing-xi:( Ministry of Land and Resources,Beijing1 0 0 0 3 5,China) ( 7) SHAO Li-qin:( Ministry of Science and Technology,Beijing 1 0 0 0 3 8,China) | 2000 | 地质力学学报2000，6，3： | 6 |
| 15 | A geometric Model for the Spatial Correlation of an Acoustic Vector Field in Surface-generated Noise显示文摘健全压力和在水平地成层的媒介的表面噪音的粒子速度的空间关联被表明,与一致地在海洋表面上散布的方向性的噪音来源一起。在粒子速度的评估,飞机波浪近似被用于每条事件光线。由于健全来源关联性质和它的择向性的等价,这域的空间关联的解决方案被转变成单身的方向性的来源产生的协调函数的集成。作为一典型水平地成层的媒介,在完美的波导的表面噪音被调查。正常模式和几何模型给的关联系数显示出令人满意的同意。另外,在健全压力之间的规范的协变性和粒子速度的垂直部件与声学的吸收系数成正比,当在半无穷地同类的空间的表面噪音的是零时。 | Yiwang Huang (1) huangyiwang@hrbeu.edu.cn Qunyan Ren (12) Ting Li (3) | 2012 | Journal of Marine Science and Application2012，11，1： | 4 |
| 16 | Theory and methods of global stability analysis for high arch dam显示文摘The global stability of high arch dam is one of the key problems in the safety study of arch dams,but no feasible method with theoretical basis is available.In this paper,based on the stability theory of mechanical system,it is demonstrated that the global failure of high arch dams belongs to a physical instability starting from local strength failure,which is the extreme point instability according to the characteristics of load-displacement curve obtained from the failure process of dam-foundation system. So the global failure of dam-foundation system should be studied with the stability theory of mechanical system.It is also pointed out that the current stability analysis methods used in engineering are consistent with the stability theory,but not established according to the mechanical system stability theory directly.A perfect method can be obtained through the study of physical disturbance equations. | REN QingWen 1,LI Qiang 1,JIANG YaZhou 2 & JIANG XiaoLan 3 1 Department of Engineering Mechanics,Hohai University,Nanjing 210098,China 2 College of Water Conservation and Hydropower Engineering,Hohai University,Nanjing 210098,China 3 Changjiang Academy of Sciences,Wuhan 430010,China | 2011 | Science China(Technological Sciences)2011，54，S1： | 3 |
| 17 | Half-lives and fine structure for the α decay of deformed even-even nuclei显示文摘The α-decay properties of well-deformed even-even nuclei are systematically calculated within the multichannel cluster model (MCCM). Instead of working in the WKB framework, the quasibound solution to the coupled Schro¨dinger equation is presented with outgoing wave boundary conditions, and the coupling potential is taken into full account in terms of the general quantum theories. The calculated α-decay half-lives are found to agree well with the experimental data with a mean factor of less than 2. The fine structure observed in α decay is also well reproduced by the four-channel microscopic calculation. Very strikingly, the MCCM can give relatively precise descriptions of the branching ratio to excited 4+ states, which is often overestimated in the usual WKB calculations. We expect it to be a significant development of theoretical models toward quantitative descriptions of α transitions to high-spin daughter states. | NI DongDong1,2 & REN ZhongZhou1,2,3 1Department of Physics, Nanjing University, Nanjing 210093, China 2Kavli Institute for Theoretical Physics China, Beijing 100190, China 3Center of Theoretical Nuclear Physics, National Laboratory of Heavy-Ion Accelerator, Lanzhou 730000, China | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S1： | 3 |
| 18 | Effect of Thermal Fatigue Loading on Tensile Behavior of H13 Die Steel with Biomimetic Surface显示文摘Biomimetic surface is an effective ways to promote the performance grade and applied range of materials without alteringtheir substrate.Many improved properties such as resisting fatigue,enduring wear,etc,have been achieved by applyingbiomimetic morphology or structure to some engineering material surfaces.In this paper,aiming to reveal the relationshipbetween thermal cracking behavior and mechanical properties of engineering materials with biomimetic surface,biomimeticspecimens were fabricated using laser technique by imitating the heterogeneous structure on the surface of plant leaves.Theeffect of thermal fatigue cycling on the tensile properties of H13 die steel specimens with different surfaces (several types ofbiomimetic surfaces and a smooth surface) was compared and investigated.As a result,due to the coupling effects of themorphological features on the surface and the microstructure characteristics within unit zone,these specimens with biomimeticsurface exhibit remarkably enhanced Ultimate Tensile Strength (UTS) and 0.2% Yield Strength (YS) compared with referencespecimens while corresponding ductility remains largely unaffected even heightened,whether the thermal fatigue loads or not.The relative mechanisms leading to these improvements have been discussed. | Zhihui Zhang~1,Luquan Ren~1,Hong Zhou~2,Zhiwu Han~1,Xin Tong~3,Yu Zhao~1,Li Chen~1 1.Key Laboratory of Bionic Engineering (Ministry of Education,China),Jilin University,Changchun 130022,P.R.China 2.Key Laboratory of Automobile Materials (Ministry of Education,China),Jilin University,Changchun 130022,P.R.China 3.The Department of Materials Surface Engineering,Guangzhou Research Institute of Non-Ferrous Metals,Guangzhou 510651,P.R.China | 2010 | Journal of Bionic Engineering2010，7，4： | 3 |
| 19 | Functional analysis of a reproductive organ predominant expressing promoter in cotton plants显示文摘Transgenic Bt insect-resistant cotton plants have high insect resistance in the early stage of development, but relatively low resistance in the late stage. Substituting a reproductive organ-specific promoter for the CaMV35S promoter presently being used could be an ideal solu-tion. For the first time, the promoter sequence of ADP-ribosylation factor 1 (arf1) gene was iso-lated from Gossypium hirsutumY18 by means of inverse PCR. The sequencing result discovered the unique structure of the arf1 promoter, including four promoter-specific elements, the initiator, TATA box, CAAT box and GC box, and also an intron in 5′-untranslation region. Four plant ex-pression vectors were constructed for functional analysis of the promoter. Based on the pBI121 plant expression vector, four truncated arf1 promoters took the place of the CaMV35S promoter. These vectors were different only in their promoter regions. They were introduced into cotton plants via pollen tube pathway. Histochemical GUS staining and fluorescence quantitative analyses were performed to examine the expression patterns of the GUS gene driven by the 4 arf1 truncated promoters in transgenic cotton plants respectively. The results showed that the arf1 promoter was a typical reproductive organ-specific promoter. Hopefully, the arf1 promoter can be a regulatory element for designing cotton reproductive organs with desired characteris-tics. | REN Maozhi1,3 , CHEN Quanjia2 , LI Li1, ZHANG Rui1 & GUO Sandui1 1. Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China 2. Department of Agronomy, Xinjiang Agricultural University, Urumchi 830052, China 3. College of Life Science and Technology, Shanghai Jiao Tong University, Shanghai 200030, China | 2005 | Science China(Life Sciences)2005，48，5： | 3 |
| 20 | Development of silicon-based microelectrode array显示文摘This paper introduces in details a kind of silicon-based microelectrode array. MEMS (micro-electromechanical system) technology is used in the fabrication of the microelectrode array, which is designed to perform signal recording and electrical stimulation for nerves in neural engineering. A simple fabrication process is developed. An improved model of microelectrodes is brought forward and successfully validated by the excellent match between circuit simulations and electrical measurements, including both magnitude and phase of microelectrode impedance. Compared with the simple one that is usually used, the improved model is believed to be an advance and more accurate. This modeling helps to improve the design of microelectrodes and understand the behavior of interface between electrode and cell. Furthermore, the microelectrode is proved to be a feasible tool for researches in neural engineering by successfully recording neural activities of sciatic nerve of a bullfrog. | LIN JianHui1,2,3, WU XiaoMing1,2,3,4, HUANG PengSheng1,2, FENG Lei5, REN TianLing1,2 & LIU LiTian1,2 1 Institute of Microelectronics, Tsinghua University, Beijing 100084, China 2 Tsinghua National Laboratory for Information Science and Technology, Beijing 100084, China 3 Yangtze Delta Region Institute of Tsinghua University, Jiaxing 314050, China 4 State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai 200050 China 5 Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China | 2009 | Science China(Technological Sciences)2009，52，8： | 3 |
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