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328篇 您的检索式:作者名="Rath A"
    题名 作者 年代 出处 被引量
1Surgical considerations for ‘intrinsic' brainstem gliomas: proposal of a modification in classification显示文摘Mehta VS Chandra PS Singh PK Garg A Rath GK 2009中国神经肿瘤杂志2009,7,3:9
2Calcitriol analog ZK191784 ameliorates acute and chronic dextran sodium sulfate-induced colitis by modulation of intestinal dendritic cell numbers and phenotype显示文摘AIM: To investigate the effects of ZK1916784, a low calcemic analog of calcitriol on intestinal inflammation. METHODS: Acute and chronic colitis was induced by dextran sodium sulfate (DSS) according to standard procedures. Mice were treated intraperitoneally with ZK1916784 or placebo and colonic inflammation was evaluated. Cytokine production by mesenterial lymph node (MLN) cells was measured by ELISA. Immunohistochemistry was performed to detect intestinal dendritic cells (DCs) within the colonic tissue, and the effect of the calcitriol analog on DCs was investigated. RESULTS: Treatment with ZK191784 resulted in significant amelioration of disease with a reduced histological score in acute and chronic intestinal inflammation. In animals with acute DSS colitis, down- regulation of colonic inflammation was associated with a dramatic reduction in the secretion of the proinflammatory cytokine interferon (IFN)-γ and a significant increase in intereleukin (IL)-10 by MLN cells. Similarly, in chronic colitis, IL-10 expression in colonic tissue increased 1.4-fold when mice were treated with ZK191784, whereas expression of the Th1-specific transcription factor T-beta decreased by 81.6%. Lower numbers of infiltrating activated CD11c+ DCs were found in the colon in ZK191784-treated mice with acute DSScolitis, and secretion of proinflammatory cytokines by primary mucosal DCs was inhibited in the presence of the calcitriol analog. CONCLUSION: The calcitriol analog ZK191784 demonstrated significant anti-inflammatory properties in experimental colitis that were at least partially mediated by the immunosuppressive effects of the derivate on mucosal DCs.Ulrike G Strauch Florian Obermeier Nicole Grunwald Nadja Dunger Heiko C Rath Jürgen Schlmerich A Steinmeyer U Zügel HH Herfarth 2007World Journal of Gastroenterology2007,13,48:4
3MicroRNA expression in the adult mouse central nervous system 显示文摘Bak M Silahtaroglu A Moiler M Christensen M Rath MF Skry- abin B 2008RNA2008,14,3:1
4Structure and function of the eukaryotic ribosome:the next frontier 显示文摘Doudna J A Rath V L 2002Cell2002,109,2:1
5A role for the Hsp90 molecular chaperone family in antigen presentation to T lymphocytes via major histocompatibility complex class II molecules显示文摘Rajagopal D Bal V Mayor S George A Rath S 2006Eur J Immunol2006,36,4:1
6Management of' canalicular lacerations : epidmniological aspects and experience with mini-monoka monocanalicular stent 显示文摘Naik MN Kelapure A Rath S 2008Am J Ophthalmol2008,145,2:1
7Effect of rice-straw and phosphorus application on production and emission of methane from tropical rice soil显示文摘RATH A K RAMAKRISHNAN B RAO V R 2005Journal of Plant Nutrition and Soil Science2005,168,2:1
8Arsenic removal from water employing heterogeneous photocatalysis with TiO2 immobilized in PET bottles显示文摘Fostier A H Pereira M S S Rath S 2008Chemosphere2008,72,2:1
9Sorption of norfloxacin in soils: analytical method, kinetics and freundlieh isotherms显示文摘PERUCHI L M FOSTIER A H RATH S 2015Chemosphere2015,119,:1
10Organ chlorines and eggshell thinning in northern Gannets from eastern Canada显示文摘Satpathy S N Rath A K Miishra S R 1997Chemosphere1997,34,:1
111 Matrixmetallop roteinases in inflamm a- tory bowel disease-from basic research to clinical significance显示文摘Rath T Roderfeld M Graf J et a 2009Zgas- troen tero2009,47,8:1
12Morphological detection and quan- tification of lipoprotein (α) deposition in atheromatous lesions of human aorta and coronary arteries 显示文摘Niendorf A Rath M Wolf K 1990Virchows Arch1990,417,2:1
13Electron microscopic tomography of rat-liver mitochondria and their interaction with the endoplasmic reticulum显示文摘 Buttle K Rath B K 1998Biofactors1998,8,34:1
14Management of canalicular lacerations:epidemiological aspects and experience with Mini-Monoka monocanalicular stent显示文摘Naik MN Kelapure A Rath S 0,,:1
15Detection and quantification of lipoprotein in the arterial wall of 107 coronary bypass patients显示文摘Rath M Niendorf A Reblin T 1989Arteriosclerosis1989,9,:1
16Hydrogenated amorphous and polycrystalline silicon TFTs by hotwire CVD显示文摘RATH J K BARBON A SCHROPP R E I 1998J Non-Cryst Solids1998,,:1
17Salvage surgery for reeurrent carcinoma of the hypopharynx and reeonstruetion using jejunal free tissue transfer and peetoralis major muscle pedieled flap显示文摘Dubsky P C Stilt A Rath T Kornfehl J 2007Arch Otolaryngol Head Neck Surg2007,133,:1
18A selective molecularly imprinted polymer-solid phase extraction for the determination of fenitrothion in tomatoes显示文摘de BARROS L A MARTINS I RATH S 2010Anal Bioanal Chem2010,397,3:1
19Production of piglets preselected for sex following in vitro fertilization with X and Y chromosome-bearing spermatozoa sorted by flow cy-tometry显示文摘Rath D Johnson L A Dobrinsky J R 1997Theriogenology1997,47,:1
20Fabrication of thin film silicon solar cells on plastic substrate by very high frequency PECVD显示文摘RATH J K BRINZA M LIU Y BORREMAN A 2010Solar Energy Materials and Solar Cells2010,94,9:1
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