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| 1 | Murine lung eosinophil activation and chemokine production in allergic airway inflammation显示文摘Eosinophils play important roles in asthma and lung infections.Murine models are widely used for assessing the functional significance and mechanistic basis for eosinophil involvements in these diseases.However,little is known about tissue eosinophils in homeostasis.In addition,little data on eosinophil chemokine production during allergic airway inflammation are available.In this study,the properties and functions of homeostatic and activated eosinophils were compared.Eosinophils from normal tissues expressed costimulation and adhesion molecules B7-1,B7-2 and ICAM-1 for Ag presentation but little major histocompatibility complex(MHC)class II,and were found to be poor stimulators of T-cell proliferation.However,these eosinophils expressed high levels of chemokine mRNA including C10,macrophage inflammatory protein(MIP)-1a,MIP-1c,MIP-2,eotaxin and monocyte chemoattractant protein-5(MCP-5),and produced chemokine proteins.Eosinophil intracellular chemokines decreased rapidly with concomitant surface marker downregulation upon in vitro culturing consistent with piecemeal degranulation.Lung eosinophils from mice with induced allergic airway inflammation exhibited increased chemokines mRNA expression and chemokines protein production and upregulated MHC class II and CD11c expression.They were also found to be the predominant producers of the CCR1 ligands CCL6/C10 and CCL9/MIP-1c in inflamed lungs.Eosinophil production of C10 and MIP-1c correlated with the marked influx of CD11bhigh lung dendritic cells during allergic airway inflammation and the high expression of CCR1 on these dendritic cells(DCs).The study provided baseline information on tissue eosinophils,documented the upregulation of activation markers and chemokine production in activated eosinophils,and indicated that eosinophils were a key chemokine-producing cell type in allergic lung inflammation. | C Edward Rose Jr Joanne A Lannigan Paul Kim James J Lee Shu Man Fu Sun-sang J Sung | 2010 | Cellular & Molecular Immunology2010，7，5： | 6 |
| 2 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 3 | Understanding and managing HELLP syndrome : die integral role of aggressive glucocorticoids for mother and child 显示文摘 | Martin JN Jr Rose CH Briery CM | 2006 | Am J Obstet Gynecol2006，195，4： | 1 |
| 4 | Guided wave resonance tuning for pipe inspection显示文摘 | Barshinger J Rose JL Avioli MJ Jr | 2002 | ASME J of Pressure Vessel Technology2002，124，4： | 1 |
| 5 | The index and the Drazin inverse of block triangular matrices显示文摘 | C D Meyer Jr N J Rose | 1977 | SIAM Journal on Applied Mathematics1977，33，1： | 1 |
| 6 | Human neutrophils use the myeloperoxidase - hydren peroxide - chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis显示文摘 | Rose H Crowley JR Heinecke JW | 2002 | J Bio Chem2002，277，30： | 1 |
| 7 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 8 | Postpartum plasma exchange as adjunctive therapy for severe acute fatty liver of pregnancy显示文摘 | Martin JN Jr Birery CM Rose CH | 2008 | J Clin Apher2008，23，4： | 1 |
| 9 | Histologic comparison of autologous fat processing methods显示文摘 | LUCARELLI M J LEMKE B N | 2006 | Opthal Plast Reconstr Surg2006，22，3： | 1 |
| 10 | Histologic comparison of autologous fat processing methods 显示文摘 | Rose Jr JG Lucarelli MJ Lemke BN | 2006 | Ophthal Plast Reconstr Surg2006，22，3： | 1 |
| 11 | Diverse and potentchemokine production by lung CDllbhigh dendritic cells inhomeostasis and in allergic lung inflammation 显示文摘 | Beaty SR Rose CE Jr Sung SS | 2007 | JImmunol2007，178，3： | 1 |
| 12 | Cyclic hydro- static pressure stimulates enhanced bone development in the foetal chick femur in vitro显示文摘 | Henstock JR Rotherham M Rose JB | 2013 | Bone2013，53，2： | 1 |
| 13 | Oclusal and skeletal effects of an oral appliance in the treatment of obstructive sleep apnea 显示文摘 | Rose EC Staats R Virchow Jr C | 2002 | Chest2002，122，3： | 1 |
| 14 | Simultaneous somatosensory evoked potential and electromyographic recordings during lumbosacral devompression and instrumentation显示文摘 | Rose RD Welch WC | 1998 | Neurosurgery1998，42，6： | 1 |
| 15 | Induced pluripotent stem cells from a spinal muscular atrophy patient显示文摘 | Ebert AD Yu J Rose FF Jr | 2009 | Nature2009，457，7227： | 1 |
| 16 | Randomized,controlled clinical trial of point-0f-care limited ultrasonography assistance of central venous cannulation:the third Sonography Outcomes Assessment Program(SOAP-3)Trial显示文摘 | Mi TJ Jr Rose J Briggs WM | 2005 | Crit Care Med2005，33，： | 1 |
| 17 | Histologic comparison of autologous fat processing methods 显示文摘 | Rose JG Jr Lucarelli MJ Lemke BN | 2006 | Ophthal Plast Reconstr Surg2006，22，3： | 1 |
| 18 | Induced pluripotent stem cells from a spinal muscular atrophy patient 显示文摘 | Ebert AD Yu J Rose FF Jr | 2008 | Nature2008，21，： | 1 |
| 19 | Understanding and managing HELLP syndrome: the integral role of aggressive glucocorticoids for mother and child 显示文摘 | Martin JN Jr Rose CH Briery CM | 2006 | Am J Obstet Gyneco12006，195，： | 1 |
| 20 | Occlusal and skeletal effects of oral appliance in the treatment of obstructive sleep apnea 显示文摘 | Rose EC Staats R Virchow C Jr | 2002 | Chest2002，122，3： | 1 |
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