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| 1 | Stereotactic body radiation therapy for non-small cell lung cancer:A review显示文摘Stereotactic body radiation therapy(SBRT) is the treatment of choice for medically inoperable patients with early stage non-small cell lung cancer(NSCLC). A literature search primarily based on PubMed electronic databases was completed in July 2018. Inclusion and exclusion criteria were determined prior to the search, and only prospective clinical trials were included. Nineteen trials from 2005 to 2018 met the inclusion criteria, reporting the outcomes of 1434 patients with central and peripheral early stage NSCLC. Patient eligibility,prescription dose and delivery, and follow up duration varied widely. Threeyears overall survival ranged from 43% to 95% with loco-regional control of up to 98% at 3 years. Up to 33% of patients failed distantly after SBRT at 3 years. SBRT was generally well tolerated with 10%-30% grade 3-4 toxicities and a few treatment-related deaths. No differences in outcomes were observed between conventionally fractionated radiation therapy and SBRT, central and peripheral lung tumors, or inoperable and operable patients. SBRT remains a reasonable treatment option for medically inoperable and select operable patients with early stage NSCLC. SBRT has shown excellent local and regional control with toxicity rates equivalent to surgery. Decreasing fractionation schedules have been consistently shown to be both safe and effective. Distant failure is common, and chemotherapy may be considered for select patients. However, the survival benefit of additional interventions, such as chemotherapy, for early stage NSCLC treated with SBRT remains unclear. | Kavitha M Prezzano Sung Jun Ma Gregory M Hermann Charlotte I Rivers Jorge A Gomez-Suescun Anurag K Singh | 2019 | World Journal of Clinical Oncology2019，10，1： | 10 |
| 2 | Nuclear entry of the circadian regulation mPER1 is controlled by mammalian casein kinase I epsilon 显示文摘 | Vielhaher E Eide E Rivers A | 2000 | Mol Cell Biol2000，20，13： | 1 |
| 3 | Coro- nary perfusion pressure and the return of pontancous cireula- tion in human cardiopulmonary resuscitation 显示文摘 | PARADIS N A MARTIN G B RIVERS E P | 1990 | JAMA1990，263，： | 1 |
| 4 | Pollen tube growth is coupled to the extracellular calcium ion flux and the intracellular calcium gradient effect of BAPTA-type buffers and hypertonic media显示文摘 | Pierson E S Miller D D Callaham D A Shipley A M Rivers B A Cresti M Hepler P K | | 0，，12： | 1 |
| 5 | Feasibility of intensive mobility training to improve gait, balance, and mobility in persons with chronic neurological conditions: a case series显示文摘 | FRITZ S MERLO-RAINS A RIVERS E | 2011 | J Neural Phys Ther2011，35，3： | 1 |
| 6 | Stereotactic radiotherapy for prostate cancer:A review and future directions显示文摘Prostate cancer affects over 200000 men annually in the United States alone.The role of conventionally fractionated external beam radiation therapy (RT) is well established as a treatment option for eligible prostate cancer patients; however,the use of stereotactic body radiotherapy (SBRT) in this setting is less well defined.Within the past decade,there have been a number of studies investigating the feasibility of SBRT as a potential treatment option for prostate cancer patients.SBRT has been well studied in other disease sites,and the shortened treatment course would allow for greater convenience for patients.There may also be implications for toxicity as well as disease control.In this review we present a number of prospective and retrospective trials of SBRT in the treatment of prostate cancer.We focus on factors such as biochemical progression-free survival,prostate specific antigen (PSA) response,and toxicity in order to compare SBRT to established treatment modalities.We also discuss future steps that the clinical community can take to further explore this new treatment approach.We conclude that initial studies examining the use of SBRT in the treatment of prostate cancer have demonstrated impressive rates of biochemical recurrencefree survival and PSA response,while maintaining a relatively favorable acute toxicity profile,though long-term follow-up is needed. | Yusef A Syed Ami K Patel-Yadav Charlotte Rivers Anurag K Singh | 2017 | World Journal of Clinical Oncology2017，8，5： | 1 |
| 7 | A Method for Obtaining Digital Signatures and Public-key Cryptosystem显示文摘 | Rivers R L Shamir A Adleman L | 1978 | Comm ACM1978，21，2： | 1 |
| 8 | A whole-genome RNAi screen identifies an 8@2 gene cluster that inhibits death receptor-mediated apoptosis 显示文摘 | Dompe N Rivers C S Li L Cordes S Schwickart M Punnoose E A | 2011 | Proc Natl Acad Sci USA2011，108，： | 1 |
| 9 | Evi- dence for extreme partitioning of copper into a magmatic va- por phase显示文摘 | Lowenstern J B Mahood G A Rivers M L Sutton S R | 1991 | Nature1991，252，5011： | 1 |
| 10 | Coronary perfusion pressure and the return of spontaneous circulation in human cardiopulmonary resuscitation显示文摘 | Paradis N A Martin G B Rivers E P | | 0，，： | 1 |
| 11 | Expression, purification and characterization of cytochrome P450 BioI: a novel P450 involved in biotin synthesis in Bacillus subtilis 显示文摘 | Green A J Rivers S L Cheesman M | 2001 | J Biol Inorg Chem2001，6，： | 1 |
| 12 | Spinal metastases disease:Analysis of factors detemining functional prognosis and the choice of treatment 显示文摘 | Barcena A Lobato RD River JJ | 1984 | Neurosurgery1984，15，6： | 1 |
| 13 | The nitric oxide-eGMP pathway may mediate communication between sensory afferents and projection neurons in the antennal lobe of Manduea Sexta 显示文摘 | Nighorn A Gibson N J Rivers D M | 1998 | Journal of Neuroscience1998，18，： | 1 |
| 14 | Emotional in-telligence:implications for personal,social,academic,and workplace success显示文摘 | Brackett M A Rivers S E Salovey P | | 0，，01： | 1 |
| 15 | Antiepileptic drugs in the treatment of neuropathic pain显示文摘 | Eisenberg E River Y Shifrin A | 2007 | Drugs2007，67，9： | 1 |
| 16 | Panitumumab monotherapy in patients with metastatic colorectal cancer and cetuximab infusion reactions : a series of four case reports显示文摘 | LANGERAK A RIVER G MITCHELL E | 2009 | Clin Colorectal Cancer2009，8，1： | 1 |
| 17 | Coronary perfu-sion pressure and the return of spontaneous circulation in hu-man cardiopulmonary resuscitation 显示文摘 | Paradis N A Martin G B Rivers E P | 1990 | AMA1990，263，8： | 1 |
| 18 | Inhibition of selectin mediated cell adhesion and prevention of acute inflammation by nonanticeagulant sulfated saccharides显示文摘 | Xie X River AS Zakrzewicz A | 2000 | J Biol Chem2000，275，34： | 1 |
| 19 | A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension 显示文摘 | Chen J Iannone MA Li MS Taylor JD Rivers P Nelsen A J Slentz-Kesler KA Roses A Weiner MP | 2000 | Genome Res2000，10，4： | 1 |
| 20 | Antiepileptic drugs in the treatment of neuropathic pain显示文摘 | Eisenberg E River Y Shifrin A | 2007 | Drugs2007，67，9： | 1 |
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