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| 1 | An elastin-like recombinamer-based bioactive hydrogel embedded with mesenchymal stromal cells as an injectable scaffold for osteochondral repair显示文摘The aim of this study was to evaluate injectable,in situ cross-linkable elastin-like recombinamers(ELRs)for osteochondral repair.Both the ELR-based hydrogel alone and the ELR-based hydrogel embedded with rabbit mesenchymal stromal cells(rMSCs)were tested for the regeneration of critical subchondral defects in 10 New Zealand rabbits.Thus,cylindrical osteochondral defects were filled with an aqueous solution of ELRs and the animals sacrificed at 4months for histological and gross evaluation of features of biomaterial performance,including integration,cellular infiltration,surrounding matrix quality and the new matrix in the defects.Although both approaches helped cartilage regeneration,the results suggest that the specific composition of the rMSC-containing hydrogel permitted adequate bone regeneration,whereas the ELR-based hydrogel alone led to an excellent regeneration of hyaline cartilage.In conclusion,the ELR cross-linker solution can be easily delivered and forms a stable well-integrated hydrogel that supports infiltration and de novo matrix synthesis. | Filippo Cipriani Blanca Arino Palao Israel Gonzalez de Torre Aurelio Vega Castrillo Hector Jose Aguado Hernandez Matilde Alonso Rodrigo Angel Jose Alvarez Barcia Ana Sanchez Veronica Garcıa Diaz Monica Lopez Pena Jose Carlos Rodriguez-Cabello | 2019 | Regenerative Biomaterials2019，6，6： | 3 |
| 2 | National Forest Inventories capture the multifunctionality of managed forests in Germany显示文摘Background:Forests perform various important ecosystem functions that contribute to ecosystem services.In many parts of the world,forest management has shifted from a focus on timber production to multi-purpose forestry,combining timber production with the supply of other forest ecosystem services.However,it is unclear which forest types provide which ecosystem services and to what extent forests primarily managed for timber already supply multiple ecosystem services.Based on a comprehensive dataset collected across 150 forest plots in three regions differing in management intensity and species composition,we develop models to predict the potential supply of 13 ecosystem services.We use those models to assess the level of multifunctionality of managed forests at the national level using national forest inventory data.Results:Looking at the potential supply of ecosystem services,we found trade-offs(e.g.between both bark beetle control or dung decomposition and both productivity or soil carbon stocks)as well as synergies(e.g.for temperature regulation,carbon storage and culturally interesting plants)across the 53 most dominant forest types in Germany.No single forest type provided all ecosystem services equally.Some ecosystem services showed comparable levels across forest types(e.g.decomposition or richness of saprotrophs),while others varied strongly,depending on forest structural attributes(e.g.phosphorous availability or cover of edible plants)or tree species composition(e.g.potential nitrification activity).Variability in potential supply of ecosystem services was only to a lesser extent driven by environmental conditions.However,the geographic variation in ecosystem function supply across Germany was closely linked with the distribution of main tree species.Conclusions:Our results show that forest multifunctionality is limited to subsets of ecosystem services.The importance of tree species composition highlights that a lack of multifunctionality at the stand level can be compensated by managing forests at the landscape level,when stands of complementary forest types are combined.These results imply that multi-purpose forestry should be based on a variety of forest types requiring coordinated planning across larger spatial scales. | Nadja K.Simons María R.Felipe-Lucia Peter Schall Christian Ammer Jürgen Bauhus Nico Blüthgen Steffen Boch François Buscot Markus Fischer Kezia Goldmann Martin M.Gossner Falk Hänsel Kirsten Jung Peter Manning Thomas Nauss Yvonne Oelmann Rodica Pena Andrea Polle Swen C.Renner Michael Schloter Ingo Schöning Ernst-Detlef Schulze Emily F.Solly Elisabeth Sorkau Barbara Stempfhuber Tesfaye Wubet Jörg Müller Sebastian Seibold Wolfgang W.Weisser | 2021 | Forest Ecosystems2021，8，1： | 2 |
| 3 | Partial oxidation of methanol to produce hydrogen over Cu-Zn-based catalysts 显示文摘 | Alejo L Lago R Pena M A | 1997 | Appl Catal A1997，162，12： | 1 |
| 4 | A three-dimensional finite element analysis of the combined behavior of ligaments and menisci in the healthy human knee joint 显示文摘 | Pena E Calvo B Martinez M A | 2006 | Journal of Biomechanics2006，39，9： | 1 |
| 5 | Increased heritability of certain types of anorectal malformations 显示文摘 | Falcone RA Jr Levitt MA Pena A | 2007 | J Pediatr Surg2007，42，1： | 1 |
| 6 | Comparison of esophageal stenoses produced by endoscopic sclerotherapy versus variceal ligation 显示文摘 | de la Pena J Orive A Cuadrado A | 2006 | Gastroenterol Hepatol2006，29，9： | 1 |
| 7 | Unusually high selectivity to C2+ alcohols on bimetallic CoFe catalysts during CO hydrogenation显示文摘 | De la PENA OSHEA V A MENENDEZ N N TORNERO J D FIERRO J L G | 2003 | Catal Lett2003，88，34： | 1 |
| 8 | The role of a dechlorinated PVC as compatibiliser for PVC/polyethylene blends显示文摘 | A Zarraga M E Munoz J J Pena | 2002 | Polymer Bulletin2002，，3： | 1 |
| 9 | The application of exosomes as a nanoscale cancer vaccine 显示文摘 | Tan A H De La Pena Seifalian A M | 2010 | Int J Nanomedicine2010，5，： | 1 |
| 10 | Simulation of an isolated wind diesel system with battery energy storage显示文摘 | Sebastian R Pena A R | 2011 | Electric Power Systems Research2011，，： | 1 |
| 11 | Posterior sagittal ancrectoplasty 显示文摘 | Vries PA Pena A | 1982 | J Periatr Surg1982，17，5： | 1 |
| 12 | Occurrence Of Fumonisins B1 And B2 In Portuguese Maize And Maize-Based Foods Intended For Human Consumption显示文摘 | Silva L Lino C M Pena A | 2007 | Food Addit Contam2007，24，4： | 1 |
| 13 | Microtensile bond strength of new self-adhesive luting agents and conventional multistep systems显示文摘 | Viotti RG Kasaz A Pena CE | 2009 | Prostbot Dent2009，102，5： | 1 |
| 14 | Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction:a cohort study显示文摘 | Collet JP Hulot JS Pena A | | 0，，9660： | 1 |
| 15 | Can we override clopi- dogrel resistance 显示文摘 | Pena A Collet JP Hulot JS | 2009 | Circulation2009，119，21： | 1 |
| 16 | Subacute combined degeneration of the spinal cord: MR findings显示文摘 | Penas M Blanco A Villarejo A | 2002 | Neurologia2002，17，8： | 1 |
| 17 | Determination of organochlorine pesticide residues in honey from the central zone of Portugal and the Valencian community of Spain 显示文摘 | Blasco C Lino CM Pico Y Pena A Font G Silveira M I N | 2004 | Journal of Chromatography A2004，1049，12： | 1 |
| 18 | Long term prognosis value:of anemia in a non-selected population with heart failure显示文摘 | Dominguez A Pena J Perez M | 2007 | Med Clin2007，128，10： | 1 |
| 19 | The sphincter of oddi显示文摘 | Bosch A Pena LR | 2007 | Dig Dis Sci2007，52，5： | 1 |
| 20 | Physico-chemical characterization of lignins from different sources for use in phenolformaldehyde resin synthesis 显示文摘 | Tejado A Pena C Labidi J | 2007 | Bioresource Techn2007，98，8： | 1 |
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