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103篇 您的检索式:作者名="PATRICK D B"
    题名 作者 年代 出处 被引量
1一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) 2009世界临床医学2009,,9:2
2Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong 2003Journal of the American College of Cardiology2003,,8:2
3A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease显示文摘Siobhan B O’Neill Patrick D Mc Laughlin Lee Crush Owen J O’Connor Sebastian R Mc Williams Orla Craig Anne Marie Mc Garrigle Fiona O’Neill Jackie Bye Max F. Ryan Fergus Shanahan Michael M Maher 2013European Radiology2013,,:2
45-Fluorouracil:mechanisms of action and clinical strategies显示文摘Daniel B Bonglev D Paul Harkin Patrick G Johnston 2003Nature Review Cancer2003,5,:1
5Fuzzysets approach to noise impact assessment 显示文摘ENRICO B CHRISTIANE D PATRICK R 2006International Journal of LCA2006,11,4:1
6Primary Gastric B-Cell Lymphoma: Results of a Prospective Multicenter Study显示文摘Wolfgang Fischbach* Brigitte Dragosics? Maria-Elisabeth Kolve-Goebeler§ Christian Ohmann∥ Axel Greiner? Qin Yang∥ Stephan B?hm? Patrick Verreet∥ Olaf Horstmann# Martin Busch** Eckhart Dühmke** Hans-Konrad Müller-Hermelink? Klaus Wilms§ 2000Gastroenterology2000,,5:1
7Evaluating a Chlorophyll Content Meter on Three Coastal Wetland Plant Species 显示文摘Patrick D B 2007Agrieultral Food and Environmental Sciences2007,1,2:1
8Power budgetingof a multiple- input Buck-Boost converter显示文摘Nicholas D B Patrick L C 2005IEEE Transaction on Pow- er Electronics2005,20,6:1
9Increased serum neop- terin levels in adults with down syndrome 显示文摘Mehta P D Patrick B A Dalton A J 2005J Neuroimmtmol2005,164,2:1
10The reduction of silica carbon and silicon carbide 显示文摘Patrick D M Lee J G Ivan B C 1979J Am Ceram Soc1979,62,34:1
11Nanoparticles in cancer therapy and diagnosis显示文摘IRENE B CATHERINE D PATRICK C 2002Adv Drug Deliv Rev2002,54,5:1
12A comparative study of dexmedetomidine with midazolam and midazolam alone for sedation during elective awake fiberoptic intubation显示文摘Bergese S D Patrick B S McSweeney T D 2010J Clin Anesth2010,22,1:1
13Permeability ad channel-mediated transport of boric acid across membrane vesicles isolated from squash roots 显示文摘CHRISTOS D MAARTEN J C PATRICK H B 2000Plant Physiol2000,124,:1
14Boneratamides A-C, new sesquiterpenoids isolated from the marine sponge Axinyssa apl ysinoides显示文摘Williams D E Patrick B O Tahir A 2004J Nat Prod2004,67,:1
15Angiotensin Ⅱ modulation insulin-like growth factor-1 expression in the cardiovascular system 显示文摘Patrick D Marjike B Jie Du 1996Thrend Cardiovasc Med1996,6,:1
16Com- parative structural analysis of human DEAf'Box RNA he- licases 显示文摘PATRICK S TOBIAS K SUSANNE V D B 2010PLoS One2010,5,12:1
17Optimal placement of UV-based communications relay nodes 显示文摘OLEG B PATRICK D KAJ H 2010Journal of Global Optimiza- tion2010,48,4:1
18Genetic variation in wild and hatchery stocks of the black pearl oyster, Pinctqda margatitifera, from Japan显示文摘Patrick D Wada K T Francoise B 1993Aquaculture1993,110,:1
19Atmospheric input of trace metals to the western Mediterranean: uncertainties in modeling dry deposition from cascade impactor data显示文摘Francois D Patrick B M Ulith E 1989Tel-lus1989,41,:1
20Design, test, and evaluation of an electrostatically figured membrane mirror 显示文摘Morre Jr J D Patrick B Gierow P A 2004SPIE2004,5166,:1
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